⚓ Cruises

Panama Canal cruises

114 itineraries with a bookable sailing ahead, 160 sailings, most popular first. Each card: how long, how many ports, when, from what price — and the bucket-list thing to do at every stop.

All cruises › Panama Canal cruises

Sailing from

Galveston3 New York2 Tampa2 Miami28 Los Angeles6 Fort Lauderdale (Port Everglades)22 San Juan1 Vancouver2 Colon18 Cartagena9 San Diego4 Panama City4 San Antonio4 Puerto Caldera3

Cruise line

Carnival6 Royal Caribbean28 Norwegian16 MSC Cruises11 Princess17 Disney2 Celebrity2 Viking Ocean7 Oceania3 Holland America6 Silversea2 Virgin3 Windstar3 Regent2 Azamara3 Cunard2 Costa1

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Ranked by what people search for and where the cruise lines send the most ships.

14-night Panama Canal from Fort Lauderdale (Port Everglades)

Viking Ocean · Viking Mars

7 ports
Round trip
Sails Jan 26, 2028
From $6,499 pp
Luxury

Montego Bay Martha Brae River Bamboo Rafting — Private Pole
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day
Puerto Limon Veragua Rainforest Park: Aerial Tram & Nocturnal Tour

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14-night Panama Canal from Fort Lauderdale (Port Everglades)

Viking Ocean · Viking Mars

7 ports
Round trip
Sails Feb 9, 2028
From $6,499 pp
Luxury

Montego Bay Martha Brae River Bamboo Rafting — Private Pole
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day
Puerto Limon Veragua Rainforest Park: Aerial Tram & Nocturnal Tour

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19-night New York to San Francisco

Norwegian · Norwegian Bliss

10 ports
One way
Sails Apr 14, 2028
From $2,429 pp
Contemporary

Puerto Plata The full 27 jumps at the Damajagua Waterfalls (27 Charcos) with certified canyon guides
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

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10-night Fort Lauderdale (Port Everglades) to Panama City

Viking Ocean · Viking Mars

7 ports
One way
Sails Nov 3, 2026
From $4,799 pp
Luxury

Cozumel El Cielo + Palancar + Columbia 3-Stop Snorkel
Belize City Great Blue Hole Flightseeing & Lighthouse Reef Snorkel
Roatan Hold a Sloth at Daniel Johnson's Monkey & Sloth Hangout

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23-night Vancouver to New York

Princess · Coral Princess

11 ports
One way
Sails Sep 22, 2027
From $2,749 pp
Premium

San Diego San Diego Zoo: Wildlife Showcase at the World's Greatest Zoo
Los Angeles Warner Bros. Studio Tour Hollywood: The Ultimate Experience
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel

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10-night Fort Lauderdale (Port Everglades) to Panama City

Viking Ocean · Viking Mars

7 ports
One way
Sails Jan 6, 2028
From $4,699 pp
Luxury

Merida Chichén Itzá: Private Guided Access + Cenote Swim
Cozumel El Cielo + Palancar + Columbia 3-Stop Snorkel
Belize City Great Blue Hole Flightseeing & Lighthouse Reef Snorkel

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14-night West Palm Beach (Port of Palm Beach) to Fort Lauderdale (Port Everglades)

Viking Ocean · Viking Mars

8 ports
One way
Sails Dec 27, 2026
From $6,699 pp
Luxury

Montego Bay Martha Brae River Bamboo Rafting — Private Pole
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day

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10-night Panama City to West Palm Beach (Port of Palm Beach)

Viking Ocean · Viking Mars

7 ports
One way
Sails Dec 17, 2026
From $3,199 pp
Luxury

Colon Panama Canal Full Transit: Locks, History & Pacific in One Day
Puerto Limon Veragua Rainforest Park: Aerial Tram & Nocturnal Tour
Roatan Hold a Sloth at Daniel Johnson's Monkey & Sloth Hangout

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65-night Fort Lauderdale (Port Everglades) to Cape Town

