⚓ Cruises

Mexico cruises from San Diego

81 itineraries with a bookable sailing ahead, 205 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › Mexico cruises from San Diego

Cruise line

Royal Caribbean17 Norwegian6 Disney26 Holland America32

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Ranked by what people search for and where the cruise lines send the most ships.

7-night Mexico from San Diego

Disney · Disney Magic

4 ports
Round trip
Sails Oct 3, 2027
From $1,518 pp
Premium

Ensenada Valle de Guadalupe wine country: boutique winery tastings (Decantos, Monte Xanic, Vena Cava) with a private driver
Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel

See the whole trip →

7-night Mexico from San Diego

Disney · Disney Wonder

4 ports
Round trip
Sails Nov 22, 2026
From $1,808 pp
Premium

Mazatlan Isla de Venados: Snorkeling, Kayaking & Wild Dolphins
Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Ensenada Valle de Guadalupe wine country: boutique winery tastings (Decantos, Monte Xanic, Vena Cava) with a private driver

See the whole trip →

7-night Mexico from San Diego

Disney · Disney Wonder

4 ports
Round trip
Sails Sep 24, 2027
From $1,551 pp
Premium

Ensenada Valle de Guadalupe wine country: boutique winery tastings (Decantos, Monte Xanic, Vena Cava) with a private driver
Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Mazatlan Isla de Venados: Snorkeling, Kayaking & Wild Dolphins

See the whole trip →

6-night Mexico from San Diego

Norwegian · Norwegian Star

3 ports
Round trip
Sails Dec 20, 2026
From $509 pp
Contemporary

San Diego San Diego Zoo: Wildlife Showcase at the World's Greatest Zoo
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel
Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End

See the whole trip →

4-night Mexico from San Diego

Disney · Disney Wonder

3 ports
Round trip
Sails Dec 7, 2026
From $1,025 pp
Premium

San Diego San Diego Zoo: Wildlife Showcase at the World's Greatest Zoo
Avalon Private Golf Cart Tour of Avalon with Expert Local Guide
Ensenada Valle de Guadalupe wine country: boutique winery tastings (Decantos, Monte Xanic, Vena Cava) with a private driver

See the whole trip →

7-night Mexico from San Diego

Norwegian · Norwegian Star

4 ports
Round trip
Sails Dec 26, 2026
From $799 pp
Contemporary

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Mazatlan Isla de Venados: Snorkeling, Kayaking & Wild Dolphins
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel

See the whole trip →

7-night Mexico from San Diego

Norwegian · Norwegian Star

4 ports
Round trip
Sails Feb 6, 2027
From $609 pp
Contemporary

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Mazatlan Isla de Venados: Snorkeling, Kayaking & Wild Dolphins
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel

See the whole trip →

7-night Mexico from San Diego

Disney · Disney Wonder

4 ports
Round trip
Sails Dec 19, 2027
From $2,732 pp
Premium

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel
Mazatlan Isla de Venados: Snorkeling, Kayaking & Wild Dolphins

See the whole trip →

7-night Mexico from San Diego

Disney · Disney Wonder

3 ports
Round trip
Sails Dec 26, 2027
From $2,874 pp
Premium

San Diego San Diego Zoo: Wildlife Showcase at the World's Greatest Zoo
Mazatlan Isla de Venados: Snorkeling, Kayaking & Wild Dolphins
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel

See the whole trip →

12-night Mexico from San Diego

Holland America · Koningsdam

5 ports
Round trip
Sails Dec 18, 2027
From $1,964 pp
Premium

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Ensenada Valle de Guadalupe wine country: boutique winery tastings (Decantos, Monte Xanic, Vena Cava) with a private driver
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel

See the whole trip →

15-night San Diego to Miami

Holland America · Zaandam

9 ports
One way
Sails Dec 18, 2027
From $2,674 pp
Premium

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel
Huatulco Copalitilla Magic Waterfalls: Private Expert-Led Jungle Trek

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7-night Mexico from San Diego

Holland America · Koningsdam

4 ports
Round trip
Sails Nov 14, 2026
From $749 pp
Premium

Avalon Private Golf Cart Tour of Avalon with Expert Local Guide
San Francisco Alcatraz Island: Early-Access Cellhouse Audio Tour
Ensenada Valle de Guadalupe wine country: boutique winery tastings (Decantos, Monte Xanic, Vena Cava) with a private driver

See the whole trip →

7-night Mexico from San Diego

Holland America · Zaandam

4 ports
Round trip
Sails Mar 28, 2027
From $799 pp
Premium

Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel
Mazatlan Isla de Venados: Snorkeling, Kayaking & Wild Dolphins
Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End

See the whole trip →

7-night Mexico from San Diego

Holland America · Zaandam

4 ports
Round trip
Sails Oct 7, 2027
From $1,114 pp
Premium

Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel
Mazatlan Isla de Venados: Snorkeling, Kayaking & Wild Dolphins
Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End

See the whole trip →

7-night Mexico from San Diego

Holland America · Koningsdam

4 ports
Round trip
Sails Nov 20, 2027
From $1,009 pp
Premium

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Mazatlan Isla de Venados: Snorkeling, Kayaking & Wild Dolphins
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel

See the whole trip →

14-night Mexico from San Diego

Holland America · Koningsdam

7 ports
Round trip
Sails Nov 13, 2027
From $1,964 pp
Premium

Ensenada Valle de Guadalupe wine country: boutique winery tastings (Decantos, Monte Xanic, Vena Cava) with a private driver
San Francisco Alcatraz Island: Early-Access Cellhouse Audio Tour
Santa Barbara Santa Ynez Valley: All-Inclusive Private Wine Country Tour

See the whole trip →