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Filtering From Genoa, Italy ×13+ nights ×9–12 nights × Clear all
Showing 36 of 52 sailings
MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Jun 22 – Jul 2, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,348
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Jul 2 – Jul 12, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,079
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Jul 12 – Jul 22, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,358
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Jul 22 – Aug 1, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,435
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Aug 1 – Aug 11, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,874
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Aug 11 – Aug 21, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $2,119
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Aug 21 – Aug 31, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $2,065
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Aug 31 – Sep 10, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,791
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Sep 10 – Sep 20, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,666
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Sep 20 – Sep 30, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,503
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Sep 30 – Oct 10, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,658
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MSC Cruises · MSC GrandiosaRepositioning
Mediterranean 19 nights Oct 26 – Nov 14, 2026 from Genoa, Italy to Port Canaveral, Florida
Genoa, Italy · La Spezia (Cinque Terre), Italy · … · Port Canaveral, Florida9 ports
Genoa, Italy · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy · Palma de Mallorca, Spain · Barcelona, Spain · Funchal, Madeira, Portugal · San Juan, Puerto Rico · Miami, Florida · Port Canaveral, Florida
★ Bucket-list Sail straight to Portofino from the cruise dockPrivate Cinque Terre by Minivan & Ferryboat from L…Vatican, Sistine Chapel & Colosseum in One DayLa Seu Cathedral + Rooftop Terraces Climb +5 more
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from $983
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MSC Cruises · MSC OperaRepositioning
Mediterranean 17 nights Oct 30 – Nov 16, 2026 from Genoa, Italy to La Romana, Dominican Republic
Genoa, Italy · Livorno (Florence/Pisa), Italy · … · La Romana, Dominican Republic9 ports
Genoa, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · Tangier, Morocco · St. John's, Antigua · Philipsburg, St. Maarten · Port of Charlestown, Nevis, St. Kitts and Nevis · La Romana, Dominican Republic
★ Bucket-list Sail straight to Portofino from the cruise dockClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada Familia +5 more
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from $1,246
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MSC Cruises · MSC DivinaRepositioning
Mediterranean 16 nights Oct 31 – Nov 16, 2026 from Genoa, Italy to Santos (Sao Paulo), Brazil
Genoa, Italy · Tarragona, Spain · … · Santos (Sao Paulo), Brazil6 ports
Genoa, Italy · Tarragona, Spain · Santa Cruz de Tenerife, Canary Islands · Bahia de Salvador, Brazil · Rio de Janeiro, Brazil · Santos (Sao Paulo), Brazil
★ Bucket-list Sail straight to Portofino from the cruise dockPrivate Roman TarracoTeide National ParkPelourinho Private Walking Tour with Ivan Bahia Gu… +2 more
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from $1,202
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MSC Cruises · MSC World EuropaRepositioning
Caribbean 21 nights Nov 14 – Dec 5, 2026 from Genoa, Italy to Fort-de-France, Martinique
Genoa, Italy · Civitavecchia (Rome), Italy · … · Fort-de-France, Martinique13 ports
Genoa, Italy · Civitavecchia (Rome), Italy · La Spezia (Cinque Terre), Italy · Marseille, France · Barcelona, Spain · Puerto del Rosario, Spain · Santa Cruz de Tenerife, Canary Islands · Philipsburg, St. Maarten · Port of Charlestown, Nevis, St. Kitts and Nevis · Port of Kingstown, St. Vincent & the Grenadines · Bridgetown, Barbados · St. Georges, Grenada, West Indies · Fort-de-France, Martinique
★ Bucket-list Sail straight to Portofino from the cruise dockVatican, Sistine Chapel & Colosseum in One DayPrivate Cinque Terre by Minivan & Ferryboat from L…Calanques National Park Boat Cruise from the Old P… +9 more
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from $1,223
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MSC Cruises · MSC MagnificaRound-trip
Mediterranean 10 nights Dec 6 – Dec 16, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Barcelona, Spain · Cadiz (Seville), Spain · Casablanca, Morocco · Malaga, Spain · Alicante, Spain · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaReal Alcázar de Sevilla +4 more
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from $1,087
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MSC Cruises · MSC MagnificaRound-trip
Mediterranean 10 nights Dec 16 – Dec 26, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Barcelona, Spain · Cadiz (Seville), Spain · Casablanca, Morocco · Malaga, Spain · Alicante, Spain · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaReal Alcázar de Sevilla +4 more
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from $1,348
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MSC Cruises · MSC MagnificaRound-trip
Mediterranean 10 nights Dec 26 – Jan 5, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy8 ports
Genoa, Italy · Marseille, France · Barcelona, Spain · Cadiz (Seville), Spain · Malaga, Spain · Alicante, Spain · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaReal Alcázar de Sevilla +3 more
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from $2,036
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 12 nights Apr 6 – Apr 18, 2027 from Genoa, Italy
Genoa, Italy · Livorno (Florence/Pisa), Italy · … · Genoa, Italy10 ports
Genoa, Italy · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Valencia, Spain · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Valencia, Spain · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One DayOceanografic +2 more
