⚓ Cruises

Regent Mediterranean cruises from Lisbon

19 itineraries with a bookable sailing ahead, 19 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › Regent Mediterranean cruises from Lisbon

Most popular first

Ranked by what people search for and where the cruise lines send the most ships.

Willis Island

11-night Lisbon to Barcelona

Regent · Seven Seas Mariner

10 ports
One way
Sails May 19, 2028
From $9,499 pp
Luxury

Willis Island Zodiac Circumnavigation of Willis Island: Seabirds & Reef
Cadiz (Seville) Real Alcázar de Sevilla: Private Expert-Led Palace Access
Almeria Private Alhambra Palace & Generalife Gardens from Almeria

See the whole trip →

Portimao

7-night Lisbon to Barcelona

Regent · Seven Seas Grandeur

7 ports
One way
Sails May 8, 2027
From $7,999 pp
Luxury

Portimao Private Benagil Cave Boat Tour – Exclusive Algarve Access
Cadiz (Seville) Real Alcázar de Sevilla: Private Expert-Led Palace Access
Tangier Tangier Kasbah, Medina & American Legation Private Tour

See the whole trip →

Willis Island

14-night Lisbon to Civitavecchia (Rome)

Regent · Seven Seas Splendor

14 ports
One way
Sails Oct 17, 2027
From $9,699 pp
Luxury

Willis Island Zodiac Circumnavigation of Willis Island: Seabirds & Reef
Cadiz (Seville) Real Alcázar de Sevilla: Private Expert-Led Palace Access
Tangier Tangier Kasbah, Medina & American Legation Private Tour

See the whole trip →

Cadiz (Seville)

9-night Lisbon to Barcelona

Regent · Seven Seas Explorer

7 ports
One way
Sails Aug 16, 2028
From $9,199 pp
Luxury

Cadiz (Seville) Real Alcázar de Sevilla: Private Expert-Led Palace Access
Tangier Tangier Kasbah, Medina & American Legation Private Tour
Almeria Private Alhambra Palace & Generalife Gardens from Almeria

See the whole trip →

Portimao

9-night Lisbon to Barcelona

Regent · Seven Seas Prestige

10 ports
One way
Sails Jun 8, 2027
From $12,749 pp
Luxury

Portimao Private Benagil Cave Boat Tour – Exclusive Algarve Access
Cadiz (Seville) Real Alcázar de Sevilla: Private Expert-Led Palace Access
Tangier Tangier Kasbah, Medina & American Legation Private Tour

See the whole trip →

Portimao

7-night Lisbon to Barcelona

Regent · Seven Seas Grandeur

8 ports
One way
Sails May 6, 2028
From $5,499 pp
Luxury

Portimao Private Benagil Cave Boat Tour – Exclusive Algarve Access
Cadiz (Seville) Real Alcázar de Sevilla: Private Expert-Led Palace Access
Almeria Private Alhambra Palace & Generalife Gardens from Almeria

See the whole trip →

Portimao

7-night Lisbon to Barcelona

Regent · Seven Seas Splendor

7 ports
One way
Sails Nov 7, 2027
From $5,399 pp
Luxury

Portimao Private Benagil Cave Boat Tour – Exclusive Algarve Access
Algeciras Tangier Private Day Tour with Ferry from Algeciras
Casablanca Private Guided Tour of Casablanca with Hassan II Mosque Entry

See the whole trip →

Willis Island

10-night Lisbon to Barcelona

Regent · Seven Seas Voyager

10 ports
One way
Sails Nov 3, 2027
From $8,399 pp
Luxury

Willis Island Zodiac Circumnavigation of Willis Island: Seabirds & Reef
Funchal Pico do Arieiro to Pico Ruivo: Madeira's Rooftop Ridge Walk
Santa Cruz de Tenerife Teide National Park: Summit Cable Car & Volcanic Moonscape

See the whole trip →

Santa Cruz de Tenerife

19-night Mediterranean from Lisbon

Regent · Seven Seas Explorer

15 ports
Round trip
Sails Jul 28, 2028
From $18,499 pp
Luxury

Santa Cruz de Tenerife Teide National Park: Summit Cable Car & Volcanic Moonscape
Santa Cruz de La Palma Tajogaite Volcano: Licensed Expert Trek into La Palma's Last Eruption
Tangier Tangier Kasbah, Medina & American Legation Private Tour

