⚓ Cruises

MSC Cruises cruises from Civitavecchia (Rome)

203 itineraries with a bookable sailing ahead, 335 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › MSC Cruises cruises from Civitavecchia (Rome)

Destination

Caribbean1 Mediterranean199 Middle East2 Pacific1

Page 4 of 6

Ranked by what people search for and where the cruise lines send the most ships.

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jun 27, 2027
From $1,011 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

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7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jul 11, 2027
From $1,086 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jul 25, 2027
From $1,086 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Aug 1, 2027
From $1,156 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Aug 8, 2027
From $1,216 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Aug 22, 2027
From $1,166 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Aug 29, 2027
From $1,116 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Sep 5, 2027
From $1,076 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Sep 12, 2027
From $976 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Sep 19, 2027
From $876 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Sep 26, 2027
From $876 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Oct 3, 2027
From $856 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Oct 10, 2027
From $796 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Oct 17, 2027
From $796 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Oct 24, 2027
From $806 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Divina

5 ports
Round trip
2 departures Oct 2026
From $1,143 pp
Contemporary

Mykonos Delos: a whole UNESCO island that is one open-air ruin
Kusadasi (Ephesus) Private Ephesus Grand Tour: Ruins, Terraces & Virgin Mary
Naples Pompeii with a Licensed Archaeologist

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7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Divina

5 ports
Round trip
2 departures Jul – Sep 2027
From $1,306 pp
Contemporary

Mykonos Delos: a whole UNESCO island that is one open-air ruin
Kusadasi (Ephesus) Private Ephesus Grand Tour: Ruins, Terraces & Virgin Mary
Naples Pompeii with a Licensed Archaeologist

See the whole trip →

2-night Civitavecchia (Rome) to Valencia

MSC Cruises · MSC Sinfonia

2 ports
One way
Sails Jan 14, 2027
From $187 pp
Contemporary

Civitavecchia (Rome) Vatican, Sistine Chapel & Colosseum in One Day (skip-the-line, private)
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium

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10-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Sinfonia

8 ports
Round trip
2 departures Apr 2028
From $1,634 pp
Contemporary

Genoa Sail straight to Portofino from the cruise dock (Golfo Paradiso ferry)
Marseille Calanques National Park Boat Cruise from the Old Port
Malaga Granada & the Alhambra: Spain's Most Famous Monument

See the whole trip →

6-night Civitavecchia (Rome) to Genoa

MSC Cruises · MSC Seaview

6 ports
One way
Sails Nov 8, 2026
From $536 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Tarragona Private Roman Tarraco: Amphitheatre, Circus & Forum

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Grandiosa

6 ports
Round trip
Sails Sep 23, 2026
From $875 pp
Contemporary

Palma de Mallorca La Seu Cathedral + Rooftop Terraces Climb
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Cannes Private Boat to Îles de Lérins: Sainte-Marguerite & Saint-Honorat

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Grandiosa

6 ports
Round trip
Sails Sep 30, 2026
From $1,170 pp
Contemporary

Palma de Mallorca La Seu Cathedral + Rooftop Terraces Climb
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Cannes Private Boat to Îles de Lérins: Sainte-Marguerite & Saint-Honorat

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Grandiosa

6 ports
Round trip
Sails Oct 7, 2026
From $1,080 pp
Contemporary

Palma de Mallorca La Seu Cathedral + Rooftop Terraces Climb
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Cannes Private Boat to Îles de Lérins: Sainte-Marguerite & Saint-Honorat

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Grandiosa

6 ports
Round trip
Sails Oct 14, 2026
From $1,008 pp
Contemporary

Palma de Mallorca La Seu Cathedral + Rooftop Terraces Climb
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Cannes Private Boat to Îles de Lérins: Sainte-Marguerite & Saint-Honorat

See the whole trip →

17-night Civitavecchia (Rome) to Port Canaveral

MSC Cruises · MSC Grandiosa

7 ports
Repositioning
Sails Oct 28, 2026
From $1,424 pp
Contemporary

Palma de Mallorca La Seu Cathedral + Rooftop Terraces Climb
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Funchal Pico do Arieiro to Pico Ruivo: Madeira's Rooftop Ridge Walk

