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Showing 72 of 2,334 sailings
Celebrity · Celebrity AscentRound-trip
Mediterranean 10 nights Sep 18 – Sep 28, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Messina, Sicily, Italy · … · Civitavecchia (Rome), Italy9 ports
Civitavecchia (Rome), Italy · Messina, Sicily, Italy · Katakolon (Olympia), Greece · Corfu, Greece · Dubrovnik, Croatia · Split, Croatia · Bar, Montenegro · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayTaormina's Ancient Greek Theatre, framed by Mount…Ancient OlympiaPaleokastritsa Blue Caves & coves by speedboat +3 more
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from $2,428
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy8 ports
Genoa, Italy · Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaSu Nuraxi di Barumini +2 more
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from $721
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MSC Cruises · MSC DivinaRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Mykonos, Greece · … · Civitavecchia (Rome), Italy6 ports
Civitavecchia (Rome), Italy · Mykonos, Greece · Kusadasi (Ephesus), Turkey · Marmaris, Turkey · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayDelosEphesus + the Terrace Houses with a licensed archa…Private Gulet Cruise +1 more
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from $1,188
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Naples, Italy · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalacePompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,810
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed Archaeologist +2 more
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from $1,382
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Costa · Costa ToscanaOne-way
Mediterranean 5 nights Sep 19 – Sep 24, 2026 from Marseille, France to Civitavecchia (Rome), Italy
Marseille, France · Barcelona, Spain · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaSu Nuraxi di BaruminiPompeii with a Licensed Archaeologist +1 more
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from $917
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 19 – Sep 26, 2026 from Naples, Italy
Naples, Italy · Livorno (Florence/Pisa), Italy · … · Naples, Italy7 ports
Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada Familia +2 more
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from $3,670
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 19 – Sep 26, 2026 from Marseille, France
Marseille, France · Genoa, Italy · … · Marseille, France7 ports
Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount… +2 more
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from $1,734
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Carnival · Carnival LegendRound-trip
Mediterranean 12 nights Sep 20, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Kusadasi (Ephesus), Turkey · … · Civitavecchia (Rome), Italy9 ports
Civitavecchia (Rome), Italy · Kusadasi (Ephesus), Turkey · Kavala, Greece · Istanbul, Turkey · Mykonos, Greece · Piraeus (Athens), Greece · Katakolon (Olympia), Greece · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayEphesus + the Terrace Houses with a licensed archa…Ancient PhilippiHagia Sophia + the upper gallery mosaics with a li… +4 more
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from $1,139
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Barcelona, Spain
Barcelona, Spain · Balearic sea darkest spot · … · Barcelona, Spain8 ports
Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Barcelona, Spain
★ Bucket-list Sagrada FamiliaSu Nuraxi di BaruminiPompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $545
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Marseille, France · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M… +2 more
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from $2,390
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Genoa, Italy
Genoa, Italy · Naples, Italy · … · Genoa, Italy7 ports
Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $4,232
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Royal Caribbean · Legend Of The SeasRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Barcelona, Spain
Barcelona, Spain · Palma de Mallorca, Spain · … · Barcelona, Spain7 ports
Barcelona, Spain · Palma de Mallorca, Spain · Marseille, France · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy · Naples, Italy · Barcelona, Spain
★ Bucket-list Sagrada FamiliaLa Seu Cathedral + Rooftop Terraces ClimbCalanques National Park Boat Cruise from the Old P…Private Cinque Terre by Minivan & Ferryboat from L… +2 more
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from $3,012
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Royal Caribbean · Odyssey of the SeasRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Santorini (Thira), Greece · … · Civitavecchia (Rome), Italy6 ports
