⚓ Cruises

Panama Canal cruises

114 itineraries with a bookable sailing ahead, 160 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › Panama Canal cruises

Sailing from

Galveston3 New York2 Tampa2 Miami28 Los Angeles6 Fort Lauderdale (Port Everglades)22 San Juan1 Vancouver2 Colon18 Cartagena9 San Diego4 Panama City4 San Antonio4 Puerto Caldera3

Cruise line

Carnival6 Royal Caribbean28 Norwegian16 MSC Cruises11 Princess17 Disney2 Celebrity2 Viking Ocean7 Oceania3 Holland America6 Silversea2 Virgin3 Windstar3 Regent2 Azamara3 Cunard2 Costa1

Page 2 of 3

Ranked by what people search for and where the cruise lines send the most ships.

11-night Panama Canal from Miami

MSC Cruises · MSC Poesia

7 ports
Round trip
Sails Jan 23, 2028
From $1,113 pp
Contemporary

Montego Bay Martha Brae River Bamboo Rafting — Private Pole
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

See the whole trip →

12-night Panama Canal from Fort Lauderdale (Port Everglades)

Princess · Caribbean Princess

7 ports
Round trip
Sails Jan 13, 2028
From $984 pp
Premium

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

See the whole trip →

11-night Panama Canal from Miami

Norwegian · Norwegian Sun

8 ports
Round trip
Sails Nov 18, 2026
From $959 pp
Contemporary

Great Stirrup Cay Silver Cove Private Villa: Exclusive Island Retreat
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Panama Canal/Gatun Lake Private Panama Canal & Gatun Lake Boat Tour with Monkey Island

See the whole trip →

11-night Panama Canal from Miami

Norwegian · Norwegian Gem

8 ports
Round trip
Sails Nov 30, 2027
From $1,519 pp
Contemporary

Great Stirrup Cay Silver Cove Private Villa: Exclusive Island Retreat
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Panama Canal/Gatun Lake Private Panama Canal & Gatun Lake Boat Tour with Monkey Island

See the whole trip →

10-night Panama Canal from Miami

Norwegian · Norwegian Gem

7 ports
Round trip
Sails Jan 2, 2028
From $1,539 pp
Contemporary

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Panama Canal/Gatun Lake Private Panama Canal & Gatun Lake Boat Tour with Monkey Island
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

See the whole trip →

21-night Panama Canal from Miami

MSC Cruises · MSC Poesia

11 ports
Round trip
Sails Mar 5, 2028
From $2,321 pp
Contemporary

Ocho Rios Blue Hole: Private Cliff-Jump & Hidden Waterfall Swim
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

See the whole trip →

22-night Panama Canal from Miami

MSC Cruises · MSC Poesia

8 ports
Round trip
Sails Dec 23, 2026
From $3,058 pp
Contemporary

Ocho Rios Blue Hole: Private Cliff-Jump & Hidden Waterfall Swim
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

See the whole trip →

12-night Panama Canal from Miami

Norwegian · Norwegian Sun

9 ports
Round trip
Sails Nov 6, 2026
From $1,279 pp
Contemporary

Great Stirrup Cay Silver Cove Private Villa: Exclusive Island Retreat
Cabo Rojo Bahía de las Águilas: Private All-Inclusive Beach Day
Willemstad Private Full-Day Curaçao Island Tour with Local Expert

See the whole trip →

21-night Panama Canal from Miami

MSC Cruises · MSC Poesia

11 ports
Round trip
Sails Nov 11, 2027
From $2,141 pp
Contemporary

Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Cabo Rojo Bahía de las Águilas: Private All-Inclusive Beach Day

See the whole trip →

21-night Panama Canal from Miami

MSC Cruises · MSC Poesia

11 ports
Round trip
Sails Feb 3, 2028
From $2,211 pp
Contemporary

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park
Cabo Rojo Bahía de las Águilas: Private All-Inclusive Beach Day

See the whole trip →

12-night Panama Canal from Miami

Norwegian · Norwegian Sun

9 ports
Round trip
Sails Dec 21, 2026
From $2,319 pp
Contemporary

Great Stirrup Cay Silver Cove Private Villa: Exclusive Island Retreat
Cabo Rojo Bahía de las Águilas: Private All-Inclusive Beach Day
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ

