⚓ Cruises

Panama Canal cruises from Cartagena

9 itineraries with a bookable sailing ahead, 14 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › Panama Canal cruises from Cartagena

Most popular first

Ranked by what people search for and where the cruise lines send the most ships.

Willemstad

7-night Panama Canal from Cartagena

Royal Caribbean · Grandeur of the Seas

4 ports
Round trip
3 departures Jan – Apr 2027
From $1,207 pp
Contemporary

Willemstad Private Full-Day Curaçao Island Tour with Local Expert
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

See the whole trip →

Port of Oranjestad

7-night Panama Canal from Cartagena

Royal Caribbean · Grandeur of the Seas

4 ports
Round trip
3 departures Sep 2026 – Mar 2027
From $1,294 pp
Contemporary

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Willemstad Private Full-Day Curaçao Island Tour with Local Expert
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

See the whole trip →

Willemstad

7-night Panama Canal from Cartagena

Royal Caribbean · Grandeur of the Seas

4 ports
Round trip
2 departures Jan – Mar 2028
From $922 pp
Contemporary

Willemstad Private Full-Day Curaçao Island Tour with Local Expert
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

See the whole trip →

Kralendijk

7-night Panama Canal from Cartagena

Royal Caribbean · Grandeur of the Seas

5 ports
Round trip
Sails Jan 24, 2027
From $1,319 pp
Contemporary

Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park
Willemstad Private Full-Day Curaçao Island Tour with Local Expert
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ

See the whole trip →

Willemstad

7-night Panama Canal from Cartagena

Royal Caribbean · Grandeur of the Seas

5 ports
Round trip
Sails Jan 31, 2027
From $1,323 pp
Contemporary

Willemstad Private Full-Day Curaçao Island Tour with Local Expert
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park

See the whole trip →

Willemstad

7-night Panama Canal from Cartagena

Royal Caribbean · Grandeur of the Seas

5 ports
Round trip
Sails Mar 14, 2027
From $1,444 pp
Contemporary

Willemstad Private Full-Day Curaçao Island Tour with Local Expert
Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ

See the whole trip →

Port of Oranjestad

7-night Panama Canal from Cartagena

Royal Caribbean · Grandeur of the Seas

5 ports
Round trip
Sails Apr 11, 2027
From $1,603 pp
Contemporary

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park
Willemstad Private Full-Day Curaçao Island Tour with Local Expert

See the whole trip →

Kralendijk

7-night Panama Canal from Cartagena

Royal Caribbean · Grandeur of the Seas

5 ports
Round trip
Sails Apr 2, 2028
From $974 pp
Contemporary

Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Willemstad Private Full-Day Curaçao Island Tour with Local Expert

See the whole trip →

Port of Oranjestad

7-night Panama Canal from Cartagena

Royal Caribbean · Grandeur of the Seas

4 ports
Round trip
Sails Dec 20, 2026
From $1,926 pp
Contemporary

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

See the whole trip →

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