Civitavecchia (Rome), Italy · Santorini (Thira), Greece · Ephesus, Turkey · Mykonos, Greece · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySemi-Private Caldera Catamaran with Hot Springs &…Private Ephesus Tour with Expert Local Guide & On-…Delos +1 more
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from $1,897
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MSC Cruises · MSC DivinaRound-trip
Mediterranean 7 nights Sep 21 – Sep 28, 2026 from Kusadasi (Ephesus), Turkey
Kusadasi (Ephesus), Turkey · Marmaris, Turkey · … · Kusadasi (Ephesus), Turkey6 ports
Kusadasi (Ephesus), Turkey · Marmaris, Turkey · Naples, Italy · Civitavecchia (Rome), Italy · Mykonos, Greece · Kusadasi (Ephesus), Turkey
★ Bucket-list Ephesus + the Terrace Houses with a licensed archa…Private Gulet CruisePompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One Day +1 more
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from $3,184
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 21 – Sep 28, 2026 from Marseille, France
Marseille, France · Barcelona, Spain · … · Marseille, France7 ports
Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M…Cappella Palatina & the Norman Palace +2 more
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from $1,203
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 21 – Sep 28, 2026 from Naples, Italy
Naples, Italy · Messina, Sicily, Italy · … · Naples, Italy7 ports
Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,237
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Celebrity · Celebrity EquinoxOne-way
Mediterranean 9 nights Sep 22 – Oct 1, 2026 from Civitavecchia (Rome), Italy to Barcelona, Spain
Civitavecchia (Rome), Italy · Naples, Italy · … · Barcelona, Spain7 ports
Civitavecchia (Rome), Italy · Naples, Italy · La Spezia (Cinque Terre), Italy · Portofino, Italy · Villefranche, France · Marseille, France · Barcelona, Spain
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistPrivate Cinque Terre by Minivan & Ferryboat from L…Private Yacht Charter +3 more
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from $1,815
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 22 – Sep 29, 2026 from Barcelona, Spain
Barcelona, Spain · La Goulette, Tunisia · … · Barcelona, Spain7 ports
Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain
★ Bucket-list Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M…Cappella Palatina & the Norman PalacePompeii with a Licensed Archaeologist +2 more
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from $2,549
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 22 – Sep 29, 2026 from Messina, Sicily, Italy
Messina, Sicily, Italy · Valletta, Malta · … · Messina, Sicily, Italy7 ports
Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy
★ Bucket-list Taormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,871
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Viking Ocean · Viking SeaOne-way
Mediterranean 10 nights Sep 22 – Oct 2, 2026 from Tarragona, Spain to Piraeus (Athens), Greece
Tarragona, Spain · Marseille, France · … · Piraeus (Athens), Greece10 ports
Tarragona, Spain · Marseille, France · Villefranche, France · Florence, Italy · Civitavecchia (Rome), Italy · Naples, Italy · Messina, Sicily, Italy · Sail the Ionian Sea · Heraklion, Crete, Greece · Piraeus (Athens), Greece
★ Bucket-list Private Roman TarracoCalanques National Park Boat Cruise from the Old P…Private Riviera Half-DayUffizi Gallery +5 more
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from $6,599
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Viking Ocean · Viking VestaOne-way
Mediterranean 7 nights Sep 22 – Sep 29, 2026 from Civitavecchia (Rome), Italy to Fusina (Venice), Italy
Civitavecchia (Rome), Italy · Naples, Italy · … · Fusina (Venice), Italy7 ports
Civitavecchia (Rome), Italy · Naples, Italy · Messina, Sicily, Italy · Crotone · Bari, Italy · Sibenik, Croatia · Fusina (Venice), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…Capo Colonna & Santa Severina +3 more
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from $6,499
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 23 – Sep 30, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dock +2 more
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from $1,886
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Sep 24 – Oct 1, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Genoa, Italy · … · Civitavecchia (Rome), Italy9 ports
Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Balearic sea darkest spot · Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Sagrada Familia +2 more
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from $775
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MSC Cruises · MSC DivinaRound-trip
Mediterranean 7 nights Sep 24 – Oct 1, 2026 from Naples, Italy
Naples, Italy · Civitavecchia (Rome), Italy · … · Naples, Italy6 ports
Naples, Italy · Civitavecchia (Rome), Italy · Mykonos, Greece · Kusadasi (Ephesus), Turkey · Marmaris, Turkey · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One DayDelosEphesus + the Terrace Houses with a licensed archa… +1 more
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from $1,845
