⚓ Cruises

Holland America Panama Canal cruises

6 itineraries with a bookable sailing ahead, 6 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › Holland America Panama Canal cruises

Sailing from

Fort Lauderdale (Port Everglades)3 San Antonio2 San Diego1

Most popular first

Ranked by what people search for and where the cruise lines send the most ships.

Port of Oranjestad

21-night Fort Lauderdale (Port Everglades) to Vancouver

Holland America · Oosterdam

11 ports
Repositioning
Sails Apr 7, 2028
From $3,434 pp
Premium

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Panama Canal Panama Canal Full Transit: Pacific to Atlantic by Boat
Puntarenas Monteverde Cloud Forest: Private Guided Reserve Walk & Hanging Bridges

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Half Moon Cay (Little San Salvador Island)

21-night Panama Canal from Fort Lauderdale (Port Everglades)

Holland America · Oosterdam

11 ports
Round trip
Sails Feb 13, 2028
From $3,654 pp
Premium

Half Moon Cay (Little San Salvador Island) Horseback Riding by Land & Sea (Pegasus Ranch)
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach

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Half Moon Cay (Little San Salvador Island)

21-night Panama Canal from Fort Lauderdale (Port Everglades)

Holland America · Oosterdam

11 ports
Round trip
Sails Mar 5, 2028
From $3,554 pp
Premium

Half Moon Cay (Little San Salvador Island) Horseback Riding by Land & Sea (Pegasus Ranch)
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach

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Cabo San Lucas

15-night San Diego to Fort Lauderdale (Port Everglades)

Holland America · Zaandam

9 ports
One way
Sails Dec 19, 2026
From $1,799 pp
Premium

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel
Huatulco Copalitilla Magic Waterfalls: Private Expert-Led Jungle Trek

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Coquimbo (La Serena)

16-night San Antonio to Fort Lauderdale (Port Everglades)

Holland America · Oosterdam

10 ports
One way
Sails Mar 24, 2027
From $2,299 pp
Premium

Coquimbo (La Serena) Elqui Valley: Pisco Distillery, Vineyards & Stargazing
General San Martin Ballestas Islands: Private Wildlife Boat Expedition
Callao (Lima) Palomino Islands: Swim with Sea Lions in the Pacific

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Coquimbo (La Serena)

17-night San Antonio to Fort Lauderdale (Port Everglades)

Holland America · Nieuw Amsterdam

10 ports
One way
Sails Mar 21, 2028
From $2,894 pp
Premium

Coquimbo (La Serena) Elqui Valley: Pisco Distillery, Vineyards & Stargazing
General San Martin Ballestas Islands: Private Wildlife Boat Expedition
Callao (Lima) Palomino Islands: Swim with Sea Lions in the Pacific

See the whole trip →

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