Princess · Coral Princess

25 ports
One way
Sails Jan 3, 2028
From $11,315 pp
Premium

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Panama Canal Panama Canal Full Transit: Pacific to Atlantic by Boat
Acajulta Tazumal Mayan Ruins: Private Expert-Led Archaeological Tour

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10-night Panama City to Miami

Oceania · Oceania Marina

9 ports
One way
Sails Jan 15, 2027
From $5,099 pp
Luxury

Kiel Canal Private Expert Walking Tour of Kiel: History, Secrets & Sea
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Santa Marta Ciudad Perdida (Lost City) Express Trek — Private Guided

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10-night Panama City to Miami

Oceania · Oceania Marina

9 ports
One way
Sails Mar 15, 2027
From $3,510 pp
Luxury

Kiel Canal Private Expert Walking Tour of Kiel: History, Secrets & Sea
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Santa Marta Ciudad Perdida (Lost City) Express Trek — Private Guided

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21-night Fort Lauderdale (Port Everglades) to Vancouver

Holland America · Oosterdam

11 ports
Repositioning
Sails Apr 7, 2028
From $3,434 pp
Premium

Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Panama Canal Panama Canal Full Transit: Pacific to Atlantic by Boat
Puntarenas Monteverde Cloud Forest: Private Guided Reserve Walk & Hanging Bridges

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Half Moon Cay (Little San Salvador Island)

21-night Panama Canal from Fort Lauderdale (Port Everglades)

Holland America · Oosterdam

11 ports
Round trip
Sails Feb 13, 2028
From $3,654 pp
Premium

Half Moon Cay (Little San Salvador Island) Horseback Riding by Land & Sea (Pegasus Ranch)
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach

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21-night Panama Canal from Fort Lauderdale (Port Everglades)

Holland America · Oosterdam

11 ports
Round trip
Sails Mar 5, 2028
From $3,554 pp
Premium

Half Moon Cay (Little San Salvador Island) Horseback Riding by Land & Sea (Pegasus Ranch)
Port of Oranjestad Aruba: Snorkel with Turtles at WW2 Shipwreck & Sunset BBQ
Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach

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14-night Panama Canal from Miami

Regent · Seven Seas Grandeur

12 ports
Round trip
Sails Dec 22, 2027
From $10,699 pp
Luxury

Key West Dry Tortugas National Park: Fort Jefferson Full-Day Ferry
Willis Island Zodiac Circumnavigation of Willis Island: Seabirds & Reef
Cozumel El Cielo + Palancar + Columbia 3-Stop Snorkel

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14-night Miami to Lima

Oceania · Oceania Sirena

11 ports
One way
Sails Jan 5, 2028
From $5,549 pp
Luxury

Georgetown Stingray City Sandbar: Private Luxury Catamaran Charter
Ocho Rios Blue Hole: Private Cliff-Jump & Hidden Waterfall Swim
Santa Marta Ciudad Perdida (Lost City) Express Trek — Private Guided

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15-night Miami to Los Angeles

Virgin · Brilliant Lady

7 ports
Repositioning
Sails Feb 21, 2028
From $2,064 pp
Premium

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Colon Panama Canal Full Transit: Locks, History & Pacific in One Day
Puntarenas Monteverde Cloud Forest: Private Guided Reserve Walk & Hanging Bridges

See the whole trip →

18-night Miami to Los Angeles

Silversea · Silver Dawn

8 ports
One way
Sails Dec 21, 2026
From $14,050 pp
Luxury

Cartagena The Roman Theatre of Cartagena with the Rafael Moneo museum approach
Panama Canal Panama Canal Full Transit: Pacific to Atlantic by Boat
Puntarenas Monteverde Cloud Forest: Private Guided Reserve Walk & Hanging Bridges

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18-night Valparaiso (Santiago) to Miami

Silversea · Silver Nova

8 ports
One way
Sails Mar 5, 2027
From $13,550 pp
Luxury

Arica Lauca National Park & Chungará Lake Full-Day Private Tour
Callao (Lima) Palomino Islands: Swim with Sea Lions in the Pacific
Guayaquil (Quito) Quito Old Town & Mitad del Mundo: Private Full-Day