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Royal Caribbean · Legend Of The SeasRound-trip
Mediterranean 7 nights Sep 24 – Oct 1, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Naples, Italy · … · Civitavecchia (Rome), Italy7 ports
Civitavecchia (Rome), Italy · Naples, Italy · Barcelona, Spain · Palma de Mallorca, Spain · Marseille, France · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistSagrada FamiliaLa Seu Cathedral + Rooftop Terraces Climb +2 more
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from $2,648
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy8 ports
Genoa, Italy · Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaSu Nuraxi di Barumini +2 more
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from $711
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MSC Cruises · MSC DivinaRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Mykonos, Greece · … · Civitavecchia (Rome), Italy6 ports
Civitavecchia (Rome), Italy · Mykonos, Greece · Kusadasi (Ephesus), Turkey · Marmaris, Turkey · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayDelosEphesus + the Terrace Houses with a licensed archa…Private Gulet Cruise +1 more
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from $1,115
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Naples, Italy · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalacePompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P… +2 more
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from $2,697
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed Archaeologist +2 more
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from $1,112
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Sep 26 – Oct 3, 2026 from Marseille, France
Marseille, France · Barcelona, Spain · … · Marseille, France8 ports
Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaSu Nuraxi di BaruminiPompeii with a Licensed Archaeologist +2 more
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from $992
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 26 – Oct 3, 2026 from Naples, Italy
Naples, Italy · Livorno (Florence/Pisa), Italy · … · Naples, Italy7 ports
Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada Familia +2 more
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from $2,640
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 26 – Oct 3, 2026 from Marseille, France
Marseille, France · Genoa, Italy · … · Marseille, France7 ports
Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount… +2 more
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from $1,079
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Princess · Sun PrincessOne-way
Mediterranean 7 nights Sep 26 – Oct 3, 2026 from Civitavecchia (Rome), Italy to Piraeus (Athens), Greece
Civitavecchia (Rome), Italy · Naples, Italy · … · Piraeus (Athens), Greece6 ports
Civitavecchia (Rome), Italy · Naples, Italy · Chania, Greece · Kusadasi (Ephesus), Turkey · Mykonos, Greece · Piraeus (Athens), Greece
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistSamaria GorgeEphesus + the Terrace Houses with a licensed archa… +2 more
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from $1,489
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Sep 27 – Oct 4, 2026 from Barcelona, Spain
Barcelona, Spain · Balearic sea darkest spot · … · Barcelona, Spain8 ports
Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Barcelona, Spain
★ Bucket-list Sagrada FamiliaSu Nuraxi di BaruminiPompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $685
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 27 – Oct 4, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Marseille, France · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M… +2 more
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from $957
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 27 – Oct 4, 2026 from Genoa, Italy
Genoa, Italy · Naples, Italy · … · Genoa, Italy7 ports
Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,385
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Royal Caribbean · Legend Of The SeasRound-trip
Mediterranean 7 nights Sep 27 – Oct 4, 2026 from Barcelona, Spain
Barcelona, Spain · Palma de Mallorca, Spain · … · Barcelona, Spain7 ports
Barcelona, Spain · Palma de Mallorca, Spain · Marseille, France · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy · Naples, Italy · Barcelona, Spain
★ Bucket-list Sagrada FamiliaLa Seu Cathedral + Rooftop Terraces ClimbCalanques National Park Boat Cruise from the Old P…Private Cinque Terre by Minivan & Ferryboat from L… +2 more
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from $1,948
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Royal Caribbean · Odyssey of the SeasRound-trip
Mediterranean 7 nights Sep 27 – Oct 4, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Santorini (Thira), Greece · … · Civitavecchia (Rome), Italy6 ports
