Bucket-List Cruise Adventures

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Bucket-list adventures at every port — where to fly in, and what to do the day(s) before and after.

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Filtering MSC Cruises ×Royal Caribbean ×From San Diego, California × Clear all
Showing 36 of 49 sailings
Royal Caribbean · Serenade of the SeasRound-trip
Mexico 2 nights Oct 2 – Oct 4, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $317
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MSC Cruises · MSC PoesiaRepositioning
Caribbean 14 nights Oct 3 – Oct 17, 2026 from San Diego, California to Miami, Florida
San Diego, California · Cabo San Lucas, Mexico · … · Miami, Florida6 ports
San Diego, California · Cabo San Lucas, Mexico · Puntarenas, Costa Rica · Colon, Panama · Cartagena, Colombia · Miami, Florida
★ Bucket-list San Diego ZooEl Arco & Lover's BeachMonteverde Cloud ForestPanama Canal Full Transit +2 more
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from $1,056
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Oct 4 – Oct 11, 2026 from San Diego, California
San Diego, California · La Paz, Mexico · Cabo San Lucas, Mexico · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooWhale Shark SnorkelEl Arco & Lover's BeachValle de Guadalupe wine country
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from $489
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 4 nights Oct 11 – Oct 15, 2026 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
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from $304
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 3 nights Oct 15 – Oct 18, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $276
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Oct 18 – Oct 25, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · Cabo San Lucas, Mexico · La Paz, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine countryEl Arco & Lover's BeachWhale Shark Snorkel
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from $527
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Oct 25 – Nov 1, 2026 from San Diego, California
San Diego, California · La Paz, Mexico · Cabo San Lucas, Mexico · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooWhale Shark SnorkelEl Arco & Lover's BeachValle de Guadalupe wine country
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from $469
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Nov 1 – Nov 8, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · Cabo San Lucas, Mexico · Mazatlan, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine countryEl Arco & Lover's BeachIsla de Venados
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from $460
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Nov 8 – Nov 15, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · Cabo San Lucas, Mexico · Mazatlan, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine countryEl Arco & Lover's BeachIsla de Venados
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from $459
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Nov 15 – Nov 22, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · Cabo San Lucas, Mexico · La Paz, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine countryEl Arco & Lover's BeachWhale Shark Snorkel
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from $373
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Nov 22 – Nov 29, 2026 from San Diego, California
San Diego, California · Cabo San Lucas, Mexico · La Paz, Mexico · Mazatlan, Mexico · San Diego, California
★ Bucket-list San Diego ZooEl Arco & Lover's BeachWhale Shark SnorkelIsla de Venados
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from $727
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 4 nights Nov 29 – Dec 3, 2026 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
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from $347
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 3 nights Dec 3 – Dec 6, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $317
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 4 nights Dec 6 – Dec 10, 2026 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
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from $295
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 3 nights Dec 10 – Dec 13, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $298
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico Dec 13, 2026 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · Cabo San Lucas, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine countryEl Arco & Lover's Beach
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from $485
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Dec 20 – Dec 27, 2026 from San Diego, California
San Diego, California · Cabo San Lucas, Mexico · La Paz, Mexico · Mazatlan, Mexico · San Diego, California
★ Bucket-list San Diego ZooEl Arco & Lover's BeachWhale Shark SnorkelIsla de Venados
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from $512
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Dec 27 – Jan 3, 2027 from San Diego, California
San Diego, California · Mazatlan, Mexico · La Paz, Mexico · Cabo San Lucas, Mexico · San Diego, California
★ Bucket-list San Diego ZooIsla de VenadosWhale Shark SnorkelEl Arco & Lover's Beach
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from $958
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Jan 3 – Jan 10, 2027 from San Diego, California
San Diego, California · La Paz, Mexico · Cabo San Lucas, Mexico · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooWhale Shark SnorkelEl Arco & Lover's BeachValle de Guadalupe wine country
View →
from $522
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 4 nights Jan 10 – Jan 14, 2027 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
View →
from $358
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 3 nights Jan 14 – Jan 17, 2027 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $238
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 4 nights Jan 17 – Jan 21, 2027 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
View →
from $365
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 3 nights Jan 21 – Jan 24, 2027 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $316
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 4 nights Jan 24 – Jan 28, 2027 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
View →
from $307
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Jan 28 – Feb 4, 2027 from San Diego, California
San Diego, California · Cabo San Lucas, Mexico · Mazatlan, Mexico · La Paz, Mexico · San Diego, California
★ Bucket-list San Diego ZooEl Arco & Lover's BeachIsla de VenadosWhale Shark Snorkel
View →
from $505
Book This Cruise@ Cruisebound
Royal Caribbean · Serenade of the SeasRound-trip
Mexico 3 nights Feb 4 – Feb 7, 2027 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
View →
from $336
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 4 nights Feb 7 – Feb 11, 2027 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
View →
from $380
Book This Cruise@ Cruisebound
Royal Caribbean · Serenade of the SeasRound-trip
Mexico 3 nights Feb 11 – Feb 14, 2027 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
View →
from $336
Book This Cruise@ Cruisebound
Royal Caribbean · Serenade of the SeasRound-trip
Mexico 4 nights Feb 14 – Feb 18, 2027 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
View →
from $370
Book This Cruise@ Cruisebound
Royal Caribbean · Serenade of the SeasRound-trip
Mexico 3 nights Feb 18 – Feb 21, 2027 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
View →
from $349
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 4 nights Feb 21 – Feb 25, 2027 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
View →
from $399
Book This Cruise@ Cruisebound
Royal Caribbean · Serenade of the SeasRound-trip
Mexico 3 nights Feb 25 – Feb 28, 2027 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
View →
from $349
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Feb 28 – Mar 7, 2027 from San Diego, California
San Diego, California · Ensenada, Mexico · Cabo San Lucas, Mexico · Mazatlan, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine countryEl Arco & Lover's BeachIsla de Venados
View →
from $527
Book This Cruise@ Cruisebound
Royal Caribbean · Serenade of the SeasRound-trip
Mexico 4 nights Mar 7 – Mar 11, 2027 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
View →
from $399
Book This Cruise@ Cruisebound
Royal Caribbean · Serenade of the SeasRound-trip
Mexico 3 nights Mar 11 – Mar 14, 2027 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
View →
from $349
Book This Cruise@ Cruisebound
Royal Caribbean · Serenade of the SeasRound-trip
Mexico 4 nights Mar 14 – Mar 18, 2027 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
View →
from $379
Book This Cruise@ Cruisebound
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Itineraries from the Cruisebound catalog + our enrichment; schedules cross-checked against official port authorities. Booking via Cruisebound and CruiseDirect — we may earn a commission, at no extra cost to you.

19 lines
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MSC Cruises Royal Caribbean Carnival Viking River Costa Norwegian AmaWaterways Princess Celebrity Viking Ocean Avalon Disney Holland America Oceania Virgin Voyages Regent Cunard Seabourn Azamara