⚓ Cruises

South America cruises

260 itineraries with a bookable sailing ahead, 555 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › South America cruises

Sailing from

Buenos Aires63 Santos (Sao Paulo)62 Rio de Janeiro43 Itajai22 Montevideo16 Camboriú12 Paranagua10 Bahia de Salvador9 Valparaiso (Santiago)7 Maceio4 San Antonio3 Buenos Aires2 Lima2 Callao (Lima)2

Cruise line

MSC Cruises153 Princess4 Celebrity9 Viking Ocean12 Oceania5 Holland America3 Silversea3 Regent3 Azamara2 Cunard1 Costa63 Avalon2

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Ranked by what people search for and where the cruise lines send the most ships.

7-night South America from Bahia de Salvador

MSC Cruises · MSC Virtuosa

5 ports
Round trip
Sails Dec 29, 2026
From $2,046 pp
Contemporary

Copacabana Beach Christ the Redeemer: Private Summit Access at Dawn
Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Santos (Sao Paulo) Private Santos Full-Day: Coffee Museum, Monte Serrat & Coast

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7-night South America from Santos (Sao Paulo)

MSC Cruises · MSC Virtuosa

5 ports
Round trip
Sails Dec 26, 2027
From $1,549 pp
Contemporary

Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves
Bahia de Salvador Pelourinho Private Walking Tour with Ivan Bahia Guide
Copacabana Beach Christ the Redeemer: Private Summit Access at Dawn

See the whole trip →

7-night South America from Bahia de Salvador

MSC Cruises · MSC Virtuosa

5 ports
Round trip
Sails Dec 29, 2027
From $1,584 pp
Contemporary

Copacabana Beach Christ the Redeemer: Private Summit Access at Dawn
Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Santos (Sao Paulo) Private Santos Full-Day: Coffee Museum, Monte Serrat & Coast

See the whole trip →

2-night Paranagua to Santos (Sao Paulo)

MSC Cruises · MSC Musica

3 ports
One way
Sails Mar 13, 2027
From $259 pp
Contemporary

Paranagua Serra Verde Express: Private Gold-Class Train to Curitiba
Santos (Sao Paulo) Private Santos Full-Day: Coffee Museum, Monte Serrat & Coast

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6-night South America from Paranagua

MSC Cruises · MSC Musica

5 ports
Round trip
Sails Jan 2, 2028
From $809 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves

See the whole trip →

6-night South America from Itajai

MSC Cruises · MSC Musica

5 ports
Round trip
Sails Jan 3, 2028
From $809 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves

See the whole trip →

9-night South America from Buenos Aires

MSC Cruises · MSC Splendida

6 ports
Round trip
Sails Dec 27, 2026
From $2,623 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Copacabana Beach Christ the Redeemer: Private Summit Access at Dawn

See the whole trip →

8-night South America from Rio de Janeiro

MSC Cruises · MSC Splendida

5 ports
Round trip
Sails Dec 31, 2026
From $2,459 pp
Contemporary

Copacabana Beach Christ the Redeemer: Private Summit Access at Dawn
Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail
Punta del Este Punta del Este Private Sightseeing Tour with Port Pickup

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7-night South America from Rio de Janeiro

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Dec 22, 2026
From $976 pp
Contemporary

Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves
Paranagua Serra Verde Express: Private Gold-Class Train to Curitiba

See the whole trip →

7-night South America from Itajai

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Dec 27, 2026
From $1,653 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail

See the whole trip →

7-night South America from Itajai

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jan 3, 2027
From $1,169 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves

See the whole trip →

7-night South America from Itajai

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jan 10, 2027
From $1,229 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves

See the whole trip →

7-night South America from Paranagua

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jan 16, 2027
From $1,029 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves

See the whole trip →

7-night South America from Itajai

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jan 17, 2027
From $1,016 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves

See the whole trip →

7-night South America from Rio de Janeiro

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jan 19, 2027
From $946 pp
Contemporary

Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves
Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail
Paranagua Serra Verde Express: Private Gold-Class Train to Curitiba

See the whole trip →

7-night South America from Paranagua

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jan 23, 2027
From $896 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail

See the whole trip →

7-night South America from Itajai

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jan 24, 2027
From $896 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail

See the whole trip →

7-night South America from Rio de Janeiro

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jan 26, 2027
From $896 pp
Contemporary

Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves
Paranagua Serra Verde Express: Private Gold-Class Train to Curitiba