See the whole trip →

Portimao

11-night Lisbon to Valletta

Regent · Seven Seas Grandeur

10 ports
One way
Sails Oct 9, 2026
From $12,599 pp
Luxury

Portimao Private Benagil Cave Boat Tour – Exclusive Algarve Access
Cadiz (Seville) Real Alcázar de Sevilla: Private Expert-Led Palace Access
Malaga Granada & the Alhambra: Spain's Most Famous Monument

See the whole trip →

Willis Island

9-night Mediterranean from Lisbon

Regent · Seven Seas Splendor

8 ports
Round trip
Sails Oct 8, 2027
From $8,499 pp
Luxury

Willis Island Zodiac Circumnavigation of Willis Island: Seabirds & Reef
Funchal Pico do Arieiro to Pico Ruivo: Madeira's Rooftop Ridge Walk
Santa Cruz de Tenerife Teide National Park: Summit Cable Car & Volcanic Moonscape

See the whole trip →

Willis Island

11-night Mediterranean from Lisbon

Regent · Seven Seas Prestige

10 ports
Round trip
Sails Apr 9, 2028
From $12,099 pp
Luxury

Willis Island Zodiac Circumnavigation of Willis Island: Seabirds & Reef
Funchal Pico do Arieiro to Pico Ruivo: Madeira's Rooftop Ridge Walk
Santa Cruz de La Palma Tajogaite Volcano: Licensed Expert Trek into La Palma's Last Eruption

See the whole trip →

Porto

10-night Lisbon to Southampton

Regent · Seven Seas Grandeur

9 ports
One way
Sails Aug 17, 2027
From $9,599 pp
Luxury

Porto Private Douro Valley Wine Tour: Two Regions, Lunch & River Cruise
La Coruna Santiago de Compostela: Private Full-Day Pilgrimage City Tour
Bilbao Guggenheim Bilbao: Private Guided Tour + Puppy & Titan Access

See the whole trip →

Willis Island

10-night Mediterranean from Lisbon

Regent · Seven Seas Grandeur

5 ports
Round trip
Sails Apr 28, 2027
From $9,199 pp
Luxury

Willis Island Zodiac Circumnavigation of Willis Island: Seabirds & Reef
Santander Altamira Caves & Santillana del Mar: Spain's Prehistoric Masterpiece
Bordeaux Saint-Émilion Private Wine Estate Tour & Grand Cru Tasting

See the whole trip →

Porto

12-night Lisbon to Southampton

Regent · Seven Seas Voyager

11 ports
One way
Sails May 12, 2028
From $9,899 pp
Luxury

Porto Private Douro Valley Wine Tour: Two Regions, Lunch & River Cruise
Vigo Cíes Islands: Sailboat Excursion with Private Skipper
La Coruna Santiago de Compostela: Private Full-Day Pilgrimage City Tour

See the whole trip →

Porto

9-night Lisbon to Southampton

Regent · Seven Seas Prestige

10 ports
One way
Sails Apr 20, 2028
From $10,899 pp
Luxury

Porto Private Douro Valley Wine Tour: Two Regions, Lunch & River Cruise
La Coruna Santiago de Compostela: Private Full-Day Pilgrimage City Tour
Bilbao Guggenheim Bilbao: Private Guided Tour + Puppy & Titan Access

See the whole trip →

Porto

14-night Lisbon to Southampton

Regent · Seven Seas Mariner

12 ports
One way
Sails Jun 9, 2028
From $13,299 pp
Luxury

Porto Private Douro Valley Wine Tour: Two Regions, Lunch & River Cruise
Vigo Cíes Islands: Sailboat Excursion with Private Skipper
La Coruna Santiago de Compostela: Private Full-Day Pilgrimage City Tour

See the whole trip →

Porto

12-night Lisbon to Le Havre (Paris)

Regent · Seven Seas Mariner

10 ports
One way
Sails May 15, 2027
From $11,099 pp
Luxury

Porto Private Douro Valley Wine Tour: Two Regions, Lunch & River Cruise
Willis Island Zodiac Circumnavigation of Willis Island: Seabirds & Reef
La Coruna Santiago de Compostela: Private Full-Day Pilgrimage City Tour

See the whole trip →

Willis Island

25-night Lisbon to Cape Town

Regent · Seven Seas Navigator

14 ports
One way
Sails Feb 12, 2027
From $43,999 pp
Luxury

Willis Island Zodiac Circumnavigation of Willis Island: Seabirds & Reef
Funchal Pico do Arieiro to Pico Ruivo: Madeira's Rooftop Ridge Walk
Las Palmas Roque Nublo & Tejeda: Gran Canaria's Sacred Heart by 4×4

See the whole trip →

Prefer a calendar? →The ports themselves →