Bucket-List Cruise Adventures

Cruises from Cape Town, South Africa

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Filtering From Cape Town, South Africa × Clear all
Showing 23 of 23 sailings
Silversea · Silver MuseOne-way
Africa 22 nights Nov 10 – Dec 2, 2026 from Cape Town, South Africa to Mumbai (Bombay), India
Cape Town, South Africa · Port Elizabeth, South Africa · … · Mumbai (Bombay), India10 ports
Cape Town, South Africa · Port Elizabeth, South Africa · East London, South Africa · Durban, South Africa · Pointe des Galets, Reunion Island · Port Louis, Mauritius · Mahe, Seychelles Islands · Cochin, India · Mangalore, India · Mumbai (Bombay), India
★ Bucket-list Table MountainSchotia Private Game ReservePrivate Big 5 Safari at Inkwenkwezi Game ReserveSani Pass 4x4 Ascent +6 more
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from $7,450
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Regent · Seven Seas VoyagerOne-way
Middle East 61 nights Feb 1 – Apr 3, 2027 from Cape Town, South Africa to Barcelona, Spain
Cape Town, South Africa · Port Elizabeth, South Africa · … · Barcelona, Spain28 ports
Cape Town, South Africa · Port Elizabeth, South Africa · Durban, South Africa · Mayotte, Comoros Isles · Nosy Be, Madagascar · Diego Suarez (Antsiranana), Madagascar · Port Louis, Mauritius · Praslin, Seychelles Islands · Male, Maldives · Colombo, Sri Lanka · Cochin, India · Mumbai (Bombay), India · Salalah, Oman · Jeddah, Saudi Arabia · Aqaba, Jordan · Luxor/Karnak (Safaga), Egypt · Haifa, Israel · Piraeus (Athens), Greece · Sorrento, Italy · Civitavecchia (Rome), Italy · La Spezia (Cinque Terre), Italy · Portofino, Italy · Cannes, France · Mahon, Minorca, Spain · Palma de Mallorca, Spain · Ibiza, Spain · Valencia, Spain · Barcelona, Spain
★ Bucket-list Table MountainSchotia Private Game ReserveSani Pass 4x4 AscentMayotte Lagoon +24 more
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from $50,749
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Oceania · Oceania SirenaOne-way
Mediterranean 24 nights Feb 7 – Mar 3, 2027 from Cape Town, South Africa to Lisbon, Portugal
Cape Town, South Africa · Luderitz, Namibia · … · Lisbon, Portugal13 ports
Cape Town, South Africa · Luderitz, Namibia · Walvis Bay, Namibia · Principe Island, Sao Tome and Principe · Lome, Togo · Takoradi, Ghana · Abidjan, Ivory Coast · Banjul, Gambia · Dakar, Senegal · Mindelo, Cape Verde Island · Arrecife, Lanzarote, Canary Islands · Agadir, Morocco · Lisbon, Portugal
★ Bucket-list Table MountainKolmanskop Ghost TownSandwich Harbour 4x4Príncipe Rainforest & Obô Natural Park Private Saf… +9 more
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from $10,199
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Regent · Seven Seas NavigatorOne-way
Australia & South Pacific 28 nights Mar 9 – Apr 6, 2027 from Cape Town, South Africa to Singapore, Singapore
Cape Town, South Africa · Willis Island · … · Singapore, Singapore20 ports
Cape Town, South Africa · Willis Island · Port Elizabeth, South Africa · Willis Island · Maputo, Mozambique · Willis Island · Nosy Be, Madagascar · Willis Island · Dar es Salaam, Tanzania · Willis Island · Mahe, Seychelles Islands · Willis Island · Male, Maldives · Willis Island · Hambantota, Sri Lanka · Willis Island · Phuket, Thailand · Penang, Malaysia · Port Klang (Kuala Lumpur), Malaysia · Singapore, Singapore
★ Bucket-list Table MountainZodiac Circumnavigation of Willis IslandSchotia Private Game ReserveMaputo Special Reserve +9 more
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from $21,849
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MSC Cruises · MSC ArmoniaRound-trip
Africa 5 nights Mar 16 – Mar 21, 2027 from Cape Town, South Africa
Cape Town, South Africa · Walvis Bay, Namibia · Cape Town, South Africa
★ Bucket-list Table MountainSandwich Harbour 4x4
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from $717
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MSC Cruises · MSC ArmoniaRound-trip
Africa 5 nights Mar 21 – Mar 26, 2027 from Cape Town, South Africa