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10-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Magnifica

8 ports
Round trip
Sails Dec 15, 2026
From $1,207 pp
Contemporary

Genoa Sail straight to Portofino from the cruise dock (Golfo Paradiso ferry)
Marseille Calanques National Park Boat Cruise from the Old Port
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb

See the whole trip →

10-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Magnifica

8 ports
Round trip
Sails Dec 25, 2027
From $2,402 pp
Contemporary

Genoa Sail straight to Portofino from the cruise dock (Golfo Paradiso ferry)
Marseille Calanques National Park Boat Cruise from the Old Port
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Orchestra

6 ports
Round trip
Sails Sep 29, 2026
From $1,720 pp
Contemporary

Genoa Sail straight to Portofino from the cruise dock (Golfo Paradiso ferry)
Marseille Calanques National Park Boat Cruise from the Old Port
Tarragona Private Roman Tarraco: Amphitheatre, Circus & Forum

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Orchestra

6 ports
Round trip
Sails Oct 6, 2026
From $949 pp
Contemporary

Genoa Sail straight to Portofino from the cruise dock (Golfo Paradiso ferry)
Marseille Calanques National Park Boat Cruise from the Old Port
Tarragona Private Roman Tarraco: Amphitheatre, Circus & Forum

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Orchestra

6 ports
Round trip
Sails Oct 13, 2026
From $836 pp
Contemporary

Genoa Sail straight to Portofino from the cruise dock (Golfo Paradiso ferry)
Marseille Calanques National Park Boat Cruise from the Old Port
Tarragona Private Roman Tarraco: Amphitheatre, Circus & Forum

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Orchestra

6 ports
Round trip
Sails Oct 20, 2026
From $3,603 pp
Contemporary

Genoa Sail straight to Portofino from the cruise dock (Golfo Paradiso ferry)
Marseille Calanques National Park Boat Cruise from the Old Port
Tarragona Private Roman Tarraco: Amphitheatre, Circus & Forum

See the whole trip →

6-night Civitavecchia (Rome) to Lisbon

MSC Cruises · MSC Sinfonia

6 ports
One way
Sails May 27, 2027
From $729 pp
Contemporary

Genoa Sail straight to Portofino from the cruise dock (Golfo Paradiso ferry)
Marseille Calanques National Park Boat Cruise from the Old Port
Malaga Granada & the Alhambra: Spain's Most Famous Monument

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Fantasia

6 ports
Round trip
Sails Apr 19, 2027
From $793 pp
Contemporary

Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Cannes Private Boat to Îles de Lérins: Sainte-Marguerite & Saint-Honorat
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Fantasia

6 ports
Round trip
Sails May 3, 2027
From $836 pp
Contemporary

Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Cannes Private Boat to Îles de Lérins: Sainte-Marguerite & Saint-Honorat
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Fantasia

6 ports
Round trip
Sails May 10, 2027
From $886 pp
Contemporary

Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Cannes Private Boat to Îles de Lérins: Sainte-Marguerite & Saint-Honorat
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Fantasia

6 ports
Round trip
Sails May 17, 2027
From $896 pp
Contemporary

Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Cannes Private Boat to Îles de Lérins: Sainte-Marguerite & Saint-Honorat
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Fantasia

6 ports
Round trip
Sails May 24, 2027
From $946 pp
Contemporary

Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Cannes Private Boat to Îles de Lérins: Sainte-Marguerite & Saint-Honorat
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Fantasia

6 ports
Round trip
Sails May 31, 2027
From $934 pp
Contemporary

Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Cannes Private Boat to Îles de Lérins: Sainte-Marguerite & Saint-Honorat
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Fantasia

6 ports
Round trip
Sails Jun 7, 2027
From $976 pp
Contemporary

Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Cannes Private Boat to Îles de Lérins: Sainte-Marguerite & Saint-Honorat
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

MSC Cruises · MSC Fantasia

6 ports
Round trip
Sails Jun 14, 2027
From $986 pp
Contemporary

Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Cannes Private Boat to Îles de Lérins: Sainte-Marguerite & Saint-Honorat
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb

See the whole trip →

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