See the whole trip →

10-night Panama Canal from Miami

Norwegian · Norwegian Gem

7 ports
Round trip
Sails Nov 9, 2027
From $1,439 pp
Contemporary

Great Stirrup Cay Silver Cove Private Villa: Exclusive Island Retreat
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Panama Canal/Gatun Lake Private Panama Canal & Gatun Lake Boat Tour with Monkey Island

See the whole trip →

21-night Panama Canal from Miami

MSC Cruises · MSC Poesia

11 ports
Round trip
Sails Mar 18, 2027
From $2,821 pp
Contemporary

Willemstad Private Full-Day Curaçao Island Tour with Local Expert
Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ

See the whole trip →

21-night Panama Canal from Miami

MSC Cruises · MSC Poesia

11 ports
Round trip
Sails Oct 21, 2027
From $2,181 pp
Contemporary

Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Willemstad Private Full-Day Curaçao Island Tour with Local Expert

See the whole trip →

21-night Panama Canal from Miami

MSC Cruises · MSC Poesia

11 ports
Round trip
Sails Dec 2, 2027
From $2,751 pp
Contemporary

Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Willemstad Private Full-Day Curaçao Island Tour with Local Expert

See the whole trip →

12-night Panama Canal from Fort Lauderdale (Port Everglades)

Princess · Caribbean Princess

6 ports
Round trip
Sails Nov 23, 2026
From $974 pp
Premium

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Panama Canal Panama Canal Full Transit: Pacific to Atlantic by Boat

See the whole trip →

15-night Miami to Los Angeles

Norwegian · Norwegian Joy

9 ports
One way
Sails Apr 17, 2028
From $1,999 pp
Contemporary

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day
Panama Canal Panama Canal Full Transit: Pacific to Atlantic by Boat

See the whole trip →

23-night Vancouver to Port Canaveral

Princess · Star Princess

9 ports
Repositioning
Sails Oct 3, 2027
From $2,598 pp
Premium

Seattle Space Needle & Chihuly Garden of Glass: Seattle's Twin Icons
San Francisco Alcatraz Island: Early-Access Cellhouse Audio Tour
Los Angeles Warner Bros. Studio Tour Hollywood: The Ultimate Experience

See the whole trip →

10-night Panama Canal from Colon

Royal Caribbean · Grandeur of the Seas

6 ports
Round trip
Sails Nov 14, 2026
From $1,472 pp
Contemporary

Kralendijk Klein Bonaire: Bioluminescence Snorkel at the Marine Park
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Willemstad Private Full-Day Curaçao Island Tour with Local Expert

See the whole trip →

15-night Miami to Los Angeles

Norwegian · Norwegian Encore

9 ports
One way
Sails Jan 24, 2028
From $2,139 pp
Contemporary

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day
Panama Canal Panama Canal Full Transit: Pacific to Atlantic by Boat

See the whole trip →

12-night Panama Canal from Fort Lauderdale (Port Everglades)

Princess · Caribbean Princess

6 ports
Round trip
Sails Nov 11, 2026
From $949 pp
Premium

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

See the whole trip →

12-night Panama Canal from Fort Lauderdale (Port Everglades)

Princess · Caribbean Princess

6 ports
Round trip
Sails Dec 29, 2026
From $1,194 pp
Premium

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Panama Canal Panama Canal Full Transit: Pacific to Atlantic by Boat

See the whole trip →

12-night Panama Canal from Fort Lauderdale (Port Everglades)

Princess · Caribbean Princess

6 ports
Round trip
Sails Feb 3, 2027
From $1,049 pp
Premium

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

See the whole trip →

12-night Panama Canal from Fort Lauderdale (Port Everglades)

Princess · Caribbean Princess

6 ports
Round trip
Sails Feb 15, 2027
From $1,124 pp
Premium

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Panama Canal Panama Canal Full Transit: Pacific to Atlantic by Boat

See the whole trip →

16-night Los Angeles to Fort Lauderdale (Port Everglades)

Princess · Star Princess

6 ports
Repositioning
Sails Oct 4, 2026
From $8,129 pp
Premium

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Mazatlan Isla de Venados: Snorkeling, Kayaking & Wild Dolphins
Fuerte Amador Panama Canal Partial Transit: Miraflores to Pedro Miguel Locks

