⚓ Cruises

Mediterranean cruises from Palermo

221 itineraries with a bookable sailing ahead, 363 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › Mediterranean cruises from Palermo

Cruise line

MSC Cruises162 Costa59

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Ranked by what people search for and where the cruise lines send the most ships.

Naples

7-night Mediterranean from Palermo

MSC Cruises · MSC Virtuosa

6 ports
Round trip
Sails Sep 24, 2027
From $1,132 pp
Contemporary

Naples Pompeii with a Licensed Archaeologist
Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Naples

7-night Mediterranean from Palermo

MSC Cruises · MSC Virtuosa

6 ports
Round trip
Sails Oct 1, 2027
From $1,017 pp
Contemporary

Naples Pompeii with a Licensed Archaeologist
Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Naples

7-night Mediterranean from Palermo

MSC Cruises · MSC Virtuosa

6 ports
Round trip
Sails Oct 8, 2027
From $1,007 pp
Contemporary

Naples Pompeii with a Licensed Archaeologist
Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Naples

7-night Mediterranean from Palermo

MSC Cruises · MSC Virtuosa

6 ports
Round trip
Sails Oct 15, 2027
From $952 pp
Contemporary

Naples Pompeii with a Licensed Archaeologist
Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Naples

7-night Mediterranean from Palermo

MSC Cruises · MSC Virtuosa

6 ports
Round trip
Sails Oct 22, 2027
From $937 pp
Contemporary

Naples Pompeii with a Licensed Archaeologist
Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Naples

7-night Mediterranean from Palermo

MSC Cruises · MSC Virtuosa

6 ports
Round trip
Sails Oct 29, 2027
From $937 pp
Contemporary

Naples Pompeii with a Licensed Archaeologist
Livorno (Florence/Pisa) Climb the Leaning Tower of Pisa — the Field of Miracles up close
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Apr 19, 2027
From $812 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Apr 26, 2027
From $905 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails May 3, 2027
From $1,089 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails May 10, 2027
From $811 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails May 17, 2027
From $811 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails May 31, 2027
From $899 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jun 7, 2027
From $981 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jun 14, 2027
From $936 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jun 21, 2027
From $967 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jun 28, 2027
From $1,011 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jul 5, 2027
From $1,072 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jul 12, 2027
From $1,136 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jul 19, 2027
From $1,079 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jul 26, 2027
From $1,132 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Aug 2, 2027
From $1,156 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Aug 9, 2027
From $1,306 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Aug 16, 2027
From $1,364 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Aug 23, 2027
From $1,212 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Aug 30, 2027
From $1,116 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Sep 6, 2027
From $1,133 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Sep 13, 2027
From $987 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Sep 20, 2027
From $922 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Oct 4, 2027
From $806 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Oct 11, 2027
From $796 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

7-night Mediterranean from Palermo

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Oct 18, 2027
From $796 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Valletta

7-night Mediterranean from Palermo

MSC Cruises · MSC Splendida

6 ports
Round trip
Sails Sep 24, 2026
From $1,754 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Valletta

7-night Mediterranean from Palermo

MSC Cruises · MSC Splendida

6 ports
Round trip
Sails Oct 1, 2026
From $1,146 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Valletta

7-night Mediterranean from Palermo

MSC Cruises · MSC Splendida

6 ports
Round trip
Sails Oct 8, 2026
From $1,150 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Valletta

7-night Mediterranean from Palermo

MSC Cruises · MSC Splendida

6 ports
Round trip
Sails Oct 15, 2026
From $1,295 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Valletta

7-night Mediterranean from Palermo

MSC Cruises · MSC Splendida

6 ports
Round trip
Sails Oct 22, 2026
From $1,535 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Valletta

7-night Mediterranean from Palermo

MSC Cruises · MSC Splendida

6 ports
Round trip
Sails Oct 29, 2026
From $1,390 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Valletta

7-night Mediterranean from Palermo

MSC Cruises · MSC Splendida

6 ports
Round trip
Sails Nov 5, 2026
From $631 pp
Contemporary

Valletta St John's Co-Cathedral & the Caravaggio masterpieces
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

5-night Palermo to Genoa

MSC Cruises · MSC Musica

5 ports
One way
Sails Nov 1, 2027
From $479 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Valencia Oceanografic: Walk Beneath the Sharks at Europe's Largest Aquarium
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

Ibiza

5-night Palermo to Genoa

MSC Cruises · MSC Seaview

5 ports
One way
Sails Nov 9, 2026
From $699 pp
Contemporary

Ibiza Formentera Day Trip & Ses Illetes, the 'Spanish Caribbean'
Tarragona Private Roman Tarraco: Amphitheatre, Circus & Forum
Marseille Calanques National Park Boat Cruise from the Old Port

See the whole trip →

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