⚓ Cruises

Royal Caribbean Mediterranean cruises

201 itineraries with a bookable sailing ahead, 221 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › Royal Caribbean Mediterranean cruises

Sailing from

Port Canaveral1 Miami1 New Orleans1 Fort Lauderdale (Port Everglades)2 Civitavecchia (Rome)65 Barcelona49 Ravenna35 Piraeus (Athens)31 Southampton10 Lisbon4 Cape Liberty (Bayonne)1 Istanbul1

Page 3 of 6

Ranked by what people search for and where the cruise lines send the most ships.

7-night Mediterranean from Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

5 ports
Round trip
Sails Jun 6, 2027
From $1,503 pp
Contemporary

Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Ephesus Private Ephesus Tour with Expert Local Guide & On-Time Return
Mykonos Delos: a whole UNESCO island that is one open-air ruin

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

5 ports
Round trip
Sails Jun 27, 2027
From $1,555 pp
Contemporary

Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Ephesus Private Ephesus Tour with Expert Local Guide & On-Time Return
Mykonos Delos: a whole UNESCO island that is one open-air ruin

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

5 ports
Round trip
Sails Jul 4, 2027
From $1,468 pp
Contemporary

Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Ephesus Private Ephesus Tour with Expert Local Guide & On-Time Return
Mykonos Delos: a whole UNESCO island that is one open-air ruin

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

5 ports
Round trip
Sails Jul 11, 2027
From $1,570 pp
Contemporary

Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Ephesus Private Ephesus Tour with Expert Local Guide & On-Time Return
Mykonos Delos: a whole UNESCO island that is one open-air ruin

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

5 ports
Round trip
Sails Jul 18, 2027
From $1,471 pp
Contemporary

Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Ephesus Private Ephesus Tour with Expert Local Guide & On-Time Return
Mykonos Delos: a whole UNESCO island that is one open-air ruin

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

5 ports
Round trip
Sails Aug 8, 2027
From $1,400 pp
Contemporary

Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Ephesus Private Ephesus Tour with Expert Local Guide & On-Time Return
Mykonos Delos: a whole UNESCO island that is one open-air ruin

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

5 ports
Round trip
Sails Sep 5, 2027
From $1,128 pp
Contemporary

Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Ephesus Private Ephesus Tour with Expert Local Guide & On-Time Return
Mykonos Delos: a whole UNESCO island that is one open-air ruin

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

5 ports
Round trip
Sails Sep 19, 2027
From $1,030 pp
Contemporary

Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Ephesus Private Ephesus Tour with Expert Local Guide & On-Time Return
Mykonos Delos: a whole UNESCO island that is one open-air ruin

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

5 ports
Round trip
Sails Sep 26, 2027
From $1,025 pp
Contemporary

Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Ephesus Private Ephesus Tour with Expert Local Guide & On-Time Return
Mykonos Delos: a whole UNESCO island that is one open-air ruin

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

5 ports
Round trip
Sails Oct 3, 2027
From $954 pp
Contemporary

Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Ephesus Private Ephesus Tour with Expert Local Guide & On-Time Return
Mykonos Delos: a whole UNESCO island that is one open-air ruin

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

5 ports
Round trip
Sails Oct 10, 2027
From $1,056 pp
Contemporary

Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Ephesus Private Ephesus Tour with Expert Local Guide & On-Time Return
Mykonos Delos: a whole UNESCO island that is one open-air ruin

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

5 ports
Round trip
Sails Oct 17, 2027
From $986 pp
Contemporary

Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Ephesus Private Ephesus Tour with Expert Local Guide & On-Time Return
Mykonos Delos: a whole UNESCO island that is one open-air ruin

See the whole trip →

7-night Mediterranean from Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

5 ports
Round trip
Sails Oct 24, 2027
From $940 pp
Contemporary

Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Ephesus Private Ephesus Tour with Expert Local Guide & On-Time Return
Mykonos Delos: a whole UNESCO island that is one open-air ruin

See the whole trip →

7-night Civitavecchia (Rome) to Piraeus (Athens)

Royal Caribbean · Brilliance of the Seas

7 ports
One way
Sails Sep 28, 2026
From $1,243 pp
Contemporary

Naples Pompeii with a Licensed Archaeologist
Messina Taormina's Ancient Greek Theatre, framed by Mount Etna
Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch

See the whole trip →

7-night Civitavecchia (Rome) to Piraeus (Athens)

