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Showing 72 of 1,498 sailings
MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 17 – Sep 24, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Valletta, Malta · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,305
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Costa · Costa FascinosaRound-trip
Mediterranean 15 nights Sep 18 – Oct 3, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Ajaccio, Corsica, France · … · Civitavecchia (Rome), Italy13 ports
Civitavecchia (Rome), Italy · Ajaccio, Corsica, France · Savona (Genoa), Italy · Marseille, France · Barcelona, Spain · Palma de Mallorca, Spain · Valletta, Malta · Santorini (Thira), Greece · Mykonos, Greece · Piraeus (Athens), Greece · Souda Bay · Messina, Sicily, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySanguinaires Islands & CalanquesPortofino & San Fruttuoso Abbey by the local ferryCalanques National Park Boat Cruise from the Old P… +8 more
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from $1,927
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +2 more
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from $1,745
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed Archaeologist +2 more
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from $1,382
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 19 – Sep 26, 2026 from Marseille, France
Marseille, France · Genoa, Italy · … · Marseille, France7 ports
Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount… +2 more
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from $3,813
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Costa · Costa FascinosaRound-trip
Mediterranean 14 nights Sep 20 – Oct 4, 2026 from Savona (Genoa), Italy
Savona (Genoa), Italy · Marseille, France · … · Savona (Genoa), Italy12 ports
Savona (Genoa), Italy · Marseille, France · Barcelona, Spain · Palma de Mallorca, Spain · Valletta, Malta · Santorini (Thira), Greece · Mykonos, Greece · Piraeus (Athens), Greece · Souda Bay · Messina, Sicily, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy
★ Bucket-list Portofino & San Fruttuoso Abbey by the local ferryCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaLa Seu Cathedral + Rooftop Terraces Climb +7 more
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from $1,457
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di Barumini +2 more
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from $2,026
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Genoa, Italy
Genoa, Italy · Naples, Italy · … · Genoa, Italy7 ports
Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $4,232
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Oceania · Oceania SirenaOne-way
Mediterranean 10 nights Sep 20 – Sep 30, 2026 from Valletta, Malta to Barcelona, Spain
Valletta, Malta · Catania, Sicily, Italy · … · Barcelona, Spain11 ports
Valletta, Malta · Catania, Sicily, Italy · Sorrento, Italy · Civitavecchia (Rome), Italy · Olbia, Italy · Portofino, Italy · Villefranche, France · Marseille, France · Port Vendres (Carcassonne), France · Palma de Mallorca, Spain · Barcelona, Spain
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesMount Etna Private Jeep Summit Tour from Catania P…Pompeii Private Excavation Tour with Archaeologist…Vatican, Sistine Chapel & Colosseum in One Day +7 more
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from $3,749
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Costa · Costa FascinosaRound-trip
Mediterranean 16 nights Sep 21 – Oct 7, 2026 from Marseille, France
Marseille, France · Barcelona, Spain · … · Marseille, France13 ports
Marseille, France · Barcelona, Spain · Palma de Mallorca, Spain · Valletta, Malta · Santorini (Thira), Greece · Mykonos, Greece · Piraeus (Athens), Greece · Souda Bay · Messina, Sicily, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaLa Seu Cathedral + Rooftop Terraces ClimbSt John's Co-Cathedral & the Caravaggio masterpieces +7 more
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from $2,179
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 21 – Sep 28, 2026 from Marseille, France
Marseille, France · Livorno (Florence/Pisa), Italy · … · Marseille, France7 ports
Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman Palace +2 more
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from $1,277
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 21 – Sep 28, 2026 from Naples, Italy
Naples, Italy · Messina, Sicily, Italy · … · Naples, Italy7 ports
Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,237
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Costa · Costa FascinosaRound-trip
Mediterranean 14 nights Sep 22 – Oct 6, 2026 from Barcelona, Spain
Barcelona, Spain · Palma de Mallorca, Spain · … · Barcelona, Spain11 ports
Barcelona, Spain · Palma de Mallorca, Spain · Valletta, Malta · Santorini (Thira), Greece · Mykonos, Greece · Piraeus (Athens), Greece · Souda Bay · Messina, Sicily, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Barcelona, Spain
★ Bucket-list Sagrada FamiliaLa Seu Cathedral + Rooftop Terraces ClimbSt John's Co-Cathedral & the Caravaggio masterpiecesSemi-Private Caldera Catamaran with Hot Springs &… +6 more
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from $2,231
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 22 – Sep 29, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,153