Cape Town, South Africa · Walvis Bay, Namibia · Cape Town, South Africa
★ Bucket-list Table MountainSandwich Harbour 4x4
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from $766
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Holland America · VolendamRepositioning
Mediterranean 35 nights Mar 22 – Apr 26, 2027 from Cape Town, South Africa to Rotterdam, The Netherlands
Cape Town, South Africa · Luderitz, Namibia · … · Rotterdam, The Netherlands18 ports
Cape Town, South Africa · Luderitz, Namibia · Walvis Bay, Namibia · Jamestown, St. Helena · Banjul, Gambia · Dakar, Senegal · Praia, Cape Verde · Mindelo, Cape Verde Island · Santa Cruz de Tenerife, Canary Islands · Las Palmas, Gran Canaria, Canary Islands · Lanzarote, Canary Islands, Spain · Casablanca, Morocco · Lisbon, Portugal · Leixoes (Oporto), Portugal · Bilbao, Spain · Bordeaux, France · Cherbourg, France · Rotterdam, The Netherlands
★ Bucket-list Table MountainKolmanskop Ghost TownSandwich Harbour 4x4Aaron's Adventure Tours +13 more
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from $7,999
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Costa · Costa DeliziosaOne-way
Mediterranean 18 nights Mar 24 – Apr 11, 2027 from Cape Town, South Africa to Marseille, France
Cape Town, South Africa · Walvis Bay, Namibia · … · Marseille, France6 ports
Cape Town, South Africa · Walvis Bay, Namibia · Mindelo, Cape Verde Island · Las Palmas, Gran Canaria, Canary Islands · Barcelona, Spain · Marseille, France
★ Bucket-list Table MountainSandwich Harbour 4x4Private Full-Day São Vicente Island Discovery TourRoque Nublo & Tejeda +2 more
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from $1,939
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MSC Cruises · MSC ArmoniaRound-trip
Africa 3 nights Mar 26 – Mar 29, 2027 from Cape Town, South Africa
Cape Town, South Africa · Indiske Ocean · Cape Town, South Africa
★ Bucket-list Table Mountain
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from $461
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MSC Cruises · MSC ArmoniaOne-way
Middle East 29 nights Mar 29 – Apr 27, 2027 from Cape Town, South Africa to Venice, Italy
Cape Town, South Africa · Durban, South Africa · … · Venice, Italy14 ports
Cape Town, South Africa · Durban, South Africa · La Possession, Reunion · Port Louis, Mauritius · Diego Suarez (Antsiranana), Madagascar · Fort Dauphin, Madagascar · Port Victoria, Seychelles · Aqaba, Jordan · Sharm-el-Sheikh, Egypt · Suez Canal, Egypt · Rhodes, Greece · Heraklion, Crete, Greece · Split, Croatia · Venice, Italy
★ Bucket-list Table MountainSani Pass 4x4 AscentPrivate Helicopter Grand TourÎle aux Cerfs +10 more
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from $2,549
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Cunard · Queen VictoriaOne-way
Northern Europe 20 nights Apr 10 – Apr 30, 2027 from Cape Town, South Africa to Southampton, England
Cape Town, South Africa · Walvis Bay, Namibia · … · Southampton, England6 ports
Cape Town, South Africa · Walvis Bay, Namibia · Dakar, Senegal · Santa Cruz de Tenerife, Canary Islands · Funchal, Madeira, Portugal · Southampton, England
★ Bucket-list Table MountainSandwich Harbour 4x4Gorée IslandTeide National Park +2 more
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from $3,119
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Silversea · Silver DawnOne-way
Africa 19 nights Apr 11 – Apr 30, 2027 from Cape Town, South Africa to Dakar, Senegal
Cape Town · Cape Town, South Africa · … · Dakar, Senegal10 ports
Cape Town · Cape Town, South Africa · Luderitz, Namibia · Walvis Bay, Namibia · Luanda, Angola · Tema (Accra), Ghana · Takoradi, Ghana · Abidjan, Ivory Coast · Banjul, Gambia · Dakar, Senegal
★ Bucket-list Table MountainKolmanskop Ghost TownSandwich Harbour 4x4Kissama +5 more
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from $18,100
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Regent · Seven Seas NavigatorOne-way
