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Filtering Visits Civitavecchia (Rome), Italy × Clear all
Showing 72 of 3,983 sailings
Costa · Costa FascinosaOne-way
Mediterranean 5 nights Sep 17 – Sep 22, 2026 from Naples, Italy to Barcelona, Spain
Naples, Italy · Civitavecchia (Rome), Italy · … · Barcelona, Spain6 ports
Naples, Italy · Civitavecchia (Rome), Italy · Ajaccio, Corsica, France · Savona (Genoa), Italy · Marseille, France · Barcelona, Spain
★ Bucket-list Pompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One DaySanguinaires Islands & CalanquesPortofino & San Fruttuoso Abbey by the local ferry +2 more
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from $573
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Costa · Costa SmeraldaRound-trip
Mediterranean 7 nights Sep 17 – Sep 24, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Civitavecchia (Rome), Italy · … · Palermo, Sicily, Italy9 ports
Palermo, Sicily, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Ibiza, Spain · Balearic sea darkest spot · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceVatican, Sistine Chapel & Colosseum in One DayPortofino & San Fruttuoso Abbey by the local ferryCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,103
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Sep 17 – Sep 24, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Genoa, Italy · … · Civitavecchia (Rome), Italy8 ports
Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Sagrada Familia +2 more
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from $755
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MSC Cruises · MSC DivinaRound-trip
Mediterranean 7 nights Sep 17 – Sep 24, 2026 from Naples, Italy
Naples, Italy · Civitavecchia (Rome), Italy · … · Naples, Italy6 ports
Naples, Italy · Civitavecchia (Rome), Italy · Mykonos, Greece · Kusadasi (Ephesus), Turkey · Marmaris, Turkey · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One DayDelosEphesus + the Terrace Houses with a licensed archa… +1 more
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from $822
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 17 – Sep 24, 2026 from Marseille, France
Marseille, France · Tarragona, Spain · … · Marseille, France7 ports
Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Private Roman TarracoOceanograficClimb the Leaning Tower of Pisa +2 more
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from $894
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MSC Cruises · MSC SeaviewRound-trip
Mediterranean 7 nights Sep 17 – Sep 24, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Genoa, Italy · Civitavecchia (Rome), Italy · Palermo, Sicily, Italy · Ibiza, Spain · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $1,231
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Royal Caribbean · Legend Of The SeasRound-trip
Mediterranean 7 nights Sep 17 – Sep 24, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Naples, Italy · … · Civitavecchia (Rome), Italy7 ports
Civitavecchia (Rome), Italy · Naples, Italy · Barcelona, Spain · Palma de Mallorca, Spain · Marseille, France · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistSagrada FamiliaLa Seu Cathedral + Rooftop Terraces Climb +2 more
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from $2,086
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Celebrity · Celebrity AscentRound-trip
Mediterranean 10 nights Sep 18 – Sep 28, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Messina, Sicily, Italy · … · Civitavecchia (Rome), Italy9 ports
Civitavecchia (Rome), Italy · Messina, Sicily, Italy · Katakolon (Olympia), Greece · Corfu, Greece · Dubrovnik, Croatia · Split, Croatia · Bar, Montenegro · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayTaormina's Ancient Greek Theatre, framed by Mount…Ancient OlympiaPaleokastritsa Blue Caves & coves by speedboat +3 more
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from $3,908
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Costa · Costa FascinosaRound-trip
Mediterranean 15 nights Sep 18 – Oct 3, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Ajaccio, Corsica, France · … · Civitavecchia (Rome), Italy13 ports
