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MSC Cruises cruises from Palermo

162 itineraries with a bookable sailing ahead, 262 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › MSC Cruises cruises from Palermo

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Ranked by what people search for and where the cruise lines send the most ships.

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Jun 17, 2027
From $1,197 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Jun 24, 2027
From $1,187 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Jul 1, 2027
From $1,345 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Jul 8, 2027
From $1,272 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Jul 15, 2027
From $1,272 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Jul 22, 2027
From $1,302 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Jul 29, 2027
From $1,372 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Aug 5, 2027
From $1,432 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Aug 12, 2027
From $1,432 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Aug 19, 2027
From $1,485 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Aug 26, 2027
From $1,332 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Sep 2, 2027
From $1,287 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Sep 9, 2027
From $1,348 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Sep 16, 2027
From $1,504 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Sep 23, 2027
From $1,213 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Sep 30, 2027
From $1,081 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Oct 7, 2027
From $1,002 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Oct 14, 2027
From $1,002 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Oct 21, 2027
From $1,002 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Oct 28, 2027
From $1,002 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Nov 11, 2027
From $1,050 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Nov 25, 2027
From $930 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Dec 2, 2027
From $820 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Dec 9, 2027
From $820 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Dec 16, 2027
From $820 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Dec 23, 2027
From $1,280 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Dec 30, 2027
From $1,760 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Seaview

6 ports
Round trip
Sails Jan 6, 2028
From $840 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Euribia

6 ports
Round trip
Sails Oct 28, 2026
From $1,031 pp
Contemporary

La Goulette Private Full-Day Carthage, Sidi Bou Said & Bardo Museum
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Euribia

6 ports
Round trip
Sails Nov 4, 2026
From $916 pp
Contemporary

La Goulette Private Full-Day Carthage, Sidi Bou Said & Bardo Museum
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Euribia

6 ports
Round trip
Sails Nov 11, 2026
From $1,225 pp
Contemporary

La Goulette Private Full-Day Carthage, Sidi Bou Said & Bardo Museum
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Euribia

6 ports
Round trip
Sails Nov 25, 2026
From $1,100 pp
Contemporary

La Goulette Private Full-Day Carthage, Sidi Bou Said & Bardo Museum
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Euribia

6 ports
Round trip
Sails Dec 16, 2026
From $921 pp
Contemporary

La Goulette Private Full-Day Carthage, Sidi Bou Said & Bardo Museum
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Euribia

6 ports
Round trip
Sails Jan 6, 2027
From $715 pp
Contemporary

La Goulette Private Full-Day Carthage, Sidi Bou Said & Bardo Museum
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Euribia

6 ports
Round trip
Sails Jan 20, 2027
From $730 pp
Contemporary

La Goulette Private Full-Day Carthage, Sidi Bou Said & Bardo Museum
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Euribia

6 ports
Round trip
Sails Feb 3, 2027
From $679 pp
Contemporary

La Goulette Private Full-Day Carthage, Sidi Bou Said & Bardo Museum
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Euribia

6 ports
Round trip
Sails Feb 10, 2027
From $686 pp
Contemporary

La Goulette Private Full-Day Carthage, Sidi Bou Said & Bardo Museum
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Euribia

6 ports
Round trip
Sails Mar 3, 2027
From $755 pp
Contemporary

La Goulette Private Full-Day Carthage, Sidi Bou Said & Bardo Museum
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Euribia

6 ports
Round trip
Sails Mar 31, 2027
From $815 pp
Contemporary

La Goulette Private Full-Day Carthage, Sidi Bou Said & Bardo Museum
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

7-night Mediterranean from Palermo

MSC Cruises · MSC Euribia

6 ports
Round trip
Sails Nov 3, 2027
From $1,020 pp
Contemporary

La Goulette Private Full-Day Carthage, Sidi Bou Said & Bardo Museum
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

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