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 22 – Sep 29, 2026 from Messina, Sicily, Italy
Messina, Sicily, Italy · Valletta, Malta · … · Messina, Sicily, Italy7 ports
Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy
★ Bucket-list Taormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,871
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 23 – Sep 30, 2026 from Cagliari, Sardinia, Italy
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · … · Cagliari, Sardinia, Italy7 ports
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy
★ Bucket-list Su Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,363
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 23 – Sep 30, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dock +2 more
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from $1,886
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 24 – Oct 1, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Valletta, Malta · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $2,094
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +2 more
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from $2,094
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed Archaeologist +2 more
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from $1,112
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Princess · Enchanted PrincessOne-way
Mediterranean 11 nights Sep 25 – Oct 6, 2026 from Piraeus (Athens), Greece to Civitavecchia (Rome), Italy
Piraeus (Athens), Greece · Santorini (Thira), Greece · … · Civitavecchia (Rome), Italy8 ports
Piraeus (Athens), Greece · Santorini (Thira), Greece · Kusadasi (Ephesus), Turkey · Istanbul, Turkey · Rhodes, Greece · Messina, Sicily, Italy · Valletta, Malta · Civitavecchia (Rome), Italy
★ Bucket-list The Acropolis & Parthenon, Guided Skip-the-LineSemi-Private Caldera Catamaran with Hot Springs &…Ephesus + the Terrace Houses with a licensed archa…Hagia Sophia + the upper gallery mosaics with a li… +4 more
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from $2,711
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 26 – Oct 3, 2026 from Marseille, France
Marseille, France · Genoa, Italy · … · Marseille, France7 ports
Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount… +2 more
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from $1,079
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 27 – Oct 4, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di Barumini +2 more
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from $1,118
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 27 – Oct 4, 2026 from Genoa, Italy
Genoa, Italy · Naples, Italy · … · Genoa, Italy7 ports
Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,385
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Celebrity · Celebrity EclipseOne-way
Mediterranean 11 nights Sep 28 – Oct 9, 2026 from Ravenna, Italy to Piraeus (Athens), Greece
Ravenna, Italy · Split, Croatia · … · Piraeus (Athens), Greece9 ports
Ravenna, Italy · Split, Croatia · Dubrovnik, Croatia · Kotor, Montenegro · Valletta, Malta · Rhodes, Greece · Mykonos, Greece · Santorini (Thira), Greece · Piraeus (Athens), Greece
★ Bucket-list Private Ravenna UNESCO Mosaics Walk with a Local E…Diocletian's PalaceWalk Dubrovnik's Ancient City WallsClimb the City Walls to San Giovanni Fortress +5 more
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from $2,587
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 28 – Oct 5, 2026 from Marseille, France
Marseille, France · Livorno (Florence/Pisa), Italy · … · Marseille, France7 ports
Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman Palace +2 more
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from $1,320
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 28 – Oct 5, 2026 from Naples, Italy
Naples, Italy · Messina, Sicily, Italy · … · Naples, Italy7 ports
Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,027
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Regent · Seven Seas VoyagerOne-way
Mediterranean 12 nights Sep 28 – Oct 10, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Toulon, France · … · Civitavecchia (Rome), Italy8 ports
Barcelona, Spain · Toulon, France · La Spezia (Cinque Terre), Italy · Willis Island · Valletta, Malta · Willis Island · Sorrento, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaMont FaronPrivate Cinque Terre by Minivan & Ferryboat from L…Zodiac Circumnavigation of Willis Island +3 more
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from $17,299
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 29 – Oct 6, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,027
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 29 – Oct 6, 2026 from Messina, Sicily, Italy
Messina, Sicily, Italy · Valletta, Malta · … · Messina, Sicily, Italy7 ports
Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy
★ Bucket-list Taormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,684
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Regent · Seven Seas MarinerOne-way
Mediterranean 13 nights Sep 29 – Oct 12, 2026 from Civitavecchia (Rome), Italy to Piraeus (Athens), Greece
Civitavecchia (Rome), Italy · Naples, Italy · … · Piraeus (Athens), Greece14 ports