Civitavecchia (Rome), Italy · Ajaccio, Corsica, France · Savona (Genoa), Italy · Marseille, France · Barcelona, Spain · Palma de Mallorca, Spain · Valletta, Malta · Santorini (Thira), Greece · Mykonos, Greece · Piraeus (Athens), Greece · Souda Bay · Messina, Sicily, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySanguinaires Islands & CalanquesPortofino & San Fruttuoso Abbey by the local ferryCalanques National Park Boat Cruise from the Old P… +8 more
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from $1,927
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Costa · Costa SmeraldaRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Savona (Genoa), Italy · … · Civitavecchia (Rome), Italy9 ports
Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Ibiza, Spain · Balearic sea darkest spot · Palermo, Sicily, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPortofino & San Fruttuoso Abbey by the local ferryCalanques National Park Boat Cruise from the Old P…Sagrada Familia +2 more
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from $655
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy8 ports
Genoa, Italy · Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaSu Nuraxi di Barumini +2 more
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from $721
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MSC Cruises · MSC DivinaRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Mykonos, Greece · … · Civitavecchia (Rome), Italy6 ports
Civitavecchia (Rome), Italy · Mykonos, Greece · Kusadasi (Ephesus), Turkey · Marmaris, Turkey · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayDelosEphesus + the Terrace Houses with a licensed archa…Private Gulet Cruise +1 more
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from $5,016
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MSC Cruises · MSC GrandiosaRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Palma de Mallorca, Spain
Palma de Mallorca, Spain · Barcelona, Spain · … · Palma de Mallorca, Spain7 ports
Palma de Mallorca, Spain · Barcelona, Spain · Cannes, France · Genoa, Italy · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy · Palma de Mallorca, Spain
★ Bucket-list La Seu Cathedral + Rooftop Terraces ClimbSagrada FamiliaPrivate Boat to Îles de LérinsSail straight to Portofino from the cruise dock +2 more
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from $1,155
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Tarragona, Spain
Tarragona, Spain · Valencia, Spain · … · Tarragona, Spain7 ports
Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain
★ Bucket-list Private Roman TarracoOceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $890
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MSC Cruises · MSC SeaviewRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Marseille, France
Marseille, France · Genoa, Italy · … · Marseille, France7 ports
Marseille, France · Genoa, Italy · Civitavecchia (Rome), Italy · Palermo, Sicily, Italy · Ibiza, Spain · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockVatican, Sistine Chapel & Colosseum in One DayCappella Palatina & the Norman Palace +2 more
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from $1,075
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Regent · Seven Seas MarinerOne-way
Mediterranean 11 nights Sep 18 – Sep 29, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Palma de Mallorca, Spain · … · Civitavecchia (Rome), Italy7 ports
Barcelona, Spain · Palma de Mallorca, Spain · Willis Island · Monte Carlo, Monaco · Willis Island · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaLa Seu Cathedral + Rooftop Terraces ClimbZodiac Circumnavigation of Willis IslandCasino de Monte-Carlo +2 more
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from $11,399
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Costa · Costa PacificaRound-trip
Mediterranean 7 nights Sep 19 – Sep 26, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Savona (Genoa), Italy · … · Civitavecchia (Rome), Italy10 ports
Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Toulon, France · Palma bay · Palma de Mallorca, Spain · Valencia, Spain · Palma bay · Balearic sea darkest spot · Olbia, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPortofino & San Fruttuoso Abbey by the local ferryMont FaronLa Seu Cathedral + Rooftop Terraces Climb +2 more
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from $859
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Costa · Costa SmeraldaRound-trip
Mediterranean 7 nights Sep 19 – Sep 26, 2026 from Savona (Genoa), Italy
