Bucket-List Cruise Adventures

Cruises from San Diego, California

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Filtering From San Diego, California × Clear all
Showing 36 of 175 sailings
Disney · Disney MagicRound-trip
Mexico 4 nights Sep 21 – Sep 25, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $942
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Disney · Disney MagicRound-trip
Mexico 3 nights Sep 25 – Sep 28, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $940
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Disney · Disney MagicRound-trip
Mexico 3 nights Sep 28 – Oct 1, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $784
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Disney · Disney MagicRound-trip
Mexico 4 nights Oct 1 – Oct 5, 2026 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
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from $1,137
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Holland America · Nieuw AmsterdamOne-way
Bahamas 16 nights Oct 2 – Oct 18, 2026 from San Diego, California to Fort Lauderdale (Port Everglades), Florida
San Diego, California · Puerto Vallarta, Mexico · … · Fort Lauderdale (Port Everglades), Florida10 ports
San Diego, California · Puerto Vallarta, Mexico · Huatulco, Mexico · Puerto Chiapas, Mexico · Puerto Quetzal, Guatemala · Acajutla, El Salvador · Panama Canal, Panama · Cartagena, Colombia · Half Moon Cay (Little San Salvador Island), Bahamas · Fort Lauderdale (Port Everglades), Florida
★ Bucket-list San Diego ZooHidden Beach at Marietas IslandsCopalitilla Magic WaterfallsPrivate Sumidero Canyon Boat Safari & Chiapa de Co… +6 more
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from $1,529
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 2 nights Oct 2 – Oct 4, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $317
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Disney · Disney WonderRound-trip
Mexico 7 nights Oct 3 – Oct 10, 2026 from San Diego, California
San Diego, California · Puerto Vallarta, Mexico · Cabo San Lucas, Mexico · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooHidden Beach at Marietas IslandsEl Arco & Lover's BeachValle de Guadalupe wine country
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from $1,292
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MSC Cruises · MSC PoesiaRepositioning
Caribbean 14 nights Oct 3 – Oct 17, 2026 from San Diego, California to Miami, Florida
San Diego, California · Cabo San Lucas, Mexico · … · Miami, Florida6 ports
San Diego, California · Cabo San Lucas, Mexico · Puntarenas, Costa Rica · Colon, Panama · Cartagena, Colombia · Miami, Florida
★ Bucket-list San Diego ZooEl Arco & Lover's BeachMonteverde Cloud ForestPanama Canal Full Transit +2 more
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from $1,056
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Oct 4 – Oct 11, 2026 from San Diego, California
San Diego, California · La Paz, Mexico · Cabo San Lucas, Mexico · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooWhale Shark SnorkelEl Arco & Lover's BeachValle de Guadalupe wine country
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from $489
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Disney · Disney MagicRound-trip
Mexico 4 nights Oct 5 – Oct 9, 2026 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
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from $993
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Holland America · EurodamOne-way
Caribbean 16 nights Oct 8 – Oct 24, 2026 from San Diego, California to Fort Lauderdale (Port Everglades), Florida
San Diego, California · Cabo San Lucas, Mexico · … · Fort Lauderdale (Port Everglades), Florida10 ports
San Diego, California · Cabo San Lucas, Mexico · Acapulco, Mexico · Huatulco, Mexico · Puerto Chiapas, Mexico · Puerto Quetzal, Guatemala · Puntarenas, Costa Rica · Panama Canal, Panama · Port of Oranjestad, Aruba, Caribbean · Fort Lauderdale (Port Everglades), Florida
★ Bucket-list San Diego ZooEl Arco & Lover's BeachLa Quebrada Cliff DiversCopalitilla Magic Waterfalls +6 more
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from $1,699
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Holland America · ZaandamRound-trip
Mexico 7 nights Oct 8 – Oct 15, 2026 from San Diego, California
San Diego, California · Cabo San Lucas, Mexico · Pichilingue (La Paz), Mexico · Loreto, Mexico · San Diego, California
★ Bucket-list San Diego ZooEl Arco & Lover's BeachIsla Espíritu SantoCoronado Island
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from $949
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Disney · Disney MagicRound-trip
Mexico 3 nights Oct 9 – Oct 12, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $967
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Disney · Disney WonderRound-trip
Mexico 3 nights Oct 10 – Oct 13, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $886
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 4 nights Oct 11 – Oct 15, 2026 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
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from $304
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Disney · Disney MagicRound-trip
Mexico 4 nights Oct 12 – Oct 16, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $950
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Holland America · ZaandamRound-trip
Australia & South Pacific 35 nights Oct 15 – Nov 19, 2026 from San Diego, California
San Diego, California · Nawiliwili, Kauai · … · San Diego, California18 ports
San Diego, California · Nawiliwili, Kauai · Honolulu, Oahu, Hawaii · Kahului, Maui, Hawaii · Kona, Hawaii · Cross International Dateline · Fanning Island, Kiribati · Crossing The Equator · Rangiroa, Tahiti · Huahine, French Polynesia · Bora Bora, French Polynesia · Raiatea, French Polynesia · Papeete, Tahiti, French Polynesia · Moorea, French Polynesia · Fakarava, Tahiti · Taiohae, Nuku Hiva, Marquesas · Crossing The Equator · San Diego, California
★ Bucket-list San Diego ZooNā Pali Coast Doors-Off Helicopter TourPearl HarborHaleakalā Sunrise +10 more
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from $4,699
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 3 nights Oct 15 – Oct 18, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $276
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Disney · Disney MagicRound-trip
Mexico 3 nights Oct 16 – Oct 19, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $934
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Disney · Disney WonderRound-trip
