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MSC Cruises cruises from Naples

166 itineraries with a bookable sailing ahead, 327 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › MSC Cruises cruises from Naples

Destination

Caribbean1 Mediterranean165

Page 5 of 5

Ranked by what people search for and where the cruise lines send the most ships.

7-night Mediterranean from Naples

MSC Cruises · MSC Divina

5 ports
Round trip
Sails Aug 19, 2027
From $1,500 pp
Contemporary

Civitavecchia (Rome) Vatican, Sistine Chapel & Colosseum in One Day (skip-the-line, private)
Mykonos Delos: a whole UNESCO island that is one open-air ruin
Kusadasi (Ephesus) Private Ephesus Grand Tour: Ruins, Terraces & Virgin Mary

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7-night Mediterranean from Naples

MSC Cruises · MSC Divina

5 ports
Round trip
Sails Sep 2, 2027
From $1,400 pp
Contemporary

Civitavecchia (Rome) Vatican, Sistine Chapel & Colosseum in One Day (skip-the-line, private)
Mykonos Delos: a whole UNESCO island that is one open-air ruin
Kusadasi (Ephesus) Private Ephesus Grand Tour: Ruins, Terraces & Virgin Mary

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21-night Naples to Buenos Aires

MSC Cruises · MSC Splendida

10 ports
Repositioning
Sails Nov 14, 2027
From $2,051 pp
Contemporary

Genoa Sail straight to Portofino from the cruise dock (Golfo Paradiso ferry)
Civitavecchia (Rome) Vatican, Sistine Chapel & Colosseum in One Day (skip-the-line, private)
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb

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17-night Naples to Rio de Janeiro

MSC Cruises · MSC Divina

7 ports
One way
Sails Oct 29, 2026
From $1,584 pp
Contemporary

Civitavecchia (Rome) Vatican, Sistine Chapel & Colosseum in One Day (skip-the-line, private)
Genoa Sail straight to Portofino from the cruise dock (Golfo Paradiso ferry)
Tarragona Private Roman Tarraco: Amphitheatre, Circus & Forum

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21-night Naples to Santos (Sao Paulo)

MSC Cruises · MSC Virtuosa

11 ports
Repositioning
Sails Nov 13, 2027
From $1,851 pp
Contemporary

Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Marseille Calanques National Park Boat Cruise from the Old Port
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb

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25-night Naples to Miami

MSC Cruises · MSC Meraviglia

14 ports
Repositioning
Sails Oct 17, 2026
From $2,564 pp
Contemporary

Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Marseille Calanques National Park Boat Cruise from the Old Port
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb

See the whole trip →

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