Savona (Genoa), Italy · Marseille, France · … · Savona (Genoa), Italy9 ports
Savona (Genoa), Italy · Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Ibiza, Spain · Balearic sea darkest spot · Palermo, Sicily, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy
★ Bucket-list Portofino & San Fruttuoso Abbey by the local ferryCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaFormentera Day Trip & Ses Illetes, the 'Spanish Ca… +2 more
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from $641
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Costa · Costa ToscanaOne-way
Mediterranean 5 nights Sep 19 – Sep 24, 2026 from Marseille, France to Civitavecchia (Rome), Italy
Marseille, France · Barcelona, Spain · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaSu Nuraxi di BaruminiPompeii with a Licensed Archaeologist +1 more
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from $917
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MSC Cruises · MSC GrandiosaRound-trip
Mediterranean 7 nights Sep 19 – Sep 26, 2026 from Barcelona, Spain
Barcelona, Spain · Cannes, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Cannes, France · Genoa, Italy · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy · Palma de Mallorca, Spain · Barcelona, Spain
★ Bucket-list Sagrada FamiliaPrivate Boat to Îles de LérinsSail straight to Portofino from the cruise dockPrivate Cinque Terre by Minivan & Ferryboat from L… +2 more
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from $1,193
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 19 – Sep 26, 2026 from Valencia, Spain
Valencia, Spain · Livorno (Florence/Pisa), Italy · … · Valencia, Spain7 ports
Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain
★ Bucket-list OceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dock +2 more
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from $2,008
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MSC Cruises · MSC SeaviewRound-trip
Mediterranean 7 nights Sep 19 – Sep 26, 2026 from Genoa, Italy
Genoa, Italy · Civitavecchia (Rome), Italy · … · Genoa, Italy7 ports
Genoa, Italy · Civitavecchia (Rome), Italy · Palermo, Sicily, Italy · Ibiza, Spain · Barcelona, Spain · Marseille, France · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockVatican, Sistine Chapel & Colosseum in One DayCappella Palatina & the Norman PalaceFormentera Day Trip & Ses Illetes, the 'Spanish Ca… +2 more
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from $926
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Princess · Sun PrincessOne-way
Mediterranean 7 nights Sep 19 – Sep 26, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Ibiza, Spain · … · Civitavecchia (Rome), Italy7 ports
Barcelona, Spain · Ibiza, Spain · Ajaccio, Corsica, France · Marseille, France · Genoa, Italy · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaFormentera Day Trip & Ses Illetes, the 'Spanish Ca…Sanguinaires Islands & CalanquesCalanques National Park Boat Cruise from the Old P… +3 more
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from $1,039
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Carnival · Carnival LegendRound-trip
Mediterranean 12 nights Sep 20, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Kusadasi (Ephesus), Turkey · … · Civitavecchia (Rome), Italy9 ports
Civitavecchia (Rome), Italy · Kusadasi (Ephesus), Turkey · Kavala, Greece · Istanbul, Turkey · Mykonos, Greece · Piraeus (Athens), Greece · Katakolon (Olympia), Greece · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayEphesus + the Terrace Houses with a licensed archa…Ancient PhilippiHagia Sophia + the upper gallery mosaics with a li… +4 more
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from $1,139
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Costa · Costa FascinosaRound-trip
Mediterranean 14 nights Sep 20 – Oct 4, 2026 from Savona (Genoa), Italy
Savona (Genoa), Italy · Marseille, France · … · Savona (Genoa), Italy12 ports
Savona (Genoa), Italy · Marseille, France · Barcelona, Spain · Palma de Mallorca, Spain · Valletta, Malta · Santorini (Thira), Greece · Mykonos, Greece · Piraeus (Athens), Greece · Souda Bay · Messina, Sicily, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy
★ Bucket-list Portofino & San Fruttuoso Abbey by the local ferryCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaLa Seu Cathedral + Rooftop Terraces Climb +7 more