Royal Caribbean · Explorer of the Seas

7 ports
One way
Sails Jul 5, 2027
From $1,328 pp
Contemporary

Naples Pompeii with a Licensed Archaeologist
Messina Taormina's Ancient Greek Theatre, framed by Mount Etna
Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch

See the whole trip →

7-night Civitavecchia (Rome) to Piraeus (Athens)

Royal Caribbean · Explorer of the Seas

7 ports
One way
Sails Sep 27, 2027
From $869 pp
Contemporary

Naples Pompeii with a Licensed Archaeologist
Messina Taormina's Ancient Greek Theatre, framed by Mount Etna
Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch

See the whole trip →

14-night Fort Lauderdale (Port Everglades) to Barcelona

Royal Caribbean · Legend Of The Seas

5 ports
Repositioning
Sails Apr 25, 2027
From $1,699 pp
Contemporary

Cadiz (Seville) Real Alcázar de Sevilla: Private Expert-Led Palace Access
Malaga Granada & the Alhambra: Spain's Most Famous Monument
Alicante Castillo de Santa Bárbara: Private Guided Summit & Old Town

See the whole trip →

14-night Cape Liberty (Bayonne) to Civitavecchia (Rome)

Royal Caribbean · Odyssey of the Seas

7 ports
Repositioning
Sails Apr 25, 2027
From $1,326 pp
Contemporary

Ponta Delgada Sete Cidades Twin Lakes: Private Full-Island Jeep Safari
Malaga Granada & the Alhambra: Spain's Most Famous Monument
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach

See the whole trip →

14-night Civitavecchia (Rome) to Cape Liberty (Bayonne)

Royal Caribbean · Odyssey of the Seas

7 ports
Repositioning
Sails Oct 25, 2026
From $2,361 pp
Contemporary

La Spezia (Cinque Terre) Private Cinque Terre by Minivan & Ferryboat from La Spezia
Barcelona Sagrada Familia: Gaudi's Basilica + Tower Climb
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach

See the whole trip →

7-night Civitavecchia (Rome) to Ravenna

Royal Caribbean · Brilliance of the Seas

7 ports
One way
Sails Oct 19, 2026
From $7,694 pp
Contemporary

Naples Pompeii with a Licensed Archaeologist
Messina Taormina's Ancient Greek Theatre, framed by Mount Etna
Valletta St John's Co-Cathedral & the Caravaggio masterpieces

See the whole trip →

7-night Barcelona to Ravenna

Royal Caribbean · Explorer of the Seas

7 ports
One way
Sails Jun 21, 2027
From $984 pp
Contemporary

Toulon Mont Faron: Cable Car, Big Cats & WWII Panorama
Ajaccio Sanguinaires Islands & Calanques: Private Speedboat Odyssey
Civitavecchia (Rome) Vatican, Sistine Chapel & Colosseum in One Day (skip-the-line, private)

See the whole trip →

7-night Barcelona to Ravenna

Royal Caribbean · Explorer of the Seas

7 ports
One way
Sails Aug 2, 2027
From $930 pp
Contemporary

Toulon Mont Faron: Cable Car, Big Cats & WWII Panorama
Villefranche Private Riviera Half-Day: Eze, Monaco & Monte Carlo
Civitavecchia (Rome) Vatican, Sistine Chapel & Colosseum in One Day (skip-the-line, private)

See the whole trip →

11-night Barcelona to Piraeus (Athens)

Royal Caribbean · Rhapsody of the Seas

10 ports
One way
Sails May 3, 2027
From $2,002 pp
Contemporary

La Spezia (Cinque Terre) Private Cinque Terre by Minivan & Ferryboat from La Spezia
Civitavecchia (Rome) Vatican, Sistine Chapel & Colosseum in One Day (skip-the-line, private)
Amalfi Private Speedboat Tour: Amalfi Coast Sea Caves & Positano

See the whole trip →

15-night Fort Lauderdale (Port Everglades) to Barcelona

Royal Caribbean · Brilliance of the Seas

8 ports
Repositioning
Sails Apr 23, 2027
From $1,081 pp
Contemporary

Nassau Swim With the Wild Exuma Pigs (Full-Day Powerboat to a Private Island)
Tangier Tangier Kasbah, Medina & American Legation Private Tour
Cadiz (Seville) Real Alcázar de Sevilla: Private Expert-Led Palace Access

