Bucket-List Cruise Adventures

Cruises from Santo Domingo, Dominican Republic

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Filtering From Santo Domingo, Dominican Republic × Clear all
Showing 28 of 28 sailings
Costa · Costa FavolosaRound-trip
Caribbean 7 nights Nov 30 – Dec 7, 2026 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Pointe-a-Pitre, Guadeloupe · … · Santo Domingo, Dominican Republic8 ports
Santo Domingo, Dominican Republic · Pointe-a-Pitre, Guadeloupe · Fort-de-France, Martinique · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Antigua, Antigua & Barbuda · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialDeath in Paradise Filming Locations & Botanical Ga…Mount Pelée & Saint-PierreMt. Liamuiga Volcano Crater Hike +2 more
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from $2,399
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Costa · Costa FavolosaRound-trip
Caribbean 7 nights Dec 7 – Dec 14, 2026 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Antigua, Antigua & Barbuda · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga…Mt. Liamuiga Volcano Crater Hike +2 more
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from $1,779
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Costa · Costa FavolosaRound-trip
Caribbean 7 nights Dec 14 – Dec 21, 2026 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Antigua, Antigua & Barbuda · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga…Mt. Liamuiga Volcano Crater Hike +2 more
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from $672
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Costa · Costa FavolosaRound-trip
Caribbean 7 nights Dec 21 – Dec 28, 2026 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Martinique Bay · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Martinique Bay · Fort-de-France, Martinique · Pointe-a-Pitre, Guadeloupe · Philipsburg, St. Maarten · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga…Random Wind 'Paradise Day Sail' +2 more
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from $795
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Costa · Costa FavolosaRound-trip
Caribbean 7 nights Dec 28 – Jan 4, 2027 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Castries, St. Lucia · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Philipsburg, St. Maarten · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga…Cosol Tours +2 more
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from $2,751
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Costa · Costa FavolosaRound-trip
Caribbean 7 nights Jan 4 – Jan 11, 2027 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $706
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Costa · Costa FavolosaRound-trip
Caribbean 7 nights Jan 11 – Jan 18, 2027 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Philipsburg, St. Maarten · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Philipsburg, St. Maarten · Martinique Bay · Fort-de-France, Martinique · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialRandom Wind 'Paradise Day Sail'Mount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $701
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Costa · Costa FavolosaRound-trip
Caribbean 7 nights Jan 18 – Jan 25, 2027 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Philipsburg, St. Maarten · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $625
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Costa · Costa FavolosaRound-trip
Caribbean 7 nights Jan 25 – Feb 1, 2027 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Roseau, Dominica · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Roseau, Dominica · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialBoiling Lake HikeMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $774
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Costa · Costa FavolosaRound-trip
Caribbean 7 nights Feb 1 – Feb 8, 2027 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Martinique Bay · Fort-de-France, Martinique · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Philipsburg, St. Maarten · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $803
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Costa · Costa FavolosaRound-trip
Caribbean 7 nights Feb 8 – Feb 15, 2027 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $672
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Costa · Costa FavolosaRound-trip
Caribbean 7 nights Feb 15 – Feb 22, 2027 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Martinique Bay · Fort-de-France, Martinique · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $672
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Costa · Costa FavolosaRound-trip
Caribbean 7 nights Feb 22 – Mar 1, 2027 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $884
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Costa · Costa FavolosaOne-way
Mediterranean 19 nights Mar 1 – Mar 20, 2027 from Santo Domingo, Dominican Republic to Marseille, France
Santo Domingo, Dominican Republic · Philipsburg, St. Maarten · … · Marseille, France12 ports
