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Filtering Regent ×MSC Cruises ×From Lisbon, Portugal × Clear all
Showing 36 of 46 sailings
MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Jun 27 – Jul 7, 2026 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,258
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Jul 7 – Jul 17, 2026 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,262
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Jul 17 – Jul 27, 2026 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,462
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Regent · Seven Seas VoyagerOne-way
Mediterranean 14 nights Jul 20 – Aug 3, 2026 from Lisbon, Portugal to Southampton, England
Lisbon, Portugal · Willis Island · … · Southampton, England10 ports
Lisbon, Portugal · Willis Island · Bordeaux, France · Willis Island · Le Havre (Paris), France · Willis Island · Zeebrugge (Bruges), Belgium · Ijmuiden, Netherlands · Willis Island · Southampton, England
★ Bucket-list SintraZodiac Circumnavigation of Willis IslandSaint-Émilion Private Wine Estate Tour & Grand Cru…Private Paris Highlights & Seine River Cruise from… +3 more
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from $10,625
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Jul 27 – Aug 6, 2026 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,077
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Aug 6 – Aug 16, 2026 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,531
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Aug 16 – Aug 26, 2026 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,737
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Regent · Seven Seas SplendorOne-way
Australia & South Pacific 14 nights Aug 23 – Sep 6, 2026 from Lisbon, Portugal to New York, New York
Lisbon, Portugal · Willis Island · … · New York, New York11 ports
Lisbon, Portugal · Willis Island · Ponta Delgada, Azores, Portugal · Willis Island · St. Johns, Newfoundland · Saint-Pierre, France · Sydney, Nova Scotia · Halifax, Nova Scotia · Boston, Massachusetts · Newport, Rhode Island · New York, New York
★ Bucket-list SintraZodiac Circumnavigation of Willis IslandSete Cidades Twin LakesCape St. Mary's Ecological Reserve +6 more
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from $17,699
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Aug 26 – Sep 5, 2026 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,717
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Sep 5 – Sep 15, 2026 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,447
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Sep 15 – Sep 25, 2026 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,607
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MSC Cruises · MSC OperaRound-trip
Mediterranean 10 nights Sep 25 – Oct 5, 2026 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,421
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Regent · Seven Seas GrandeurOne-way
Mediterranean 11 nights Oct 9 – Oct 20, 2026 from Lisbon, Portugal to Valletta, Malta
Lisbon, Portugal · Portimao, Portugal · … · Valletta, Malta11 ports
Lisbon, Portugal · Portimao, Portugal · Cadiz (Seville), Spain · Malaga, Spain · Almeria, Spain · Willis Island · Cagliari, Sardinia, Italy · La Goulette, Tunisia · Trapani, Italy · Willis Island · Valletta, Malta
★ Bucket-list SintraPrivate Benagil Cave Boat TourReal Alcázar de SevillaGranada & the Alhambra +6 more
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from $12,599
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Regent · Seven Seas NavigatorOne-way
Caribbean 14 nights Nov 23 – Dec 7, 2026 from Lisbon, Portugal to Barcelona, Spain
Lisbon, Portugal · Willis Island · … · Barcelona, Spain14 ports
Lisbon, Portugal · Willis Island · Las Palmas, Gran Canaria, Canary Islands · Funchal, Madeira, Portugal · Santa Cruz de La Palma, Spain · Arrecife, Lanzarote, Canary Islands · Santa Cruz de Tenerife, Canary Islands · Willis Island · Casablanca, Morocco · Cadiz (Seville), Spain · Malaga, Spain · Cartagena, Colombia · Palma de Mallorca, Spain · Barcelona, Spain
★ Bucket-list SintraZodiac Circumnavigation of Willis IslandRoque Nublo & TejedaPico do Arieiro to Pico Ruivo +9 more
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from $8,649
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Regent · Seven Seas NavigatorOne-way
Mediterranean 25 nights Feb 12 – Mar 9, 2027 from Lisbon, Portugal to Cape Town, South Africa
Lisbon, Portugal · Willis Island · … · Cape Town, South Africa20 ports