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from $1,457
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Costa · Costa PacificaRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Savona (Genoa), Italy
Savona (Genoa), Italy · Toulon, France · … · Savona (Genoa), Italy10 ports
Savona (Genoa), Italy · Toulon, France · Palma bay · Palma de Mallorca, Spain · Valencia, Spain · Palma bay · Balearic sea darkest spot · Olbia, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy
★ Bucket-list Portofino & San Fruttuoso Abbey by the local ferryMont FaronLa Seu Cathedral + Rooftop Terraces ClimbOceanografic +2 more
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from $865
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Costa · Costa SmeraldaRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Marseille, France
Marseille, France · Barcelona, Spain · … · Marseille, France9 ports
Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Ibiza, Spain · Balearic sea darkest spot · Palermo, Sicily, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaFormentera Day Trip & Ses Illetes, the 'Spanish Ca…Cappella Palatina & the Norman Palace +2 more
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from $1,141
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Barcelona, Spain
Barcelona, Spain · Balearic sea darkest spot · … · Barcelona, Spain8 ports
Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Barcelona, Spain
★ Bucket-list Sagrada FamiliaSu Nuraxi di BaruminiPompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $545
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MSC Cruises · MSC GrandiosaRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Cannes, France
Cannes, France · Genoa, Italy · … · Cannes, France7 ports
Cannes, France · Genoa, Italy · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy · Palma de Mallorca, Spain · Barcelona, Spain · Cannes, France
★ Bucket-list Private Boat to Îles de LérinsSail straight to Portofino from the cruise dockPrivate Cinque Terre by Minivan & Ferryboat from L…Vatican, Sistine Chapel & Colosseum in One Day +2 more
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from $1,006
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MSC Cruises · MSC SeaviewRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Palermo, Sicily, Italy · … · Civitavecchia (Rome), Italy7 ports
Civitavecchia (Rome), Italy · Palermo, Sicily, Italy · Ibiza, Spain · Barcelona, Spain · Marseille, France · Genoa, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayCappella Palatina & the Norman PalaceFormentera Day Trip & Ses Illetes, the 'Spanish Ca…Sagrada Familia +2 more
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from $1,320
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Norwegian · Norwegian EpicOne-way
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Villefranche, France · … · Civitavecchia (Rome), Italy7 ports
Barcelona, Spain · Villefranche, France · Marseille, France · Livorno (Florence/Pisa), Italy · Messina, Sicily, Italy · Salerno, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaPrivate Riviera Half-DayCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +3 more
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from $1,149
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Norwegian · Norwegian GemOne-way
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Civitavecchia (Rome), Italy to Ravenna, Italy
Civitavecchia (Rome), Italy · Salerno, Italy · … · Ravenna, Italy8 ports
Civitavecchia (Rome), Italy · Salerno, Italy · Catania, Sicily, Italy · Corfu, Greece · Kotor, Montenegro · Zadar, Croatia · Venice, Italy · Ravenna, Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayAmalfi Coast Private BoatMount Etna Private Jeep Summit Tour from Catania P…Paleokastritsa Blue Caves & coves by speedboat +4 more
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from $1,009
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Oceania · Oceania SirenaOne-way
Mediterranean 10 nights Sep 20 – Sep 30, 2026 from Valletta, Malta to Barcelona, Spain
Valletta, Malta · Catania, Sicily, Italy · … · Barcelona, Spain11 ports
Valletta, Malta · Catania, Sicily, Italy · Sorrento, Italy · Civitavecchia (Rome), Italy · Olbia, Italy · Portofino, Italy · Villefranche, France · Marseille, France · Port Vendres (Carcassonne), France · Palma de Mallorca, Spain · Barcelona, Spain
