Bucket-List Cruise Adventures

Pick your sailing — we plan the whole adventure

Bucket-list adventures at every port — where to fly in, and what to do the day(s) before and after.

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Where to? tap as many as you like Caribbean Mediterranean Alaska Bahamas Mexico Northern Europe Hawaii Bermuda Europe Asia Australia & South Pacific Panama Canal South America North America Pacific Middle East Africa
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Filtering From San Diego, California ×One-way ×13+ nights × Clear all
Showing 11 of 11 sailings
Holland America · Nieuw AmsterdamOne-way
Bahamas 16 nights Oct 2 – Oct 18, 2026 from San Diego, California to Fort Lauderdale (Port Everglades), Florida
San Diego, California · Puerto Vallarta, Mexico · … · Fort Lauderdale (Port Everglades), Florida10 ports
San Diego, California · Puerto Vallarta, Mexico · Huatulco, Mexico · Puerto Chiapas, Mexico · Puerto Quetzal, Guatemala · Acajutla, El Salvador · Panama Canal, Panama · Cartagena, Colombia · Half Moon Cay (Little San Salvador Island), Bahamas · Fort Lauderdale (Port Everglades), Florida
★ Bucket-list San Diego ZooHidden Beach at Marietas IslandsCopalitilla Magic WaterfallsPrivate Sumidero Canyon Boat Safari & Chiapa de Co… +6 more
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from $1,529
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Holland America · EurodamOne-way
Caribbean 16 nights Oct 8 – Oct 24, 2026 from San Diego, California to Fort Lauderdale (Port Everglades), Florida
San Diego, California · Cabo San Lucas, Mexico · … · Fort Lauderdale (Port Everglades), Florida10 ports
San Diego, California · Cabo San Lucas, Mexico · Acapulco, Mexico · Huatulco, Mexico · Puerto Chiapas, Mexico · Puerto Quetzal, Guatemala · Puntarenas, Costa Rica · Panama Canal, Panama · Port of Oranjestad, Aruba, Caribbean · Fort Lauderdale (Port Everglades), Florida
★ Bucket-list San Diego ZooEl Arco & Lover's BeachLa Quebrada Cliff DiversCopalitilla Magic Waterfalls +6 more
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from $1,699
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Holland America · ZaandamOne-way
Panama Canal 15 nights Dec 19 – Jan 3, 2027 from San Diego, California to Fort Lauderdale (Port Everglades), Florida
San Diego, California · Cabo San Lucas, Mexico · … · Fort Lauderdale (Port Everglades), Florida9 ports
San Diego, California · Cabo San Lucas, Mexico · Puerto Vallarta, Mexico · Huatulco, Mexico · Puerto Quetzal, Guatemala · Puntarenas, Costa Rica · Panama Canal, Panama · Cartagena, Colombia · Fort Lauderdale (Port Everglades), Florida
★ Bucket-list San Diego ZooEl Arco & Lover's BeachHidden Beach at Marietas IslandsCopalitilla Magic Waterfalls +5 more
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from $1,799
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Princess · Island PrincessOne-way
Pacific 16 nights Jan 29 – Feb 14, 2027 from San Diego, California to Fort Lauderdale (Port Everglades), Florida
San Diego, California · Puerto Vallarta, Mexico · … · Fort Lauderdale (Port Everglades), Florida9 ports
San Diego, California · Puerto Vallarta, Mexico · Huatulco, Mexico · Puerto Chiapas, Mexico · Puntarenas, Costa Rica · Fuerte Amador, Panama · Panama Canal, Panama · Port of Oranjestad, Aruba, Caribbean · Fort Lauderdale (Port Everglades), Florida
★ Bucket-list San Diego ZooHidden Beach at Marietas IslandsCopalitilla Magic WaterfallsPrivate Sumidero Canyon Boat Safari & Chiapa de Co… +5 more
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from $1,803
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Holland America · ZuiderdamOne-way
Bahamas 15 nights Jan 30 – Feb 14, 2027 from San Diego, California to Miami, Florida
San Diego, California · Puerto Vallarta, Mexico · … · Miami, Florida11 ports
San Diego, California · Puerto Vallarta, Mexico · Huatulco, Mexico · Puerto Chiapas, Mexico · Puerto Quetzal, Guatemala · Fuerte Amador, Panama · Panama Canal, Panama · Fuerte Amador, Panama · Cartagena, Colombia · Half Moon Cay (Little San Salvador Island), Bahamas · Miami, Florida
★ Bucket-list San Diego ZooHidden Beach at Marietas IslandsCopalitilla Magic WaterfallsPrivate Sumidero Canyon Boat Safari & Chiapa de Co… +6 more
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from $1,699
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Norwegian · Norwegian StarOne-way
Panama Canal 16 nights Feb 13 – Mar 1, 2027 from San Diego, California to Miami, Florida
San Diego, California · Cabo San Lucas, Mexico · … · Miami, Florida10 ports
