⚓ Cruises

Regent South America cruises

3 itineraries with a bookable sailing ahead, 3 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › Regent South America cruises

Sailing from

Buenos Aires2 Rio de Janeiro1

Most popular first

Ranked by what people search for and where the cruise lines send the most ships.

Buzios

11-night Rio de Janeiro to Buenos Aires

Regent · Seven Seas Mariner

10 ports
One way
Sails Jan 22, 2027
From $13,199 pp
Luxury

Buzios Private Catamaran Cruise: Buzios' 20 Beaches & Hidden Coves
Ilha Grande Lopes Mendes Beach: Private Speedboat & Jungle Trail
Ilhabela Private Superboat to Castelhanos & Hidden Atlantic Forest Beaches

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Willis Island

18-night South America from Buenos Aires

Regent · Seven Seas Mariner

8 ports
Round trip
Sails Feb 2, 2027
From $15,899 pp
Luxury

Willis Island Zodiac Circumnavigation of Willis Island: Seabirds & Reef
Puerto Madryn Private Full-Day Península Valdés: Orcas, Elephants & Sea Lions
Punta Arenas Full-Day King Penguin Colony & Tierra del Fuego Expedition

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Willis Island

18-night Buenos Aires to Lima

Regent · Seven Seas Mariner

8 ports
One way
Sails Feb 20, 2027
From $16,149 pp
Luxury

Willis Island Zodiac Circumnavigation of Willis Island: Seabirds & Reef
Port Stanley Bertha's Beach Private 4×4 Gentoo Penguin Expedition
Ushuaia Isla Martillo: Private Penguin Colony Landing

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Prefer a calendar? →The ports themselves →