Santo Domingo, Dominican Republic · Philipsburg, St. Maarten · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Antigua, Antigua & Barbuda · Santa Cruz de Tenerife, Canary Islands · Tangier, Morocco · Malaga, Spain · Barcelona, Spain · Marseille, France
★ Bucket-list Zona ColonialRandom Wind 'Paradise Day Sail'Mount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +7 more
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from $1,685
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Costa · Costa SerenaRound-trip
Caribbean 7 nights Dec 6 – Dec 13, 2027 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Antigua, Antigua & Barbuda · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga…Mt. Liamuiga Volcano Crater Hike +2 more
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from $1,029
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Costa · Costa SerenaRound-trip
Caribbean 7 nights Dec 13 – Dec 20, 2027 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Antigua, Antigua & Barbuda · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Philipsburg, St. Maarten · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga…Adventure Antigua +2 more
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from $999
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Costa · Costa SerenaRound-trip
Caribbean 7 nights Dec 20 – Dec 27, 2027 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Antigua, Antigua & Barbuda · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga…Mt. Liamuiga Volcano Crater Hike +2 more
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from $1,409
Book This Cruise@ Cruisebound
Costa · Costa SerenaRound-trip
Caribbean 7 nights Dec 27 – Jan 3, 2028 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Philipsburg, St. Maarten · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga…Mt. Liamuiga Volcano Crater Hike +2 more
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from $1,557
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Costa · Costa SerenaRound-trip
Caribbean 7 nights Jan 3 – Jan 10, 2028 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $1,239
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Costa · Costa SerenaRound-trip
Caribbean 7 nights Jan 10 – Jan 17, 2028 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $1,069
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Costa · Costa SerenaRound-trip
Caribbean 7 nights Jan 17 – Jan 24, 2028 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $1,069
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Costa · Costa SerenaRound-trip
Caribbean 7 nights Jan 24 – Jan 31, 2028 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $1,069
Book This Cruise@ Cruisebound
Costa · Costa SerenaRound-trip
Caribbean 7 nights Jan 31 – Feb 7, 2028 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $1,069
Book This Cruise@ Cruisebound
Costa · Costa SerenaRound-trip
Caribbean 7 nights Feb 7 – Feb 14, 2028 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Philipsburg, St. Maarten · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $1,089
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Costa · Costa SerenaRound-trip
Caribbean 7 nights Feb 14 – Feb 21, 2028 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $1,119
Book This Cruise@ Cruisebound
Costa · Costa SerenaRound-trip
Caribbean 7 nights Feb 21 – Feb 28, 2028 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $1,119
Book This Cruise@ Cruisebound
Costa · Costa SerenaRound-trip
Caribbean 7 nights Feb 28 – Mar 6, 2028 from Santo Domingo, Dominican Republic
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Santo Domingo, Dominican Republic9 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Port of Basseterre, St. Kitts, St. Kitts and Nevis · Sea Of Antilles Darkest Spot · Road Town, Tortola, B.V.I. · Santo Domingo, Dominican Republic
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +2 more
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from $1,069
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Costa · Costa SerenaOne-way
Mediterranean 18 nights Mar 6 – Mar 24, 2028 from Santo Domingo, Dominican Republic to Savona (Genoa), Italy
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · … · Savona (Genoa), Italy11 ports
Santo Domingo, Dominican Republic · Antigua, Antigua & Barbuda · Fort-de-France, Martinique · Martinique Bay · Pointe-a-Pitre, Guadeloupe · Philipsburg, St. Maarten · Santa Cruz de Tenerife, Canary Islands · Tangier, Morocco · Barcelona, Spain · Marseille, France · Savona (Genoa), Italy
★ Bucket-list Zona ColonialAdventure AntiguaMount Pelée & Saint-PierreDeath in Paradise Filming Locations & Botanical Ga… +6 more
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from $1,449
Book This Cruise@ Cruisebound

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MSC Cruises Royal Caribbean Carnival Viking River Norwegian AmaWaterways Costa Princess Celebrity Avalon Disney Viking Ocean Holland America Silversea Oceania Virgin Regent Explora Journeys Cunard Azamara Windstar Seabourn Virgin Voyages