See the whole trip →

7-night South America from Itajai

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Jan 31, 2027
From $1,266 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves

See the whole trip →

7-night South America from Rio de Janeiro

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Feb 2, 2027
From $896 pp
Contemporary

Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves
Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail
Paranagua Serra Verde Express: Private Gold-Class Train to Curitiba

See the whole trip →

7-night South America from Paranagua

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Feb 6, 2027
From $996 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves

See the whole trip →

7-night South America from Itajai

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Feb 7, 2027
From $996 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves

See the whole trip →

7-night South America from Rio de Janeiro

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Feb 9, 2027
From $1,046 pp
Contemporary

Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves
Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail
Paranagua Serra Verde Express: Private Gold-Class Train to Curitiba

See the whole trip →

7-night South America from Paranagua

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Feb 13, 2027
From $816 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves

See the whole trip →

7-night South America from Itajai

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Feb 14, 2027
From $816 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves

See the whole trip →

7-night South America from Rio de Janeiro

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Feb 16, 2027
From $829 pp
Contemporary

Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves
Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail
Paranagua Serra Verde Express: Private Gold-Class Train to Curitiba

See the whole trip →

7-night South America from Paranagua

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Feb 20, 2027
From $749 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves

See the whole trip →

7-night South America from Itajai

MSC Cruises · MSC Musica

6 ports
Round trip
Sails Feb 28, 2027
From $919 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves

See the whole trip →

7-night South America from Paranagua

MSC Cruises · MSC Musica

7 ports
Round trip
Sails Dec 26, 2026
From $4,566 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail

See the whole trip →

7-night South America from Rio de Janeiro

MSC Cruises · MSC Musica

7 ports
Round trip
Sails Dec 29, 2026
From $1,397 pp
Contemporary

Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves
Copacabana Beach Christ the Redeemer: Private Summit Access at Dawn

See the whole trip →

7-night South America from Paranagua

MSC Cruises · MSC Musica

7 ports
Round trip
Sails Dec 26, 2027
From $1,641 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail

See the whole trip →

7-night South America from Itajai

MSC Cruises · MSC Musica

7 ports
Round trip
Sails Dec 27, 2027
From $1,641 pp
Contemporary

Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches
Rio de Janeiro Private Full-Day Rio Highlights: Christ, Sugarloaf & Selarón
Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail

See the whole trip →

7-night South America from Rio de Janeiro

MSC Cruises · MSC Musica

7 ports
Round trip
Sails Dec 29, 2027
From $1,641 pp
Contemporary

Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail
Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves
Copacabana Beach Christ the Redeemer: Private Summit Access at Dawn

See the whole trip →

15-night Buenos Aires to San Antonio

Princess · Majestic Princess

9 ports
One way
Sails Dec 7, 2026
From $2,372 pp
Premium

Montevideo Mercado del Puerto: Private Asado Feast & Grill Master Tour
Puerto Madryn Private Full-Day Península Valdés: Orcas, Elephants & Sea Lions
Stanley Private Stanley Highlights & Gentoo Penguin Colony Tour

See the whole trip →

15-night San Antonio to Buenos Aires

Princess · Majestic Princess

9 ports
One way
Sails Dec 22, 2026
From $2,452 pp
Premium

Puerto Montt Private Osorno Volcano & Petrohué Falls Shore Excursion
Punta Arenas Full-Day King Penguin Colony & Tierra del Fuego Expedition
Cockburn And Beagle Channels Isla Martillo: Walk Among Penguins at Estancia Harberton

See the whole trip →

15-night Buenos Aires to San Antonio

Princess · Majestic Princess

9 ports
One way
Sails Nov 21, 2027
From $2,544 pp
Premium

Montevideo Mercado del Puerto: Private Asado Feast & Grill Master Tour
Puerto Madryn Private Full-Day Península Valdés: Orcas, Elephants & Sea Lions
Stanley Private Stanley Highlights & Gentoo Penguin Colony Tour

See the whole trip →

15-night San Antonio to Buenos Aires

Princess · Majestic Princess

9 ports
One way
Sails Dec 6, 2027
From $2,224 pp
Premium

Puerto Montt Private Osorno Volcano & Petrohué Falls Shore Excursion
Punta Arenas Full-Day King Penguin Colony & Tierra del Fuego Expedition
Cockburn And Beagle Channels Isla Martillo: Walk Among Penguins at Estancia Harberton

See the whole trip →