Civitavecchia (Rome), Italy · Naples, Italy · Willis Island · La Goulette, Tunisia · Valletta, Malta · Willis Island · Dubrovnik, Croatia · Bari, Italy · Kotor, Montenegro · Corfu, Greece · Katakolon (Olympia), Greece · Santorini (Thira), Greece · Willis Island · Piraeus (Athens), Greece
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistZodiac Circumnavigation of Willis IslandPrivate Full-Day Carthage, Sidi Bou Said & Bardo M… +8 more
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from $14,349
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 30 – Oct 7, 2026 from Cagliari, Sardinia, Italy
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · … · Cagliari, Sardinia, Italy7 ports
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy
★ Bucket-list Su Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,748
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Sep 30 – Oct 7, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dock +2 more
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from $1,872
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Oceania · Oceania SirenaOne-way
Mediterranean 12 nights Sep 30 – Oct 12, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Palamos, Spain · … · Civitavecchia (Rome), Italy13 ports
Barcelona, Spain · Palamos, Spain · Toulon, France · St. Tropez, France · La Spezia (Cinque Terre), Italy · Ajaccio, Corsica, France · Cagliari, Sardinia, Italy · Trapani, Italy · Valletta, Malta · Messina, Sicily, Italy · Sorrento, Italy · Porto Ercole, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaGironaMont FaronPrivate Riva Boat Tour +9 more
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from $3,315
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 1 – Oct 8, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Valletta, Malta · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,146
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 2 – Oct 9, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +2 more
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from $1,476
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 2 – Oct 9, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed Archaeologist +2 more
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from $1,059
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Regent · Seven Seas NavigatorOne-way
Middle East 14 nights Oct 2 – Oct 16, 2026 from Istanbul, Turkey to Civitavecchia (Rome), Italy
Istanbul, Turkey · Willis Island · … · Civitavecchia (Rome), Italy13 ports
Istanbul, Turkey · Willis Island · Izmir, Turkey · Mykonos, Greece · Piraeus (Athens), Greece · Heraklion, Crete, Greece · Willis Island · Alexandria, Egypt · Willis Island · Valletta, Malta · Messina, Sicily, Italy · Salerno, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Hagia Sophia + the upper gallery mosaics with a li…Zodiac Circumnavigation of Willis IslandPrivate Ephesus & House of the Virgin MaryDelos +7 more
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from $45,999
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Costa · Costa DeliziosaRound-trip
Mediterranean 7 nights Oct 3 – Oct 10, 2026 from Trieste, Italy
Trieste, Italy · Bari, Italy · … · Trieste, Italy7 ports
Trieste, Italy · Bari, Italy · Corfu, Greece · Syracuse, Sicily · Valletta, Malta · Split, Croatia · Trieste, Italy
★ Bucket-list Miramare CastleMatera & the Sassi cave city with a licensed Basil…Paleokastritsa Blue Caves & coves by speedboatNeapolis Archaeological Park +2 more
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from $989
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 3 – Oct 10, 2026 from Marseille, France
Marseille, France · Genoa, Italy · … · Marseille, France7 ports
Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount… +2 more
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from $1,080
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 4 – Oct 11, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di Barumini +2 more
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from $1,170
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 4 – Oct 11, 2026 from Genoa, Italy
Genoa, Italy · Naples, Italy · … · Genoa, Italy7 ports
Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,385
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 5 – Oct 12, 2026 from Marseille, France
Marseille, France · Livorno (Florence/Pisa), Italy · … · Marseille, France7 ports
Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman Palace +2 more
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from $1,216
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 5 – Oct 12, 2026 from Naples, Italy
Naples, Italy · Messina, Sicily, Italy · … · Naples, Italy7 ports
Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,098
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 6 – Oct 13, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,788
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 6 – Oct 13, 2026 from Messina, Sicily, Italy
Messina, Sicily, Italy · Valletta, Malta · … · Messina, Sicily, Italy7 ports
Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy
★ Bucket-list Taormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $3,196
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 7 – Oct 14, 2026 from Cagliari, Sardinia, Italy
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · … · Cagliari, Sardinia, Italy7 ports
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy
