⚓ Cruises

MSC Cruises cruises from Los Angeles

2 itineraries with a bookable sailing ahead, 2 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › MSC Cruises cruises from Los Angeles

Destination

Mediterranean1 Pacific1

Most popular first

Ranked by what people search for and where the cruise lines send the most ships.

Cabo San Lucas

30-night Los Angeles to Marseille

MSC Cruises · MSC Magnifica

13 ports
Repositioning
Sails Apr 7, 2027
From $3,889 pp
Contemporary

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Puntarenas Monteverde Cloud Forest: Private Guided Reserve Walk & Hanging Bridges
Balboa Panama Canal Partial Transit: Miraflores & Gatun Locks

See the whole trip →

San Diego

15-night Los Angeles to Miami

MSC Cruises · MSC Poesia

7 ports
Repositioning
Sails Oct 2, 2026
From $1,240 pp
Contemporary

San Diego San Diego Zoo: Wildlife Showcase at the World's Greatest Zoo
Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Puntarenas Monteverde Cloud Forest: Private Guided Reserve Walk & Hanging Bridges

See the whole trip →

Prefer a calendar? →The ports themselves →