See the whole trip →

14-night Port Canaveral to Barcelona

Royal Caribbean · Explorer of the Seas

7 ports
Repositioning
Sails Apr 26, 2027
From $820 pp
Contemporary

Funchal Pico do Arieiro to Pico Ruivo: Madeira's Rooftop Ridge Walk
Cadiz (Seville) Real Alcázar de Sevilla: Private Expert-Led Palace Access
Malaga Granada & the Alhambra: Spain's Most Famous Monument

See the whole trip →

10-night Barcelona to Ravenna

Royal Caribbean · Mariner of the Seas

8 ports
One way
Sails Jun 5, 2027
From $1,363 pp
Contemporary

Palermo Cappella Palatina & the Norman Palace — Palermo's gold-mosaic masterpiece
Santorini (Thira) Semi-Private Caldera Catamaran with Hot Springs & BBQ Lunch
Piraeus (Athens) The Acropolis & Parthenon, Guided Skip-the-Line

See the whole trip →

7-night Ravenna to Civitavecchia (Rome)

Royal Caribbean · Brilliance of the Seas

7 ports
One way
Sails Oct 30, 2027
From $1,083 pp
Contemporary

Split Diocletian's Palace: Private Guided Tour + Underground Cellars
Kotor Climb the City Walls to San Giovanni Fortress
Dubrovnik Walk Dubrovnik's Ancient City Walls: The Full Circuit

See the whole trip →

13-night Barcelona to Port Canaveral

Royal Caribbean · Explorer of the Seas

6 ports
Repositioning
Sails Oct 31, 2026
From $1,029 pp
Contemporary

Palma de Mallorca La Seu Cathedral + Rooftop Terraces Climb
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Ponta Delgada Sete Cidades Twin Lakes: Private Full-Island Jeep Safari

See the whole trip →

8-night Barcelona to Civitavecchia (Rome)

Royal Caribbean · Mariner of the Seas

8 ports
One way
Sails Aug 20, 2027
From $959 pp
Contemporary

Palma de Mallorca La Seu Cathedral + Rooftop Terraces Climb
Toulon Mont Faron: Cable Car, Big Cats & WWII Panorama
Villefranche Private Riviera Half-Day: Eze, Monaco & Monte Carlo

See the whole trip →

14-night Miami to Barcelona

Royal Caribbean · Rhapsody of the Seas

7 ports
Repositioning
Sails Apr 19, 2027
From $808 pp
Contemporary

Bimini Swim with Wild Dolphins at Honeymoon Harbour
Gibraltar Upper Rock Nature Reserve: Private Taxi Grand Tour
Malaga Granada & the Alhambra: Spain's Most Famous Monument

See the whole trip →

7-night Ravenna to Barcelona

Royal Caribbean · Mariner of the Seas

7 ports
One way
Sails Jul 9, 2027
From $1,009 pp
Contemporary

Dubrovnik Walk Dubrovnik's Ancient City Walls: The Full Circuit
Corfu Paleokastritsa Blue Caves & coves by speedboat — the 'Capri of Greece'
Argostoli Myrtos Beach & Melissani Cave: Full-Day Private Island Tour

See the whole trip →

7-night Ravenna to Barcelona

Royal Caribbean · Mariner of the Seas

7 ports
One way
Sails Aug 13, 2027
From $885 pp
Contemporary

Zadar Kornati National Park & Telašćica: Private Luxury Boat Day
Dubrovnik Walk Dubrovnik's Ancient City Walls: The Full Circuit
Corfu Paleokastritsa Blue Caves & coves by speedboat — the 'Capri of Greece'

See the whole trip →

7-night Barcelona to Ravenna

Royal Caribbean · Explorer of the Seas

7 ports
One way
Sails May 10, 2027
From $858 pp
Contemporary

Toulon Mont Faron: Cable Car, Big Cats & WWII Panorama
Ajaccio Sanguinaires Islands & Calanques: Private Speedboat Odyssey
Civitavecchia (Rome) Vatican, Sistine Chapel & Colosseum in One Day (skip-the-line, private)

See the whole trip →

7-night Barcelona to Ravenna

Royal Caribbean · Explorer of the Seas

7 ports
One way
Sails Sep 13, 2027
From $705 pp
Contemporary

Toulon Mont Faron: Cable Car, Big Cats & WWII Panorama
Ajaccio Sanguinaires Islands & Calanques: Private Speedboat Odyssey
Civitavecchia (Rome) Vatican, Sistine Chapel & Colosseum in One Day (skip-the-line, private)

See the whole trip →