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesMount Etna Private Jeep Summit Tour from Catania P…Pompeii Private Excavation Tour with Archaeologist…Vatican, Sistine Chapel & Colosseum in One Day +7 more
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from $3,749
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Royal Caribbean · Legend Of The SeasRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Barcelona, Spain
Barcelona, Spain · Palma de Mallorca, Spain · … · Barcelona, Spain7 ports
Barcelona, Spain · Palma de Mallorca, Spain · Marseille, France · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy · Naples, Italy · Barcelona, Spain
★ Bucket-list Sagrada FamiliaLa Seu Cathedral + Rooftop Terraces ClimbCalanques National Park Boat Cruise from the Old P…Private Cinque Terre by Minivan & Ferryboat from L… +2 more
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from $3,012
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Royal Caribbean · Odyssey of the SeasRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Santorini (Thira), Greece · … · Civitavecchia (Rome), Italy6 ports
Civitavecchia (Rome), Italy · Santorini (Thira), Greece · Ephesus, Turkey · Mykonos, Greece · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySemi-Private Caldera Catamaran with Hot Springs &…Private Ephesus Tour with Expert Local Guide & On-…Delos +1 more
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from $1,897
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Celebrity · Celebrity ConstellationOne-way
Mediterranean 11 nights Sep 21 – Oct 2, 2026 from Civitavecchia (Rome), Italy to Ravenna, Italy
Civitavecchia (Rome), Italy · Florence, Italy · … · Ravenna, Italy9 ports
Civitavecchia (Rome), Italy · Florence, Italy · Amalfi, Italy · Messina, Sicily, Italy · Dubrovnik, Croatia · Bar, Montenegro · Split, Croatia · Zadar, Croatia · Ravenna, Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayUffizi GalleryPrivate Speedboat TourTaormina's Ancient Greek Theatre, framed by Mount… +4 more
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from $2,171
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Costa · Costa FascinosaRound-trip
Mediterranean 16 nights Sep 21 – Oct 7, 2026 from Marseille, France
Marseille, France · Barcelona, Spain · … · Marseille, France13 ports
Marseille, France · Barcelona, Spain · Palma de Mallorca, Spain · Valletta, Malta · Santorini (Thira), Greece · Mykonos, Greece · Piraeus (Athens), Greece · Souda Bay · Messina, Sicily, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaLa Seu Cathedral + Rooftop Terraces ClimbSt John's Co-Cathedral & the Caravaggio masterpieces +7 more
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from $2,179
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Costa · Costa PacificaRound-trip
Mediterranean 7 nights Sep 21 – Sep 28, 2026 from Toulon, France
Toulon, France · Palma de Mallorca, Spain · … · Toulon, France10 ports
Toulon, France · Palma de Mallorca, Spain · Palma bay · Valencia, Spain · Palma bay · Balearic sea darkest spot · Olbia, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Toulon, France
★ Bucket-list Mont FaronLa Seu Cathedral + Rooftop Terraces ClimbOceanograficTavolara Island +2 more
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from $1,070
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Costa · Costa SmeraldaRound-trip
Mediterranean 7 nights Sep 21 – Sep 28, 2026 from Barcelona, Spain
Barcelona, Spain · Balearic sea darkest spot · … · Barcelona, Spain9 ports
Barcelona, Spain · Balearic sea darkest spot · Ibiza, Spain · Balearic sea darkest spot · Palermo, Sicily, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Marseille, France · Barcelona, Spain
★ Bucket-list Sagrada FamiliaFormentera Day Trip & Ses Illetes, the 'Spanish Ca…Cappella Palatina & the Norman PalaceVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $835
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Cunard · Queen VictoriaRound-trip
Mediterranean 14 nights Sep 21 – Oct 5, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Messina, Sicily, Italy · … · Civitavecchia (Rome), Italy12 ports