Mediterranean 20 nights Nov 20 – Dec 10, 2027 from Cape Town, South Africa to Lisbon, Portugal
Cape Town, South Africa · Willis Island · … · Lisbon, Portugal17 ports
Cape Town, South Africa · Willis Island · Walvis Bay, Namibia · Willis Island · Principe Island, Sao Tome and Principe · Willis Island · Lome, Togo · Takoradi, Ghana · Abidjan, Ivory Coast · Willis Island · Dakar, Senegal · Willis Island · Mindelo, Cape Verde Island · Willis Island · Santa Cruz de Tenerife, Canary Islands · Willis Island · Lisbon, Portugal
★ Bucket-list Table MountainZodiac Circumnavigation of Willis IslandSandwich Harbour 4x4Príncipe Rainforest & Obô Natural Park Private Saf… +7 more
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from $13,399
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MSC Cruises · MSC SinfoniaRound-trip
Africa 5 nights Jan 10 – Jan 15, 2028 from Cape Town, South Africa
Cape Town, South Africa · Walvis Bay, Namibia · Cape Town, South Africa
★ Bucket-list Table MountainSandwich Harbour 4x4
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from $674
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MSC Cruises · MSC SinfoniaRound-trip
Africa 5 nights Jan 23 – Jan 28, 2028 from Cape Town, South Africa
Cape Town, South Africa · Walvis Bay, Namibia · Cape Town, South Africa
★ Bucket-list Table MountainSandwich Harbour 4x4
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from $674
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MSC Cruises · MSC SinfoniaRound-trip
Africa 3 nights Jan 28 – Jan 31, 2028 from Cape Town, South Africa
Cape Town, South Africa · Indian Ocean · Cape Town, South Africa
★ Bucket-list Table Mountain
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from $388
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Viking Ocean · Viking NeptuneRepositioning
Asia 36 nights Feb 2 – Mar 9, 2028 from Cape Town, South Africa to Tokyo, Japan
Cape Town, South Africa · Sail the Indian Ocean · … · Tokyo, Japan24 ports
Cape Town, South Africa · Sail the Indian Ocean · Port Elizabeth, South Africa · Sail the Indian Ocean · Durban, South Africa · Sail the Indian Ocean · Zanzibar, Tanzania · Mombasa, Kenya · Sail the Indian Ocean · Victoria, Seychelles · Sail the Indian Ocean · Sail the Laccadive Sea · Colombo, Sri Lanka · Sail the Bay of Bengal · Langkawi, Malaysia · Scenic Sailing: Strait of Malacca · Singapore, Singapore · Sail the South China Sea · Manila, Philippines · Sail the South China Sea · Okinawa (Naha), Japan · Sail the East China Sea · Sail the Pacific Ocean · Tokyo, Japan
★ Bucket-list Table MountainSchotia Private Game ReserveSani Pass 4x4 AscentSafari Blue +8 more
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from $12,999
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Cunard · Queen ElizabethOne-way
Asia 20 nights Feb 5 – Feb 25, 2028 from Cape Town, South Africa to Singapore, Singapore
Cape Town, South Africa · Port Elizabeth, South Africa · … · Singapore, Singapore8 ports
Cape Town, South Africa · Port Elizabeth, South Africa · Durban, South Africa · Reunion, Reunion · Port Louis, Mauritius · Penang, Malaysia · Port Klang (Kuala Lumpur), Malaysia · Singapore, Singapore
★ Bucket-list Table MountainSchotia Private Game ReserveSani Pass 4x4 AscentPiton de la Fournaise +4 more
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from $2,969
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Princess · Coral PrincessRepositioning
Panama Canal 65 nights Mar 9 – May 13, 2028 from Cape Town, South Africa to Los Angeles, California
Cape Town, South Africa · Walvis Bay, Namibia · … · Los Angeles, California33 ports
Cape Town, South Africa · Walvis Bay, Namibia · Mindelo, Cape Verde Island · Santa Cruz de Tenerife, Canary Islands · Gibraltar, British Territory · Syracuse, Sicily · Corfu, Greece · Dubrovnik, Croatia · Split, Croatia · Kotor, Montenegro · Piraeus (Athens), Greece · Kusadasi (Ephesus), Turkey · Chania, Greece · Salerno, Italy · Civitavecchia (Rome), Italy · Ajaccio, Corsica, France · Santa Margherita, Italy · Cannes, France · Barcelona, Spain · Malaga, Spain · Seville, Spain · Tangier, Morocco · Casablanca, Morocco · Funchal, Madeira, Portugal · Azores Islands, Portugal · Fort Lauderdale (Port Everglades), Florida · Cartagena, Colombia · Panama Canal, Panama · Acajulta, El Salvador · Puerto Chiapas, Mexico · Huatulco, Mexico · Puerto Vallarta, Mexico · Los Angeles, California