Lisbon, Portugal · Willis Island · Funchal, Madeira, Portugal · Las Palmas, Gran Canaria, Canary Islands · Santa Cruz de Tenerife, Canary Islands · Willis Island · Mindelo, Cape Verde Island · Willis Island · Dakar, Senegal · Banjul, Gambia · Willis Island · Abidjan, Ivory Coast · Takoradi, Ghana · Lome, Togo · Willis Island · Principe Island, Sao Tome and Principe · Willis Island · Walvis Bay, Namibia · Willis Island · Cape Town, South Africa
★ Bucket-list SintraZodiac Circumnavigation of Willis IslandPico do Arieiro to Pico RuivoRoque Nublo & Tejeda +10 more
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from $30,199
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Regent · Seven Seas GrandeurRound-trip
Mediterranean 10 nights Apr 28 – May 8, 2027 from Lisbon, Portugal
Lisbon, Portugal · Willis Island · … · Lisbon, Portugal7 ports
Lisbon, Portugal · Willis Island · Santander, Spain · Bordeaux, France · Bilbao, Spain · Willis Island · Lisbon, Portugal
★ Bucket-list SintraZodiac Circumnavigation of Willis IslandAltamira Caves & Santillana del MarSaint-Émilion Private Wine Estate Tour & Grand Cru… +1 more
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from $8,649
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Regent · Seven Seas VoyagerOne-way
Northern Europe 11 nights Apr 29 – May 10, 2027 from Lisbon, Portugal to Southampton, England
Lisbon, Portugal · Porto (Oporto), Portugal · … · Southampton, England11 ports
Lisbon, Portugal · Porto (Oporto), Portugal · La Coruna, Spain · Bilbao, Spain · Willis Island · Bordeaux, France · Willis Island · Brest, France · St Helier, Isle of Jersey · Honfleur, France · Southampton, England
★ Bucket-list SintraPrivate Douro Valley Wine TourSantiago de CompostelaGuggenheim Bilbao +6 more
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from $9,499
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Regent · Seven Seas GrandeurOne-way
Mediterranean 17 nights May 8 – May 25, 2027 from Lisbon, Portugal to Civitavecchia (Rome), Italy
Lisbon, Portugal · Portimao, Portugal · … · Civitavecchia (Rome), Italy18 ports
Lisbon, Portugal · Portimao, Portugal · Cadiz (Seville), Spain · Tangier, Morocco · Malaga, Spain · Willis Island · Palma de Mallorca, Spain · Barcelona, Spain · Palamos, Spain · St. Tropez, France · Monte Carlo, Monaco · La Spezia (Cinque Terre), Italy · Willis Island · Trapani, Italy · Reggio Calabria · Olbia, Italy · Sorrento, Italy · Civitavecchia (Rome), Italy
★ Bucket-list SintraPrivate Benagil Cave Boat TourReal Alcázar de SevillaTangier Kasbah, Medina & American Legation Private… +13 more
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from $18,049
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Regent · Seven Seas MarinerOne-way
Mediterranean 12 nights May 15 – May 27, 2027 from Lisbon, Portugal to Le Havre (Paris), France
Lisbon, Portugal · Porto (Oporto), Portugal · … · Le Havre (Paris), France12 ports
Lisbon, Portugal · Porto (Oporto), Portugal · Willis Island · La Coruna, Spain · Gijon, Spain · Bilbao, Spain · Willis Island · Bordeaux, France · La Rochelle, France · Willis Island · St Helier, Isle of Jersey · Le Havre (Paris), France
★ Bucket-list SintraPrivate Douro Valley Wine TourZodiac Circumnavigation of Willis IslandSantiago de Compostela +6 more
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from $12,199
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Jun 2 – Jun 12, 2027 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,631
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Regent · Seven Seas PrestigeOne-way
Mediterranean 9 nights Jun 8 – Jun 17, 2027 from Lisbon, Portugal to Barcelona, Spain
Lisbon, Portugal · Portimao, Portugal · … · Barcelona, Spain10 ports
Lisbon, Portugal · Portimao, Portugal · Cadiz (Seville), Spain · Tangier, Morocco · Malaga, Spain · Willis Island · Alicante, Spain · Ibiza, Spain · Palma de Mallorca, Spain · Barcelona, Spain
★ Bucket-list SintraPrivate Benagil Cave Boat TourReal Alcázar de SevillaTangier Kasbah, Medina & American Legation Private… +6 more
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from $10,149
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Jun 12 – Jun 22, 2027 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Portimao, Portugal · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,691
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Jun 22 – Jul 2, 2027 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Portimao, Portugal · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,771
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Jul 2 – Jul 12, 2027 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,771
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Jul 12 – Jul 22, 2027 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,831
