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Showing 36 of 127 sailings

MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Jul 15 – Jul 25, 2026 from Malaga, Spain

Malaga, Spain · Cadiz (Seville), Spain · … · Malaga, Spain9 ports

Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain

★ Bucket-list Granada & the Alhambra Real Alcázar de Sevilla Sintra Castillo de Santa Bárbara +4 more

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from $1,582

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Jul 17 – Jul 27, 2026 from Lisbon, Portugal

Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports

Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal

★ Bucket-list Sintra Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island +4 more

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from $1,462

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Jul 19 – Jul 29, 2026 from Alicante, Spain

Alicante, Spain · Mahon, Minorca, Spain · … · Alicante, Spain9 ports

Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain

★ Bucket-list Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island Sail straight to Portofino from the cruise dock +4 more

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from $1,285

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Jul 22 – Aug 1, 2026 from Genoa, Italy

Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports

Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy

★ Bucket-list Sail straight to Portofino from the cruise dock Calanques National Park Boat Cruise from the Old P…Granada & the Alhambra Real Alcázar de Sevilla +4 more

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from $1,435

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Jul 25 – Aug 4, 2026 from Malaga, Spain

Malaga, Spain · Cadiz (Seville), Spain · … · Malaga, Spain9 ports

Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain

★ Bucket-list Granada & the Alhambra Real Alcázar de Sevilla Sintra Castillo de Santa Bárbara +4 more

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from $1,402

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MSC Cruises · MSC VirtuosaRound-trip

Mediterranean 14 nights Jul 25 – Aug 8, 2026 from Southampton, England

Southampton, England · La Coruna, Spain · … · Southampton, England10 ports

Southampton, England · La Coruna, Spain · Cadiz (Seville), Spain · Malaga, Spain · Alicante, Spain · Ibiza, Spain · Tarragona, Spain · Gibraltar, British Territory · Lisbon, Portugal · Southampton, England

★ Bucket-list Stand Inside Stonehenge & See the Original 1215 Ma…Santiago de Compostela Real Alcázar de Sevilla Granada & the Alhambra +5 more

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from $1,701

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Jul 27 – Aug 6, 2026 from Lisbon, Portugal

Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports

Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal

★ Bucket-list Sintra Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island +4 more

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from $1,077

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Jul 29 – Aug 8, 2026 from Alicante, Spain

Alicante, Spain · Mahon, Minorca, Spain · … · Alicante, Spain9 ports

Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain

★ Bucket-list Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island Sail straight to Portofino from the cruise dock +4 more

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from $1,708

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 1 – Aug 11, 2026 from Genoa, Italy

Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports

Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy

★ Bucket-list Sail straight to Portofino from the cruise dock Calanques National Park Boat Cruise from the Old P…Granada & the Alhambra Real Alcázar de Sevilla +4 more

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from $1,874

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 2 – Aug 12, 2026 from Marseille, France

Marseille, France · Malaga, Spain · … · Marseille, France9 ports

Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France

★ Bucket-list Calanques National Park Boat Cruise from the Old P…Granada & the Alhambra Real Alcázar de Sevilla Sintra +4 more

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from $1,743

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 4 – Aug 14, 2026 from Malaga, Spain

Malaga, Spain · Cadiz (Seville), Spain · … · Malaga, Spain9 ports

Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain

★ Bucket-list Granada & the Alhambra Real Alcázar de Sevilla Sintra Castillo de Santa Bárbara +4 more

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from $1,740

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 6 – Aug 16, 2026 from Lisbon, Portugal

Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports

Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal

★ Bucket-list Sintra Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island +4 more

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from $1,531

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 8 – Aug 18, 2026 from Alicante, Spain

Alicante, Spain · Mahon, Minorca, Spain · … · Alicante, Spain9 ports

Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain

★ Bucket-list Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island Sail straight to Portofino from the cruise dock +4 more

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from $1,753

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 11 – Aug 21, 2026 from Genoa, Italy

Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports

Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy

★ Bucket-list Sail straight to Portofino from the cruise dock Calanques National Park Boat Cruise from the Old P…Granada & the Alhambra Real Alcázar de Sevilla +4 more

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from $2,119

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 12 – Aug 22, 2026 from Marseille, France

Marseille, France · Malaga, Spain · … · Marseille, France9 ports

Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France

★ Bucket-list Calanques National Park Boat Cruise from the Old P…Granada & the Alhambra Real Alcázar de Sevilla Sintra +4 more

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from $1,712

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 14 – Aug 24, 2026 from Malaga, Spain

Malaga, Spain · Cadiz (Seville), Spain · … · Malaga, Spain9 ports

Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain

★ Bucket-list Granada & the Alhambra Real Alcázar de Sevilla Sintra Castillo de Santa Bárbara +4 more

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from $1,916

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 16 – Aug 26, 2026 from Lisbon, Portugal

Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports

Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal

★ Bucket-list Sintra Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island +4 more

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from $1,737

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 18 – Aug 28, 2026 from Alicante, Spain

Alicante, Spain · Mahon, Minorca, Spain · … · Alicante, Spain9 ports

Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain

★ Bucket-list Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island Sail straight to Portofino from the cruise dock +4 more

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from $1,461

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MSC Cruises · MSC VirtuosaRound-trip

Mediterranean 9 nights Aug 20 – Aug 29, 2026 from Southampton, England

Southampton, England · Brest, France · … · Southampton, England7 ports

Southampton, England · Brest, France · Lisbon, Portugal · Gibraltar, British Territory · Malaga, Spain · Cadiz (Seville), Spain · Southampton, England

★ Bucket-list Stand Inside Stonehenge & See the Original 1215 Ma…Private Shore Excursion Sintra Upper Rock Nature Reserve +2 more