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from $1,332
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MSC Cruises · MSC EuribiaOne-way
Mediterranean 12 nights Apr 12 – Apr 24, 2027 from Genoa, Italy to Kiel, Germany
Genoa, Italy · Barcelona, Spain · … · Kiel, Germany9 ports
Genoa, Italy · Barcelona, Spain · Alicante, Spain · Gibraltar, British Territory · Cadiz (Seville), Spain · La Coruna, Spain · Bilbao, Spain · La Rochelle, France · Kiel, Germany
★ Bucket-list Sail straight to Portofino from the cruise dockSagrada FamiliaCastillo de Santa BárbaraUpper Rock Nature Reserve +5 more
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from $1,248
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Apr 18 – Apr 28, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Tangier, Morocco · Portimao, Portugal · Ceuta, Spain · Alicante, Spain · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraTangier Kasbah, Medina & American Legation Private… +4 more
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from $1,562
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Apr 28 – May 8, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Tangier, Morocco · Portimao, Portugal · Ceuta, Spain · Alicante, Spain · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraTangier Kasbah, Medina & American Legation Private… +4 more
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from $1,662
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Seabourn · Seabourn OvationOne-way
Mediterranean 29 nights Apr 30 – May 29, 2027 from Genoa, Italy to Istanbul, Turkey
Genoa, Italy · Portovenere, Italy · … · Istanbul, Turkey26 ports
Genoa, Italy · Portovenere, Italy · Bonifacio, Corsica, France · Cagliari, Sardinia, Italy · La Goulette, Tunisia · Trapani, Italy · Palermo, Sicily, Italy · Civitavecchia (Rome), Italy · Salerno, Italy · Giardini Naxos, Sicily · Valletta, Malta · Korcula, Croatia · Kotor, Montenegro · Dubrovnik, Croatia · Kotor, Montenegro · Brindisi, Italy · Corfu, Greece · Delphi, Greece · Gythion, Greece · Piraeus (Athens), Greece · Monemvasia, Greece · Crete, Greece · Mykonos, Greece · Cesme, turkey · Kusadasi (Ephesus), Turkey · Istanbul, Turkey
★ Bucket-list Sail straight to Portofino from the cruise dockPrivate Boat CharterLavezzi IslandsSu Nuraxi di Barumini +21 more
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from $26,434
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MSC Cruises · MSC MagnificaOne-way
Mediterranean 11 nights May 6 – May 17, 2027 from Genoa, Italy to Warnemunde, Germany
Genoa, Italy · Marseille, France · … · Warnemunde, Germany8 ports
Genoa, Italy · Marseille, France · Tarragona, Spain · La Coruna, Spain · Bilbao, Spain · La Rochelle, France · Brest, France · Warnemunde, Germany
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Private Roman TarracoSantiago de Compostela +4 more
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from $1,204
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights May 8 – May 18, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Casablanca, Morocco · Cadiz (Seville), Spain · Gibraltar, British Territory · Alicante, Spain · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraPrivate Guided Tour of Casablanca with Hassan II M… +4 more
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from $1,662
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights May 18 – May 28, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Tangier, Morocco · Portimao, Portugal · Ceuta, Spain · Alicante, Spain · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraTangier Kasbah, Medina & American Legation Private… +4 more
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from $1,662
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights May 28 – Jun 7, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,642
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Jun 7 – Jun 17, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,702
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Jun 17 – Jun 27, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Portimao, Portugal · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraPrivate Benagil Cave Boat Tour +4 more
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from $1,782
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Jun 27 – Jul 7, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Portimao, Portugal · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraPrivate Benagil Cave Boat Tour +4 more
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from $1,782
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Jul 7 – Jul 17, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,842
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Jul 17 – Jul 27, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,912
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Jul 27 – Aug 6, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,942
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Aug 6 – Aug 16, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Portimao, Portugal · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraPrivate Benagil Cave Boat Tour +4 more
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from $2,092
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Aug 16 – Aug 26, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,992
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Aug 26 – Sep 5, 2027 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports
Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Granada & the AlhambraReal Alcázar de Sevilla +4 more
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from $1,842
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Itineraries from the Cruisebound catalog + our enrichment; schedules cross-checked against official port authorities. Booking via Cruisebound and CruiseDirect — we may earn a commission, at no extra cost to you.

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MSC Cruises Royal Caribbean Carnival Viking River Costa Norwegian AmaWaterways Princess Celebrity Viking Ocean Avalon Disney Holland America Oceania Virgin Voyages Regent Cunard Seabourn Azamara