★ Bucket-list Su Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,246
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 7 – Oct 14, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dock +2 more
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from $855
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Silversea · Silver MuseOne-way
Mediterranean 14 nights Oct 7 – Oct 21, 2026 from Fusina (Venice), Italy to Lisbon, Portugal
Fusina (Venice), Italy · Piran, Slovenia · … · Lisbon, Portugal12 ports
Fusina (Venice), Italy · Piran, Slovenia · Zadar, Croatia · Hvar, Croatia · Dubrovnik, Croatia · Taormina, Sicily, Italy · Valletta, Malta · Trapani, Italy · Cagliari, Sardinia, Italy · Cartagena, Spain · Malaga, Spain · Lisbon, Portugal
★ Bucket-list Private Gondola RidePrivate Piran Walking Tour with Wine & Food TastingKornati National Park & TelašćicaBlue Cave & Vis Island Private Speedboat Day +8 more
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from $12,150
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Holland America · VolendamRound-trip
Mediterranean 45 nights Oct 8 – Nov 22, 2026 from New York, New York
New York, New York · Ponta Delgada, Azores, Portugal · … · New York, New York23 ports
New York, New York · Ponta Delgada, Azores, Portugal · Lisbon, Portugal · Cartagena, Spain · Barcelona, Spain · Villefranche, France · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Naples, Italy · Messina, Sicily, Italy · Kefalonia, Greece · Iraklion (Heraklion), Crete, Greece · Rhodes, Greece · Bodrum, Turkey · Kusadasi (Ephesus), Turkey · Istanbul, Turkey · Piraeus (Athens), Greece · Valletta, Malta · La Goulette, Tunisia · Malaga, Spain · Cadiz (Seville), Spain · Funchal, Madeira, Portugal · New York, New York
★ Bucket-list Manhattan Helicopter TourSete Cidades Twin LakesSintraThe Roman Theatre of Cartagena with the Rafael Mon… +18 more
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from $6,224
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 8 – Oct 15, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Valletta, Malta · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,150
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Silversea · Silver SpiritOne-way
Mediterranean 10 nights Oct 8 – Oct 18, 2026 from Civitavecchia (Rome), Italy to Fusina (Venice), Italy
Civitavecchia (Rome), Italy · Naples, Italy · … · Fusina (Venice), Italy10 ports
Civitavecchia (Rome), Italy · Naples, Italy · Amalfi, Italy · Taormina, Sicily, Italy · Valletta, Malta · Kotor, Montenegro · Split, Croatia · Zadar, Croatia · Rovinj, Croatia · Fusina (Venice), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistPrivate Speedboat TourAncient Theatre of Taormina +6 more
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from $9,550
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Carnival · Carnival FreedomRound-trip
Mediterranean 8 nights Oct 9, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Naples, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $799
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 9 – Oct 16, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +2 more
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from $1,016
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 9 – Oct 16, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed Archaeologist +2 more
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from $966
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Regent · Seven Seas GrandeurOne-way
Mediterranean 11 nights Oct 9 – Oct 20, 2026 from Lisbon, Portugal to Valletta, Malta
Lisbon, Portugal · Portimao, Portugal · … · Valletta, Malta11 ports
Lisbon, Portugal · Portimao, Portugal · Cadiz (Seville), Spain · Malaga, Spain · Almeria, Spain · Willis Island · Cagliari, Sardinia, Italy · La Goulette, Tunisia · Trapani, Italy · Willis Island · Valletta, Malta
★ Bucket-list SintraPrivate Benagil Cave Boat TourReal Alcázar de SevillaGranada & the Alhambra +6 more
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from $12,599
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Celebrity · Celebrity EquinoxRound-trip
Mediterranean 10 nights Oct 10 – Oct 20, 2026 from Barcelona, Spain
Barcelona, Spain · Valletta, Malta · … · Barcelona, Spain8 ports
Barcelona, Spain · Valletta, Malta · Messina, Sicily, Italy · Naples, Italy · Civitavecchia (Rome), Italy · La Spezia (Cinque Terre), Italy · Villefranche, France · Barcelona, Spain
★ Bucket-list Sagrada FamiliaSt John's Co-Cathedral & the Caravaggio masterpiecesTaormina's Ancient Greek Theatre, framed by Mount…Pompeii with a Licensed Archaeologist +3 more
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from $7,577
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 10 – Oct 17, 2026 from Marseille, France
Marseille, France · Genoa, Italy · … · Marseille, France7 ports
Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount… +2 more
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from $987
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Regent · Seven Seas VoyagerOne-way
Mediterranean 7 nights Oct 10 – Oct 17, 2026 from Civitavecchia (Rome), Italy to Fusina (Venice), Italy
Civitavecchia (Rome), Italy · Naples, Italy · … · Fusina (Venice), Italy8 ports
Civitavecchia (Rome), Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Willis Island · Dubrovnik, Croatia · Zadar, Croatia · Fusina (Venice), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpieces +4 more