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from $1,380

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 21 – Aug 31, 2026 from Genoa, Italy

Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports

Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy

★ Bucket-list Sail straight to Portofino from the cruise dock Calanques National Park Boat Cruise from the Old P…Granada & the Alhambra Real Alcázar de Sevilla +4 more

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from $2,065

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 22 – Sep 1, 2026 from Marseille, France

Marseille, France · Malaga, Spain · … · Marseille, France9 ports

Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France

★ Bucket-list Calanques National Park Boat Cruise from the Old P…Granada & the Alhambra Real Alcázar de Sevilla Sintra +4 more

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from $1,694

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 24 – Sep 3, 2026 from Malaga, Spain

Malaga, Spain · Cadiz (Seville), Spain · … · Malaga, Spain9 ports

Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain

★ Bucket-list Granada & the Alhambra Real Alcázar de Sevilla Sintra Castillo de Santa Bárbara +4 more

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from $1,560

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 26 – Sep 5, 2026 from Lisbon, Portugal

Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports

Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal

★ Bucket-list Sintra Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island +4 more

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from $1,717

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 28 – Sep 7, 2026 from Alicante, Spain

Alicante, Spain · Mahon, Minorca, Spain · … · Alicante, Spain9 ports

Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain

★ Bucket-list Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island Sail straight to Portofino from the cruise dock +4 more

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from $1,411

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Aug 31 – Sep 10, 2026 from Genoa, Italy

Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports

Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy

★ Bucket-list Sail straight to Portofino from the cruise dock Calanques National Park Boat Cruise from the Old P…Granada & the Alhambra Real Alcázar de Sevilla +4 more

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from $1,791

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Sep 1 – Sep 11, 2026 from Marseille, France

Marseille, France · Malaga, Spain · … · Marseille, France9 ports

Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France

★ Bucket-list Calanques National Park Boat Cruise from the Old P…Granada & the Alhambra Real Alcázar de Sevilla Sintra +4 more

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from $1,447

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Sep 3 – Sep 13, 2026 from Malaga, Spain

Malaga, Spain · Cadiz (Seville), Spain · … · Malaga, Spain9 ports

Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain

★ Bucket-list Granada & the Alhambra Real Alcázar de Sevilla Sintra Castillo de Santa Bárbara +4 more

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from $1,873

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Sep 5 – Sep 15, 2026 from Lisbon, Portugal

Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports

Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal

★ Bucket-list Sintra Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island +4 more

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from $1,447

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Sep 7 – Sep 17, 2026 from Alicante, Spain

Alicante, Spain · Mahon, Minorca, Spain · … · Alicante, Spain9 ports

Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain

★ Bucket-list Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island Sail straight to Portofino from the cruise dock +4 more

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from $1,562

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Sep 10 – Sep 20, 2026 from Genoa, Italy

Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports

Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy

★ Bucket-list Sail straight to Portofino from the cruise dock Calanques National Park Boat Cruise from the Old P…Granada & the Alhambra Real Alcázar de Sevilla +4 more

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from $1,666

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Sep 11 – Sep 21, 2026 from Marseille, France

Marseille, France · Malaga, Spain · … · Marseille, France9 ports

Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France

★ Bucket-list Calanques National Park Boat Cruise from the Old P…Granada & the Alhambra Real Alcázar de Sevilla Sintra +4 more

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from $1,554

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MSC Cruises · MSC VirtuosaRound-trip

Mediterranean 14 nights Sep 12 – Sep 26, 2026 from Southampton, England

Southampton, England · Lisbon, Portugal · … · Southampton, England10 ports

Southampton, England · Lisbon, Portugal · Cadiz (Seville), Spain · Malaga, Spain · Alicante, Spain · Palma de Mallorca, Spain · Tarragona, Spain · Gibraltar, British Territory · La Coruna, Spain · Southampton, England

★ Bucket-list Stand Inside Stonehenge & See the Original 1215 Ma…Sintra Real Alcázar de Sevilla Granada & the Alhambra +5 more

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from $1,472

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Sep 13 – Sep 23, 2026 from Malaga, Spain

Malaga, Spain · Cadiz (Seville), Spain · … · Malaga, Spain9 ports

Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain

★ Bucket-list Granada & the Alhambra Real Alcázar de Sevilla Sintra Castillo de Santa Bárbara +4 more

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from $2,042

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Sep 15 – Sep 25, 2026 from Lisbon, Portugal

Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports

Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal

★ Bucket-list Sintra Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island +4 more

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from $1,607

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Sep 17 – Sep 27, 2026 from Alicante, Spain

Alicante, Spain · Mahon, Minorca, Spain · … · Alicante, Spain9 ports

Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain

★ Bucket-list Castillo de Santa Bárbara Private Catamaran Sail Tavolara Island Sail straight to Portofino from the cruise dock +4 more

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from $1,596

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MSC Cruises · MSC OperaRound-trip

Mediterranean 10 nights Sep 20 – Sep 30, 2026 from Genoa, Italy

Genoa, Italy · Marseille, France · … · Genoa, Italy9 ports

Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy

★ Bucket-list Sail straight to Portofino from the cruise dock Calanques National Park Boat Cruise from the Old P…Granada & the Alhambra Real Alcázar de Sevilla +4 more

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from $1,503

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Itineraries from the Cruisebound catalog + our enrichment; schedules cross-checked against official port authorities. Booking via Cruisebound and CruiseDirect — we may earn a commission, at no extra cost to you.

19 lines
aboard

MSC Cruises Royal Caribbean Carnival Viking River Costa Norwegian AmaWaterways Princess Celebrity Viking Ocean Avalon Disney Holland America Oceania Virgin Voyages Regent Cunard Seabourn Azamara