See the whole trip →

16-night Fort Lauderdale (Port Everglades) to Los Angeles

Princess · Star Princess

6 ports
Repositioning
Sails Apr 3, 2027
From $1,654 pp
Premium

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Panama Canal Panama Canal Full Transit: Pacific to Atlantic by Boat
Fuerte Amador Panama Canal Partial Transit: Miraflores to Pedro Miguel Locks

See the whole trip →

16-night San Diego to Miami

Norwegian · Norwegian Star

10 ports
One way
Sails Feb 13, 2027
From $1,939 pp
Contemporary

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Acapulco La Quebrada Cliff Divers: VIP Sunset Dinner & Show
Puerto Quetzal Private Antigua Colonial City & Jade Factory Full-Day Tour

See the whole trip →

12-night Panama Canal from Fort Lauderdale (Port Everglades)

Princess · Caribbean Princess

7 ports
Round trip
Sails Dec 2, 2027
From $999 pp
Premium

Amber Cove 27 Charcos of Damajagua: Full Waterfall Canyoneering Adventure
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach

See the whole trip →

17-night Los Angeles to Miami

Norwegian · Norwegian Joy

11 ports
One way
Sails Sep 30, 2027
From $2,319 pp
Contemporary

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Acapulco La Quebrada Cliff Divers: VIP Sunset Dinner & Show
Puerto Quetzal Private Antigua Colonial City & Jade Factory Full-Day Tour

See the whole trip →

12-night Panama Canal from Fort Lauderdale (Port Everglades)

Princess · Caribbean Princess

7 ports
Round trip
Sails Mar 28, 2027
From $944 pp
Premium

Georgetown Stingray City Sandbar: Private Luxury Catamaran Charter
Ocho Rios Blue Hole: Private Cliff-Jump & Hidden Waterfall Swim
Puerto Limon Veragua Rainforest Park: Aerial Tram & Nocturnal Tour

See the whole trip →

11-night Panama Canal from Fort Lauderdale (Port Everglades)

Celebrity · Celebrity Ascent

7 ports
Round trip
Sails Mar 27, 2028
From $2,398 pp
Premium

Puerto Plata The full 27 jumps at the Damajagua Waterfalls (27 Charcos) with certified canyon guides
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Willemstad Private Full-Day Curaçao Island Tour with Local Expert

See the whole trip →

115-night Panama Canal from Los Angeles

Princess · Coral Princess

49 ports
Round trip
Sails Jan 18, 2028
From $18,737 pp
Premium

Kauai Doors-Off Helicopter Tour: All of Kauai from the Sky
Honolulu Pearl Harbor: USS Arizona Memorial & VIP Guided Tour
Apia To Sua Ocean Trench, Waterfalls & Piula Cave Pool – Full Day

See the whole trip →

14-night San Diego to Galveston

Disney · Disney Magic

7 ports
Repositioning
Sails Nov 6, 2026
From $2,477 pp
Premium

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel
Panama City Panama Canal Miraflores Locks: Private VIP Access & Expert Guide

See the whole trip →

11-night Panama Canal from Fort Lauderdale (Port Everglades)

Celebrity · Celebrity Ascent

7 ports
Round trip
Sails Nov 22, 2027
From $1,907 pp
Premium

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Willemstad Private Full-Day Curaçao Island Tour with Local Expert
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

See the whole trip →

19-night Fort Lauderdale (Port Everglades) to Vancouver

Princess · Coral Princess

10 ports
One way
Sails Apr 28, 2028
From $2,519 pp
Premium

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Panama Canal Panama Canal Full Transit: Pacific to Atlantic by Boat
Acajulta Tazumal Mayan Ruins: Private Expert-Led Archaeological Tour

See the whole trip →

14-night San Diego to Galveston

Disney · Disney Magic

6 ports
One way
Sails Nov 4, 2027
From $2,701 pp
Premium

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel
Fuerte Amador Panama Canal Partial Transit: Miraflores to Pedro Miguel Locks

See the whole trip →

22-night New York to Seattle

Norwegian · Norwegian Bliss

13 ports
One way
Sails Apr 9, 2027
From $2,559 pp
Contemporary

Puerto Plata The full 27 jumps at the Damajagua Waterfalls (27 Charcos) with certified canyon guides
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

See the whole trip →