Mexico 4 nights Oct 18 – Oct 22, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $958
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Oct 18 – Oct 25, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · Cabo San Lucas, Mexico · La Paz, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine countryEl Arco & Lover's BeachWhale Shark Snorkel
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from $527
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Disney · Disney MagicRound-trip
Mexico 5 nights Oct 19 – Oct 24, 2026 from San Diego, California
San Diego, California · Cabo San Lucas, Mexico · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooEl Arco & Lover's BeachValle de Guadalupe wine country
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from $992
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Holland America · KoningsdamRound-trip
Mexico 11 nights Oct 20 – Oct 31, 2026 from San Diego, California
San Diego, California · Manzanillo, Mexico · … · San Diego, California8 ports
San Diego, California · Manzanillo, Mexico · Puerto Vallarta, Mexico · Mazatlan, Mexico · Pichilingue (La Paz), Mexico · Loreto, Mexico · Cabo San Lucas, Mexico · San Diego, California
★ Bucket-list San Diego ZooColonial Colima & ComalaHidden Beach at Marietas IslandsIsla de Venados +3 more
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from $899
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Disney · Disney WonderRound-trip
Mexico 5 nights Oct 22 – Oct 27, 2026 from San Diego, California
San Diego, California · Cabo San Lucas, Mexico · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooEl Arco & Lover's BeachValle de Guadalupe wine country
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from $1,162
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Disney · Disney MagicRound-trip
Mexico 6 nights Oct 24 – Oct 30, 2026 from San Diego, California
San Diego, California · Cabo San Lucas, Mexico · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooEl Arco & Lover's BeachValle de Guadalupe wine country
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from $1,014
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Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Oct 25 – Nov 1, 2026 from San Diego, California
San Diego, California · La Paz, Mexico · Cabo San Lucas, Mexico · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooWhale Shark SnorkelEl Arco & Lover's BeachValle de Guadalupe wine country
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from $469
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Disney · Disney WonderRound-trip
Mexico 6 nights Oct 27 – Nov 2, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · Cabo San Lucas, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine countryEl Arco & Lover's Beach
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from $1,014
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Disney · Disney MagicRound-trip
Mexico 7 nights Oct 30 – Nov 6, 2026 from San Diego, California
San Diego, California · Puerto Vallarta, Mexico · Cabo San Lucas, Mexico · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooHidden Beach at Marietas IslandsEl Arco & Lover's BeachValle de Guadalupe wine country
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from $1,264
Book This Cruise@ Cruisebound
Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Nov 1 – Nov 8, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · Cabo San Lucas, Mexico · Mazatlan, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine countryEl Arco & Lover's BeachIsla de Venados
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from $460
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Disney · Disney WonderRound-trip
Mexico 3 nights Nov 2 – Nov 5, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $778
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Disney · Disney WonderRound-trip
Mexico 4 nights Nov 5 – Nov 9, 2026 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Valle de Guadalupe wine country
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from $977
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Disney · Disney MagicRepositioning
Mediterranean 14 nights Nov 6 – Nov 20, 2026 from San Diego, California to Galveston, Texas
San Diego, California · Cabo San Lucas, Mexico · … · Galveston, Texas7 ports
San Diego, California · Cabo San Lucas, Mexico · Puerto Vallarta, Mexico · Panama City, Panama · Cartagena, Spain · Georgetown, Grand Cayman, Cayman Islands · Galveston, Texas
★ Bucket-list San Diego ZooEl Arco & Lover's BeachHidden Beach at Marietas IslandsPanama Canal Miraflores Locks +3 more
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from $2,967
Book This Cruise@ Cruisebound
Royal Caribbean · Serenade of the SeasRound-trip
Mexico 7 nights Nov 8 – Nov 15, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · Cabo San Lucas, Mexico · Mazatlan, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine countryEl Arco & Lover's BeachIsla de Venados
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from $459
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Disney · Disney WonderRound-trip
Mexico 4 nights Nov 9 – Nov 13, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
View →
from $994
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Disney · Disney WonderRound-trip
Mexico 3 nights Nov 13 – Nov 16, 2026 from San Diego, California
San Diego, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooValle de Guadalupe wine country
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from $943
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Holland America · KoningsdamRound-trip
Mexico 7 nights Nov 14 – Nov 21, 2026 from San Diego, California
San Diego, California · Avalon, Catalina Island, California · San Francisco, California · Ensenada, Mexico · San Diego, California
★ Bucket-list San Diego ZooPrivate Golf Cart Tour of Avalon with Expert Local…Alcatraz IslandValle de Guadalupe wine country
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from $849
Book This Cruise@ Cruisebound
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Itineraries from the Cruisebound catalog + our enrichment; schedules cross-checked against official port authorities. Booking via Cruisebound and CruiseDirect — we may earn a commission, at no extra cost to you.

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MSC Cruises Royal Caribbean Carnival Viking River Costa Norwegian AmaWaterways Princess Celebrity Viking Ocean Avalon Disney Holland America Oceania Virgin Voyages Regent Cunard Seabourn Azamara