San Diego, California · Cabo San Lucas, Mexico · Acapulco, Mexico · Puerto Quetzal, Guatemala · Puntarenas, Costa Rica · Panama City, Panama · Panama Canal, Panama · Cartagena, Colombia · Georgetown, Grand Cayman, Cayman Islands · Miami, Florida
★ Bucket-list San Diego ZooEl Arco & Lover's BeachLa Quebrada Cliff DiversPrivate Antigua Colonial City & Jade Factory Full-… +6 more
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from $1,562
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Holland America · KoningsdamOne-way
Mexico 18 nights Mar 20 – Apr 7, 2027 from San Diego, California to Vancouver, British Columbia
San Diego, California · Cabo San Lucas, Mexico · … · Vancouver, British Columbia11 ports
San Diego, California · Cabo San Lucas, Mexico · Pichilingue (La Paz), Mexico · Loreto, Mexico · San Diego, California · Cabo San Lucas, Mexico · Mazatlan, Mexico · Puerto Vallarta, Mexico · San Diego, California · Victoria, British Columbia · Vancouver, British Columbia
★ Bucket-list San Diego ZooEl Arco & Lover's BeachIsla Espíritu SantoCoronado Island +4 more
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from $1,879
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Holland America · EurodamOne-way
Pacific 16 nights Oct 7 – Oct 23, 2027 from San Diego, California to Fort Lauderdale (Port Everglades), Florida
San Diego, California · Cabo San Lucas, Mexico · … · Fort Lauderdale (Port Everglades), Florida10 ports
San Diego, California · Cabo San Lucas, Mexico · Acapulco, Mexico · Huatulco, Mexico · Puerto Chiapas, Mexico · Puerto Quetzal, Guatemala · Puntarenas, Costa Rica · Panama Canal, Panama · Port of Oranjestad, Aruba, Caribbean · Fort Lauderdale (Port Everglades), Florida
★ Bucket-list San Diego ZooEl Arco & Lover's BeachLa Quebrada Cliff DiversCopalitilla Magic Waterfalls +6 more
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from $2,769
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Royal Caribbean · Serenade of the SeasOne-way
Mexico 15 nights Oct 7 – Oct 22, 2027 from San Diego, California to Tampa, Florida
San Diego, California · Puerto Vallarta, Mexico · … · Tampa, Florida8 ports
San Diego, California · Puerto Vallarta, Mexico · Puerto Quetzal, Guatemala · Puntarenas, Costa Rica · Panama Canal, Panama · Cartagena, Colombia · Georgetown, Grand Cayman, Cayman Islands · Tampa, Florida
★ Bucket-list San Diego ZooHidden Beach at Marietas IslandsPrivate Antigua Colonial City & Jade Factory Full-…Monteverde Cloud Forest +4 more
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from $1,587
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Holland America · Nieuw AmsterdamOne-way
Asia 36 nights Oct 12 – Nov 17, 2027 from San Diego, California to Buenos Aires, Argentina
San Diego, California · Cabo San Lucas, Mexico · … · Buenos Aires, Argentina25 ports
San Diego, California · Cabo San Lucas, Mexico · Huatulco, Mexico · Puerto Quetzal, Guatemala · Puntarenas, Costa Rica · Crossing The Equator · Manta (Quito), Ecuador · Salaverry (Trujillo), Peru · Callao (Lima), Peru · General San Martin, Peru · Arica, Chile · Coquimbo (La Serena), Chile · San Antonio, Santiago, Chile · Puerto Montt, Chile · Puerto Chacabuco, Chile · Chilean, Fjords · Pio Xi (Bruggen) Glacier · Strait OF Magellan · Beagle Channel · Cockburn And Beagle Channels · Punta Arenas, Chile · Ushuaia, Argentina · Stanley, Falkland Islands · Montevideo, Uruguay · Buenos Aires, Argentina
★ Bucket-list San Diego ZooEl Arco & Lover's BeachCopalitilla Magic WaterfallsPrivate Antigua Colonial City & Jade Factory Full-… +18 more
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from $4,529
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Holland America · ZaandamOne-way
Mexico 15 nights Dec 18 – Jan 2, 2028 from San Diego, California to Miami, Florida
San Diego, California · Cabo San Lucas, Mexico · … · Miami, Florida9 ports
San Diego, California · Cabo San Lucas, Mexico · Puerto Vallarta, Mexico · Manzanillo, Mexico · Huatulco, Mexico · Puntarenas, Costa Rica · Panama Canal, Panama · Cartagena, Colombia · Miami, Florida
★ Bucket-list San Diego ZooEl Arco & Lover's BeachHidden Beach at Marietas IslandsColonial Colima & Comala +5 more
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from $2,674
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Itineraries from the Cruisebound catalog + our enrichment; schedules cross-checked against official port authorities. Booking via Cruisebound and CruiseDirect — we may earn a commission, at no extra cost to you.

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MSC Cruises Royal Caribbean Carnival Viking River Costa Norwegian AmaWaterways Princess Celebrity Viking Ocean Avalon Disney Holland America Oceania Virgin Voyages Regent Cunard Seabourn Azamara