★ Bucket-list Table MountainSandwich Harbour 4x4Private Full-Day São Vicente Island Discovery TourTeide National Park +29 more
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from $10,655
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Seabourn · Seabourn QuestOne-way
Northern Europe 38 nights Mar 29 – May 6, 2028 from Cape Town, South Africa to Southampton, England
Cape Town, South Africa · Luderitz, Namibia · … · Southampton, England22 ports
Cape Town, South Africa · Luderitz, Namibia · Walvis Bay, Namibia · Luanda, Angola · Principe Island, Sao Tome and Principe · Cotonou, Benin · Tema (Accra), Ghana · Takoradi, Ghana · Dakar, Senegal · Mindelo, Cape Verde Island · Las Palmas, Gran Canaria, Canary Islands · Arrecife, Lanzarote, Canary Islands · Casablanca, Morocco · Tangier, Morocco · Cadiz (Seville), Spain · Lisbon, Portugal · Leixoes (Oporto), Portugal · La Coruna, Spain · St. Malo, France · Cherbourg, France · Rouen, France · Southampton, England
★ Bucket-list Table MountainKolmanskop Ghost TownSandwich Harbour 4x4Kissama +18 more
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from $25,754
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Cunard · Queen AnneRepositioning
Northern Europe 17 nights Apr 15 – May 2, 2028 from Cape Town, South Africa to Southampton, England
Cape Town, South Africa · St. Vincent (Sao Vicente), Cape Verde Islands · Gran Canaria, Canary Islands · Funchal, Madeira, Portugal · Southampton, England
★ Bucket-list Table MountainSanto Antão Full-DayRed Canyon & Hidden GemsPico do Arieiro to Pico Ruivo +1 more
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from $2,439
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Regent · Seven Seas MarinerOne-way
Mediterranean 21 nights Apr 28 – May 19, 2028 from Cape Town, South Africa to Lisbon, Portugal
Cape Town, South Africa · Willis Island · … · Lisbon, Portugal18 ports
Cape Town, South Africa · Willis Island · Walvis Bay, Namibia · Willis Island · Luanda, Angola · Willis Island · Principe Island, Sao Tome and Principe · Willis Island · Abidjan, Ivory Coast · Willis Island · Banjul, Gambia · Willis Island · Mindelo, Cape Verde Island · Willis Island · Santa Cruz de Tenerife, Canary Islands · Funchal, Madeira, Portugal · Willis Island · Lisbon, Portugal
★ Bucket-list Table MountainZodiac Circumnavigation of Willis IslandSandwich Harbour 4x4Kissama +7 more
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from $15,699
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Azamara · Azamara OnwardOne-way
Mediterranean 24 nights May 9 – Jun 2, 2028 from Cape Town, South Africa to Barcelona, Spain
Cape Town, South Africa · Luderitz, Namibia · … · Barcelona, Spain12 ports
Cape Town, South Africa · Luderitz, Namibia · Walvis Bay, Namibia · Jamestown, St. Helena · Praia, Cape Verde · Las Palmas, Gran Canaria, Canary Islands · Arrecife, Lanzarote, Canary Islands · Agadir, Morocco · Casablanca, Morocco · Gibraltar, British Territory · Malaga, Spain · Barcelona, Spain
★ Bucket-list Table MountainKolmanskop Ghost TownSandwich Harbour 4x4Aaron's Adventure Tours +7 more
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from $9,105
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Itineraries from the Cruisebound catalog + our enrichment; schedules cross-checked against official port authorities. Booking via Cruisebound and CruiseDirect — we may earn a commission, at no extra cost to you.

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MSC Cruises Royal Caribbean Carnival Viking River Norwegian AmaWaterways Costa Princess Celebrity Avalon Disney Viking Ocean Holland America Silversea Oceania Virgin Regent Explora Journeys Cunard Azamara Windstar Seabourn Virgin Voyages