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16-night Los Angeles to Miami

Virgin · Brilliant Lady

7 ports
Repositioning
Sails Oct 29, 2026
From $9,503 pp
Premium

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Puerto Quetzal Private Antigua Colonial City & Jade Factory Full-Day Tour
Puntarenas Monteverde Cloud Forest: Private Guided Reserve Walk & Hanging Bridges

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16-night Los Angeles to Miami

Virgin · Brilliant Lady

7 ports
Repositioning
Sails Nov 27, 2027
From $1,854 pp
Premium

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Puerto Quetzal Private Antigua Colonial City & Jade Factory Full-Day Tour
Puntarenas Monteverde Cloud Forest: Private Guided Reserve Walk & Hanging Bridges

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15-night San Diego to Fort Lauderdale (Port Everglades)

Holland America · Zaandam

9 ports
One way
Sails Dec 19, 2026
From $1,799 pp
Premium

Cabo San Lucas El Arco & Lover's Beach: Private Yacht at Land's End
Puerto Vallarta Hidden Beach at Marietas Islands: Secret Cove Swim & Snorkel
Huatulco Copalitilla Magic Waterfalls: Private Expert-Led Jungle Trek

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16-night Lima to Miami

Regent · Seven Seas Mariner

13 ports
One way
Sails Mar 10, 2027
From $13,399 pp
Luxury

Salaverry (Trujillo) Chan Chan: Private Guided Tour of the World's Largest Adobe City
Willis Island Zodiac Circumnavigation of Willis Island: Seabirds & Reef
Guayaquil (Quito) Quito Old Town & Mitad del Mundo: Private Full-Day

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16-night San Antonio to Fort Lauderdale (Port Everglades)

Holland America · Oosterdam

10 ports
One way
Sails Mar 24, 2027
From $2,299 pp
Premium

Coquimbo (La Serena) Elqui Valley: Pisco Distillery, Vineyards & Stargazing
General San Martin Ballestas Islands: Private Wildlife Boat Expedition
Callao (Lima) Palomino Islands: Swim with Sea Lions in the Pacific

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17-night San Antonio to Fort Lauderdale (Port Everglades)

Holland America · Nieuw Amsterdam

10 ports
One way
Sails Mar 21, 2028
From $2,894 pp
Premium

Coquimbo (La Serena) Elqui Valley: Pisco Distillery, Vineyards & Stargazing
General San Martin Ballestas Islands: Private Wildlife Boat Expedition
Callao (Lima) Palomino Islands: Swim with Sea Lions in the Pacific

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42-night Miami to Buenos Aires

Azamara · Azamara Quest

22 ports
One way
Sails Jan 5, 2028
From $17,999 pp
Luxury

Cozumel El Cielo + Palancar + Columbia 3-Stop Snorkel
Belize City Great Blue Hole Flightseeing & Lighthouse Reef Snorkel
Roatan Hold a Sloth at Daniel Johnson's Monkey & Sloth Hangout

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19-night San Antonio to Miami

Azamara · Azamara Journey

12 ports
Repositioning
Sails Mar 10, 2027
From $5,847 pp
Luxury

Coquimbo (La Serena) Elqui Valley: Pisco Distillery, Vineyards & Stargazing
Iquique Humberstone & Santa Laura: Private UNESCO Desert Ghost Town Tour
Arica Lauca National Park & Chungará Lake Full-Day Private Tour

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90-night Panama Canal from Hamburg

Cunard · Queen Anne

31 ports
Round trip
Sails Jan 5, 2027
From $12,499 pp
Premium

Rotterdam All-Inclusive Private Windmill Tour to Kinderdijk from Rotterdam
Zeebrugge (Bruges) Private Bruges Full-Day Shore Excursion with Canal Cruise
Southampton Stand Inside Stonehenge & See the Original 1215 Magna Carta at Salisbury

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