Civitavecchia (Rome), Italy · Santorini (Thira), Greece · Ephesus, Turkey · Mykonos, Greece · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySemi-Private Caldera Catamaran with Hot Springs &…Private Ephesus Tour with Expert Local Guide & On-…Delos +1 more
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from $1,995
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Celebrity · Celebrity AscentRound-trip
Mediterranean 11 nights Sep 28 – Oct 9, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Chania, Greece · … · Civitavecchia (Rome), Italy8 ports
Civitavecchia (Rome), Italy · Chania, Greece · Santorini (Thira), Greece · Ephesus, Turkey · Istanbul, Turkey · Mykonos, Greece · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySamaria GorgeSemi-Private Caldera Catamaran with Hot Springs &…Private Ephesus Tour with Expert Local Guide & On-… +3 more
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from $1,972
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MSC Cruises · MSC DivinaRound-trip
Mediterranean 7 nights Sep 28 – Oct 5, 2026 from Kusadasi (Ephesus), Turkey
Kusadasi (Ephesus), Turkey · Marmaris, Turkey · … · Kusadasi (Ephesus), Turkey6 ports
Kusadasi (Ephesus), Turkey · Marmaris, Turkey · Naples, Italy · Civitavecchia (Rome), Italy · Mykonos, Greece · Kusadasi (Ephesus), Turkey
★ Bucket-list Ephesus + the Terrace Houses with a licensed archa…Private Gulet CruisePompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One Day +1 more
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from $3,400
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 28 – Oct 5, 2026 from Marseille, France
Marseille, France · Barcelona, Spain · … · Marseille, France7 ports
Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M…Cappella Palatina & the Norman Palace +2 more
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from $710
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 28 – Oct 5, 2026 from Naples, Italy
Naples, Italy · Messina, Sicily, Italy · … · Naples, Italy7 ports
Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,027
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Royal Caribbean · Brilliance of the SeasOne-way
Mediterranean 7 nights Sep 28 – Oct 5, 2026 from Civitavecchia (Rome), Italy to Piraeus (Athens), Greece
Civitavecchia (Rome), Italy · Naples, Italy · … · Piraeus (Athens), Greece7 ports
Civitavecchia (Rome), Italy · Naples, Italy · Messina, Sicily, Italy · Santorini (Thira), Greece · Ephesus, Turkey · Mykonos, Greece · Piraeus (Athens), Greece
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…Semi-Private Caldera Catamaran with Hot Springs &… +3 more
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from $1,331
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 29 – Oct 6, 2026 from Barcelona, Spain
Barcelona, Spain · La Goulette, Tunisia · … · Barcelona, Spain7 ports
Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain
★ Bucket-list Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M…Cappella Palatina & the Norman PalacePompeii with a Licensed Archaeologist +2 more
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from $1,092
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 29 – Oct 6, 2026 from Messina, Sicily, Italy
Messina, Sicily, Italy · Valletta, Malta · … · Messina, Sicily, Italy7 ports
Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy
★ Bucket-list Taormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,684
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Regent · Seven Seas MarinerOne-way
Mediterranean 13 nights Sep 29 – Oct 12, 2026 from Civitavecchia (Rome), Italy to Piraeus (Athens), Greece
Civitavecchia (Rome), Italy · Naples, Italy · … · Piraeus (Athens), Greece14 ports
Civitavecchia (Rome), Italy · Naples, Italy · Willis Island · La Goulette, Tunisia · Valletta, Malta · Willis Island · Dubrovnik, Croatia · Bari, Italy · Kotor, Montenegro · Corfu, Greece · Katakolon (Olympia), Greece · Santorini (Thira), Greece · Willis Island · Piraeus (Athens), Greece
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistZodiac Circumnavigation of Willis IslandPrivate Full-Day Carthage, Sidi Bou Said & Bardo M… +8 more
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from $14,349
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Costa · Costa ToscanaOne-way
Mediterranean 3 nights Sep 30 – Oct 3, 2026 from Naples, Italy to Marseille, France
Naples, Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France
★ Bucket-list Pompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…
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from $477
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 30 – Oct 7, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dock +2 more
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from $1,103
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Viking Ocean · Viking SkyOne-way
Mediterranean 7 nights Sep 30 – Oct 7, 2026 from Civitavecchia (Rome), Italy to Chioggia, Venice, Italy
Civitavecchia (Rome), Italy · Naples, Italy · … · Chioggia, Venice, Italy7 ports
