⚓ Cruises

Royal Caribbean Caribbean cruises from Colon

8 itineraries with a bookable sailing ahead, 11 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › Royal Caribbean Caribbean cruises from Colon

Most popular first

Ranked by what people search for and where the cruise lines send the most ships.

Cartagena

7-night Caribbean from Colon

Royal Caribbean · Grandeur of the Seas

4 ports
Round trip
4 departures Oct 2026 – Feb 2028
From $827 pp
Contemporary

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Willemstad Private Full-Day Curaçao Island Tour with Local Expert

See the whole trip →

Port of Kingstown

7-night Colon to San Juan

Royal Caribbean · Grandeur of the Seas

6 ports
One way
Sails Apr 24, 2027
From $497 pp
Contemporary

Port of Kingstown La Soufrière Volcano Summit Hike: St. Vincent's Crown
Castries Cosol Tours: All-Island Private Safari with 7 Stops
St. John's Private Half-Day Island Adventure & Trunk Bay Beach

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Cartagena

7-night Caribbean from Colon

Royal Caribbean · Grandeur of the Seas

4 ports
Round trip
Sails Dec 26, 2026
From $2,477 pp
Contemporary

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Willemstad Private Full-Day Curaçao Island Tour with Local Expert

See the whole trip →

Cartagena

7-night Caribbean from Colon

Royal Caribbean · Grandeur of the Seas

5 ports
Round trip
Sails Jan 23, 2027
From $1,133 pp
Contemporary

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park
Willemstad Private Full-Day Curaçao Island Tour with Local Expert

See the whole trip →

Cartagena

7-night Caribbean from Colon

Royal Caribbean · Grandeur of the Seas

5 ports
Round trip
Sails Jan 30, 2027
From $1,181 pp
Contemporary

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Willemstad Private Full-Day Curaçao Island Tour with Local Expert
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ

See the whole trip →

Cartagena

7-night Caribbean from Colon

Royal Caribbean · Grandeur of the Seas

5 ports
Round trip
Sails Mar 27, 2027
From $1,287 pp
Contemporary

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Willemstad Private Full-Day Curaçao Island Tour with Local Expert
Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park

See the whole trip →

Cartagena

7-night Caribbean from Colon

Royal Caribbean · Grandeur of the Seas

5 ports
Round trip
Sails Apr 10, 2027
From $1,333 pp
Contemporary

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park

See the whole trip →

Cartagena

7-night Caribbean from Colon

Royal Caribbean · Grandeur of the Seas

4 ports
Round trip
Sails Feb 13, 2027
From $1,105 pp
Contemporary

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park

See the whole trip →

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