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from $8,749
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 11 – Oct 18, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di Barumini +2 more
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from $1,281
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 11 – Oct 18, 2026 from Genoa, Italy
Genoa, Italy · Naples, Italy · … · Genoa, Italy7 ports
Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,416
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 12 – Oct 19, 2026 from Marseille, France
Marseille, France · Livorno (Florence/Pisa), Italy · … · Marseille, France7 ports
Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman Palace +2 more
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from $1,119
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 12 – Oct 19, 2026 from Naples, Italy
Naples, Italy · Messina, Sicily, Italy · … · Naples, Italy7 ports
Naples, Italy · Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,125
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Regent · Seven Seas MarinerOne-way
Mediterranean 14 nights Oct 12 – Oct 26, 2026 from Piraeus (Athens), Greece to Barcelona, Spain
Piraeus (Athens), Greece · Mykonos, Greece · … · Barcelona, Spain15 ports
Piraeus (Athens), Greece · Mykonos, Greece · Bozcaada, Turkey · Istanbul, Turkey · Mytilene, Lesbos, Greece · Kusadasi (Ephesus), Turkey · Willis Island · Valletta, Malta · Messina, Sicily, Italy · Sorrento, Italy · Civitavecchia (Rome), Italy · La Spezia (Cinque Terre), Italy · Monte Carlo, Monaco · Willis Island · Barcelona, Spain
★ Bucket-list The Acropolis & Parthenon, Guided Skip-the-LineDelosHagia Sophia + the upper gallery mosaics with a li…Private Castle of Mytilene & Old Town Walking Tour +9 more
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from $11,299
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Viking Ocean · Viking VelaRound-trip
Mediterranean 15 nights Oct 12 – Oct 27, 2026 from Tarragona, Spain
Tarragona, Spain · Marseille, France · … · Tarragona, Spain15 ports
Tarragona, Spain · Marseille, France · Ajaccio, Corsica, France · Civitavecchia (Rome), Italy · Sail the Mediterranean Sea · Valletta, Malta · La Goulette, Tunisia · Sail the Mediterranean Sea · Algiers, Algeria · Sail the Strait of Gibraltar · Casablanca, Morocco · Cadiz (Seville), Spain · Malaga, Spain · Sail the Balearic Sea · Tarragona, Spain
★ Bucket-list Private Roman TarracoCalanques National Park Boat Cruise from the Old P…Sanguinaires Islands & CalanquesVatican, Sistine Chapel & Colosseum in One Day +6 more
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from $14,399
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 13 – Oct 20, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,063
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 13 – Oct 20, 2026 from Messina, Sicily, Italy
Messina, Sicily, Italy · Valletta, Malta · … · Messina, Sicily, Italy7 ports
Messina, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy
★ Bucket-list Taormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,256
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Oceania · Oceania InsigniaOne-way
Mediterranean 10 nights Oct 13 – Oct 23, 2026 from Civitavecchia (Rome), Italy to Venice, Italy
Civitavecchia (Rome), Italy · Sorrento, Italy · … · Venice, Italy11 ports
Civitavecchia (Rome), Italy · Sorrento, Italy · Messina, Sicily, Italy · Valletta, Malta · Crotone · Corfu, Greece · Kotor, Montenegro · Dubrovnik, Croatia · Zadar, Croatia · Koper, Slovenia · Venice, Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii Private Excavation Tour with Archaeologist…Taormina's Ancient Greek Theatre, framed by Mount…St John's Co-Cathedral & the Caravaggio masterpieces +7 more
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from $4,399
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 14 – Oct 21, 2026 from Cagliari, Sardinia, Italy
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · … · Cagliari, Sardinia, Italy7 ports
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy
★ Bucket-list Su Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,772
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MSC Cruises · MSC World EuropaRound-trip
Mediterranean 7 nights Oct 14 – Oct 21, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Genoa, Italy · Naples, Italy · Messina, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dock +2 more
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from $1,465
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Silversea · Silver MuseOne-way
Mediterranean 7 nights Oct 14 – Oct 21, 2026 from Valletta, Malta to Lisbon, Portugal
Valletta, Malta · Trapani, Italy · … · Lisbon, Portugal6 ports
Valletta, Malta · Trapani, Italy · Cagliari, Sardinia, Italy · Cartagena, Spain · Malaga, Spain · Lisbon, Portugal
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesEriceSu Nuraxi di BaruminiThe Roman Theatre of Cartagena with the Rafael Mon… +2 more
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from $5,500
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 15 – Oct 22, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Valletta, Malta · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,338
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