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Jul 22 – Aug 1, 2027 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,901
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Aug 1 – Aug 11, 2027 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Portimao, Portugal · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,931
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Aug 11 – Aug 21, 2027 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $2,081
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Regent · Seven Seas MarinerOne-way
Caribbean 22 nights Aug 11 – Sep 2, 2027 from Lisbon, Portugal to Civitavecchia (Rome), Italy
Lisbon, Portugal · Portimao, Portugal · … · Civitavecchia (Rome), Italy23 ports
Lisbon, Portugal · Portimao, Portugal · Cadiz (Seville), Spain · Tangier, Morocco · Malaga, Spain · Willis Island · Cartagena, Colombia · Alicante, Spain · Ibiza, Spain · Palma de Mallorca, Spain · Willis Island · Barcelona, Spain · Palamos, Spain · Willis Island · St. Tropez, France · Monte Carlo, Monaco · Portofino, Italy · Livorno (Florence/Pisa), Italy · Ajaccio, Corsica, France · Bastia, France · Willis Island · Golfo Arranci, Italy · Civitavecchia (Rome), Italy
★ Bucket-list SintraPrivate Benagil Cave Boat TourReal Alcázar de SevillaTangier Kasbah, Medina & American Legation Private… +16 more
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from $16,849
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Regent · Seven Seas GrandeurOne-way
Mediterranean 10 nights Aug 17 – Aug 27, 2027 from Lisbon, Portugal to Southampton, England
Lisbon, Portugal · Porto (Oporto), Portugal · … · Southampton, England9 ports
Lisbon, Portugal · Porto (Oporto), Portugal · La Coruna, Spain · Bilbao, Spain · Bordeaux, France · Willis Island · St Helier, Isle of Jersey · Le Havre (Paris), France · Southampton, England
★ Bucket-list SintraPrivate Douro Valley Wine TourSantiago de CompostelaGuggenheim Bilbao +5 more
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from $8,499
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Aug 21 – Aug 31, 2027 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,981
Book This Cruise@ Cruisebound
MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Aug 31 – Sep 10, 2027 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,831
Book This Cruise@ Cruisebound
MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Sep 10 – Sep 20, 2027 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Cadiz (Seville), Spain · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,751
Book This Cruise@ Cruisebound
MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 10 nights Sep 20 – Sep 30, 2027 from Lisbon, Portugal
Lisbon, Portugal · Alicante, Spain · … · Lisbon, Portugal9 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Portimao, Portugal · Lisbon, Portugal
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +4 more
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from $1,691
Book This Cruise@ Cruisebound
Regent · Seven Seas VoyagerOne-way
Caribbean 14 nights Sep 27 – Oct 11, 2027 from Lisbon, Portugal to Civitavecchia (Rome), Italy
Lisbon, Portugal · Portimao, Portugal · … · Civitavecchia (Rome), Italy15 ports
Lisbon, Portugal · Portimao, Portugal · Willis Island · Cadiz (Seville), Spain · Tangier, Morocco · Malaga, Spain · Cartagena, Colombia · Willis Island · La Goulette, Tunisia · Trapani, Italy · Valletta, Malta · Messina, Sicily, Italy · Naples, Italy · Olbia, Italy · Civitavecchia (Rome), Italy
★ Bucket-list SintraPrivate Benagil Cave Boat TourZodiac Circumnavigation of Willis IslandReal Alcázar de Sevilla +10 more
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from $10,999
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MSC Cruises · MSC SinfoniaOne-way
Mediterranean 14 nights Sep 30 – Oct 14, 2027 from Lisbon, Portugal to Civitavecchia (Rome), Italy
Lisbon, Portugal · Alicante, Spain · … · Civitavecchia (Rome), Italy12 ports
Lisbon, Portugal · Alicante, Spain · Mahon, Minorca, Spain · Olbia, Italy · Genoa, Italy · Marseille, France · Malaga, Spain · Casablanca, Morocco · Cadiz (Seville), Spain · Gibraltar, British Territory · Alicante, Spain · Civitavecchia (Rome), Italy
★ Bucket-list SintraCastillo de Santa BárbaraPrivate Catamaran SailTavolara Island +7 more
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from $2,282
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MSC Cruises Royal Caribbean Carnival Viking River Costa Norwegian AmaWaterways Princess Celebrity Viking Ocean Avalon Disney Holland America Oceania Virgin Voyages Regent Cunard Seabourn Azamara