Civitavecchia (Rome), Italy · Naples, Italy · Catania, Sicily, Italy · Crotone · Bari, Italy · Sibenik, Croatia · Chioggia, Venice, Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistMount Etna Private Jeep Summit Tour from Catania P…Capo Colonna & Santa Severina +3 more
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from $6,499
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Oct 1 – Oct 8, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Genoa, Italy · … · Civitavecchia (Rome), Italy8 ports
Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Sagrada Familia +2 more
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from $705
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MSC Cruises · MSC DivinaRound-trip
Mediterranean 7 nights Oct 1 – Oct 8, 2026 from Naples, Italy
Naples, Italy · Civitavecchia (Rome), Italy · … · Naples, Italy6 ports
Naples, Italy · Civitavecchia (Rome), Italy · Mykonos, Greece · Kusadasi (Ephesus), Turkey · Marmaris, Turkey · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One DayDelosEphesus + the Terrace Houses with a licensed archa… +1 more
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from $1,110
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Royal Caribbean · Legend Of The SeasRound-trip
Mediterranean 7 nights Oct 1 – Oct 8, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Naples, Italy · … · Civitavecchia (Rome), Italy7 ports
Civitavecchia (Rome), Italy · Naples, Italy · Barcelona, Spain · Palma de Mallorca, Spain · Marseille, France · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistSagrada FamiliaLa Seu Cathedral + Rooftop Terraces Climb +2 more
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from $1,895
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Carnival · Carnival LegendRound-trip
Mediterranean 9 nights Oct 2, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Split, Croatia · … · Civitavecchia (Rome), Italy7 ports
Civitavecchia (Rome), Italy · Split, Croatia · Kotor, Montenegro · Dubrovnik, Croatia · Corfu, Greece · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayDiocletian's PalaceClimb the City Walls to San Giovanni FortressWalk Dubrovnik's Ancient City Walls +2 more
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from $924
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Celebrity · Celebrity XcelRound-trip
Mediterranean 10 nights Oct 2 – Oct 12, 2026 from Barcelona, Spain
Barcelona, Spain · Naples, Italy · … · Barcelona, Spain8 ports
Barcelona, Spain · Naples, Italy · Messina, Sicily, Italy · Civitavecchia (Rome), Italy · Portofino, Italy · La Spezia (Cinque Terre), Italy · Villefranche, France · Barcelona, Spain
★ Bucket-list Sagrada FamiliaPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…Vatican, Sistine Chapel & Colosseum in One Day +3 more
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from $4,833
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Oct 2 – Oct 9, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy8 ports
Genoa, Italy · Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaSu Nuraxi di Barumini +2 more
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from $711
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MSC Cruises · MSC DivinaRound-trip
Mediterranean 7 nights Oct 2 – Oct 9, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Mykonos, Greece · … · Civitavecchia (Rome), Italy6 ports
Civitavecchia (Rome), Italy · Mykonos, Greece · Kusadasi (Ephesus), Turkey · Marmaris, Turkey · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayDelosEphesus + the Terrace Houses with a licensed archa…Private Gulet Cruise +1 more
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from $3,016
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Oct 2 – Oct 9, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Naples, Italy · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalacePompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P… +2 more
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from $929
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 2 – Oct 9, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed Archaeologist +2 more
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from $1,059
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Viking Ocean · Viking SeaOne-way
Mediterranean 14 nights Oct 2 – Oct 16, 2026 from Piraeus (Athens), Greece to Civitavecchia (Rome), Italy
Piraeus (Athens), Greece · Crete, Greece · … · Civitavecchia (Rome), Italy14 ports
Piraeus (Athens), Greece · Crete, Greece · Kalamata, Greece · Corfu, Greece · Dubrovnik, Croatia · Ancona, Italy · Chioggia, Venice, Italy · Zadar, Croatia · Split, Croatia · Bari, Italy · Sail the Mediterranean Sea · Sicily (syracuse) · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list The Acropolis & Parthenon, Guided Skip-the-LineBalos Lagoon & Gramvousa IslandAncient MessenePaleokastritsa Blue Caves & coves by speedboat +9 more
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from $9,099
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Oct 3 – Oct 10, 2026 from Marseille, France
