Holland America Mediterranean cruises from Barcelona

Ranked by what people search for and where the cruise lines send the most ships.

14-night Barcelona to Civitavecchia (Rome)

Holland America · Nieuw Amsterdam

11 ports
One way
2 departures Jun – Jul 2028
From $2,464 pp
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Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Souda Bay Balos Lagoon & Gramvousa Island: Private Full-Day Tour
Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch

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11-night Barcelona to Piraeus (Athens)

Holland America · Rotterdam

9 ports
One way
Sails Oct 27, 2027
From $1,629 pp
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Palma de Mallorca La Seu Cathedral + Rooftop Terraces Climb
Marseille Calanques National Park Boat Cruise from the Old Port
Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close

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7-night Barcelona to Civitavecchia (Rome)

Holland America · Nieuw Amsterdam

7 ports
One way
Sails Apr 20, 2028
From $1,409 pp
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Palma de Mallorca La Seu Cathedral + Rooftop Terraces Climb
La Goulette Private Full-Day Carthage, Sidi Bou Said & Bardo Museum
Valletta St John's Co-Cathedral & the Caravaggio masterpieces

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11-night Mediterranean from Barcelona

Holland America · Oosterdam

9 ports
Round trip
Sails May 25, 2027
From $2,279 pp
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Malaga Granada & the Alhambra: Spain's Most Famous Monument
Tangier Tangier Kasbah, Medina & American Legation Private Tour
Almeria Private Alhambra Palace & Generalife Gardens from Almeria

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9-night Barcelona to Civitavecchia (Rome)

Holland America · Zuiderdam

8 ports
One way
Sails Feb 17, 2028
From $1,014 pp
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Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Tangier Tangier Kasbah, Medina & American Legation Private Tour
Cadiz (Seville) Real Alcázar de Sevilla: Private Expert-Led Palace Access

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20-night Barcelona to Piraeus (Athens)

Holland America · Nieuw Statendam

13 ports
One way
Sails Jan 16, 2028
From $2,269 pp
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Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port
Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close

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14-night Barcelona to Civitavecchia (Rome)

Holland America · Oosterdam

11 ports
One way
Sails Jun 5, 2027
From $2,459 pp
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Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Souda Bay Balos Lagoon & Gramvousa Island: Private Full-Day Tour
Mykonos Delos: a whole UNESCO island that is one open-air ruin

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14-night Barcelona to Civitavecchia (Rome)

Holland America · Oosterdam

11 ports
One way
Sails Jun 26, 2027
From $2,324 pp
Premium

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Souda Bay Balos Lagoon & Gramvousa Island: Private Full-Day Tour
Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch

See the whole trip →

7-night Barcelona to Piraeus (Athens)

Holland America · Oosterdam

6 ports
One way
Sails Aug 28, 2027
From $1,544 pp
Premium

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Souda Bay Balos Lagoon & Gramvousa Island: Private Full-Day Tour
Mykonos Delos: a whole UNESCO island that is one open-air ruin

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21-night Mediterranean from Barcelona

Holland America · Nieuw Amsterdam

15 ports
Round trip
Sails Aug 6, 2028
From $3,399 pp
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Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Souda Bay Balos Lagoon & Gramvousa Island: Private Full-Day Tour
Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch

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11-night Barcelona to Piraeus (Athens)

Holland America · Oosterdam

11 ports
One way
Sails Apr 23, 2027
From $2,809 pp
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Villefranche Private Riviera Half-Day: Eze, Monaco & Monte Carlo
Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Civitavecchia (Rome) Vatican, Sistine Chapel & Colosseum in One Day (skip-the-line, private)

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13-night Barcelona to Fort Lauderdale (Port Everglades)

Holland America · Oosterdam

5 ports
Repositioning
Sails Dec 9, 2027
From $1,119 pp
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Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Malaga Granada & the Alhambra: Spain's Most Famous Monument
Gibraltar Upper Rock Nature Reserve: Private Taxi Grand Tour

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10-night Barcelona to Piraeus (Athens)

Holland America · Nieuw Amsterdam

10 ports
One way
Sails May 4, 2028
From $2,004 pp
Premium

Villefranche Private Riviera Half-Day: Eze, Monaco & Monte Carlo
Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Civitavecchia (Rome) Vatican, Sistine Chapel & Colosseum in One Day (skip-the-line, private)

See the whole trip →