Expect a focused art-history experience built around Leonardo's The Last Supper at Santa Maria delle Grazie. Most tours last 2–3 hours and combine skip-the-line entry to the painting with a short walk through nearby Renaissance spots or a stop at the Science and Technology Museum where you can see models built from his notebooks. The painting itself is smaller than you imagine, strictly timed (usually 15 minutes inside the room), and kept in a carefully climate-controlled space. It's impressive but moves quickly; the real value comes from a good guide explaining the restoration history and context.
Best time to go is April–June or September–October when crowds are lighter and Milan weather is pleasant for walking. Avoid July and August if you can. Expect to pay around €80–150 per person depending on whether it's a small-group tour with an art historian or a larger standard group. Private options push toward the higher end.
Pick a morning slot if possible – you're sharper and the light is better. Skip adding the full Leonardo museum unless you're genuinely into engineering; it's large and can dilute the day. Book as far ahead as you can; the Last Supper slots sell out months in advance.
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