Marseille, France · Barcelona, Spain · … · Marseille, France8 ports
Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaSu Nuraxi di BaruminiPompeii with a Licensed Archaeologist +2 more
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from $992
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Oct 3 – Oct 10, 2026 from Naples, Italy
Naples, Italy · Livorno (Florence/Pisa), Italy · … · Naples, Italy7 ports
Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada Familia +2 more
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from $1,163
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 3 – Oct 10, 2026 from Marseille, France
Marseille, France · Genoa, Italy · … · Marseille, France7 ports
Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount… +2 more
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from $1,080
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Princess · Sun PrincessOne-way
Mediterranean 7 nights Oct 3 – Oct 10, 2026 from Piraeus (Athens), Greece to Barcelona, Spain
Piraeus (Athens), Greece · Bar, Montenegro · … · Barcelona, Spain6 ports
Piraeus (Athens), Greece · Bar, Montenegro · Corfu, Greece · Messina, Sicily, Italy · Naples, Italy · Barcelona, Spain
★ Bucket-list The Acropolis & Parthenon, Guided Skip-the-LinePaleokastritsa Blue Caves & coves by speedboatTaormina's Ancient Greek Theatre, framed by Mount…Pompeii with a Licensed Archaeologist +1 more
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from $2,089
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Viking Ocean · Viking NeptuneOne-way
Mediterranean 7 nights Oct 3 – Oct 10, 2026 from Civitavecchia (Rome), Italy to Fusina (Venice), Italy
Civitavecchia (Rome), Italy · Naples, Italy · … · Fusina (Venice), Italy7 ports
Civitavecchia (Rome), Italy · Naples, Italy · Messina, Sicily, Italy · Crotone · Bari, Italy · Sibenik, Croatia · Fusina (Venice), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…Capo Colonna & Santa Severina +3 more
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from $6,499
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Oct 4 – Oct 11, 2026 from Barcelona, Spain
Barcelona, Spain · Balearic sea darkest spot · … · Barcelona, Spain8 ports
Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Barcelona, Spain
★ Bucket-list Sagrada FamiliaSu Nuraxi di BaruminiPompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $745
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Oct 4 – Oct 11, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Marseille, France · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M… +2 more
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from $879
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 4 – Oct 11, 2026 from Genoa, Italy
Genoa, Italy · Naples, Italy · … · Genoa, Italy7 ports
Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,385
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Royal Caribbean · Legend Of The SeasRound-trip
Mediterranean 7 nights Oct 4 – Oct 11, 2026 from Barcelona, Spain
Barcelona, Spain · Palma de Mallorca, Spain · … · Barcelona, Spain7 ports
Barcelona, Spain · Palma de Mallorca, Spain · Marseille, France · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy · Naples, Italy · Barcelona, Spain
★ Bucket-list Sagrada FamiliaLa Seu Cathedral + Rooftop Terraces ClimbCalanques National Park Boat Cruise from the Old P…Private Cinque Terre by Minivan & Ferryboat from L… +2 more
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from $1,810
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Royal Caribbean · Odyssey of the SeasRound-trip
Mediterranean 7 nights Oct 4 – Oct 11, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Santorini (Thira), Greece · … · Civitavecchia (Rome), Italy6 ports
Civitavecchia (Rome), Italy · Santorini (Thira), Greece · Ephesus, Turkey · Mykonos, Greece · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySemi-Private Caldera Catamaran with Hot Springs &…Private Ephesus Tour with Expert Local Guide & On-…Delos +1 more
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from $2,397
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MSC Cruises · MSC DivinaRound-trip
Mediterranean 7 nights Oct 5 – Oct 12, 2026 from Kusadasi (Ephesus), Turkey
Kusadasi (Ephesus), Turkey · Marmaris, Turkey · … · Kusadasi (Ephesus), Turkey6 ports
Kusadasi (Ephesus), Turkey · Marmaris, Turkey · Naples, Italy · Civitavecchia (Rome), Italy · Mykonos, Greece · Kusadasi (Ephesus), Turkey
★ Bucket-list Ephesus + the Terrace Houses with a licensed archa…Private Gulet CruisePompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One Day +1 more
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from $777
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Oct 5 – Oct 12, 2026 from Marseille, France
Marseille, France · Barcelona, Spain · … · Marseille, France7 ports
Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M…Cappella Palatina & the Norman Palace +2 more
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from $3,680
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