Civitavecchia (Rome), Italy · Messina, Sicily, Italy · Rhodes, Greece · Ephesus, Turkey · Dardanelles, Turkey · Istanbul, Turkey · Dardanelles, Turkey · Piraeus (Athens), Greece · Souda Bay · Katakolon (Olympia), Greece · Messina, Sicily, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayTaormina's Ancient Greek Theatre, framed by Mount…Private Full-Day Rhodes Island Highlights & LindosPrivate Ephesus Tour with Expert Local Guide & On-… +5 more
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from $2,549
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Explora Journeys · EXPLORA IOne-way
Mediterranean 7 nights Sep 21, 2026 from Civitavecchia (Rome), Italy to Barcelona, Spain
Civitavecchia (Rome), Italy · Marina Grande, Capri, Italy · … · Barcelona, Spain8 ports
Civitavecchia (Rome), Italy · Marina Grande, Capri, Italy · Capri, Italy · Calvi, France · Villefranche, France · La Ciotat, France · Mahon, Minorca, Spain · Barcelona, Spain
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPrivate Boat Circumnavigation of Capri & Blue GrottoPrivate Capri Island Boat Tour + Blue Grotto AccessScandola Nature Reserve & Calanches de Piana +4 more
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from $5,510
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MSC Cruises · MSC DivinaRound-trip
Mediterranean 7 nights Sep 21 – Sep 28, 2026 from Kusadasi (Ephesus), Turkey
Kusadasi (Ephesus), Turkey · Marmaris, Turkey · … · Kusadasi (Ephesus), Turkey6 ports
Kusadasi (Ephesus), Turkey · Marmaris, Turkey · Naples, Italy · Civitavecchia (Rome), Italy · Mykonos, Greece · Kusadasi (Ephesus), Turkey
★ Bucket-list Ephesus + the Terrace Houses with a licensed archa…Private Gulet CruisePompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One Day +1 more
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from $3,184
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MSC Cruises · MSC GrandiosaRound-trip
Mediterranean 7 nights Sep 21 – Sep 28, 2026 from Genoa, Italy
Genoa, Italy · La Spezia (Cinque Terre), Italy · … · Genoa, Italy7 ports
Genoa, Italy · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy · Palma de Mallorca, Spain · Barcelona, Spain · Cannes, France · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockPrivate Cinque Terre by Minivan & Ferryboat from L…Vatican, Sistine Chapel & Colosseum in One DayLa Seu Cathedral + Rooftop Terraces Climb +2 more
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from $1,011
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MSC Cruises · MSC SeaviewRound-trip
Mediterranean 7 nights Sep 21 – Sep 28, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Ibiza, Spain · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Ibiza, Spain · Barcelona, Spain · Marseille, France · Genoa, Italy · Civitavecchia (Rome), Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceFormentera Day Trip & Ses Illetes, the 'Spanish Ca…Sagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $3,950
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Royal Caribbean · Brilliance of the SeasOne-way
Mediterranean 7 nights Sep 21 – Sep 28, 2026 from Ravenna, Italy to Civitavecchia (Rome), Italy
Ravenna, Italy · Dubrovnik, Croatia · … · Civitavecchia (Rome), Italy7 ports
Ravenna, Italy · Dubrovnik, Croatia · Split, Croatia · Sarande, Albania · Messina, Sicily, Italy · Amalfi, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Private Ravenna UNESCO Mosaics Walk with a Local E…Walk Dubrovnik's Ancient City WallsDiocletian's PalaceButrint UNESCO Ruins +3 more
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from $7,230
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Celebrity · Celebrity EquinoxOne-way
Mediterranean 9 nights Sep 22 – Oct 1, 2026 from Civitavecchia (Rome), Italy to Barcelona, Spain
Civitavecchia (Rome), Italy · Naples, Italy · … · Barcelona, Spain7 ports
Civitavecchia (Rome), Italy · Naples, Italy · La Spezia (Cinque Terre), Italy · Portofino, Italy · Villefranche, France · Marseille, France · Barcelona, Spain
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistPrivate Cinque Terre by Minivan & Ferryboat from L…Private Yacht Charter +3 more
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from $1,815
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Costa · Costa FascinosaRound-trip
Mediterranean 14 nights Sep 22 – Oct 6, 2026 from Barcelona, Spain
Barcelona, Spain · Palma de Mallorca, Spain · … · Barcelona, Spain11 ports
Barcelona, Spain · Palma de Mallorca, Spain · Valletta, Malta · Santorini (Thira), Greece · Mykonos, Greece · Piraeus (Athens), Greece · Souda Bay · Messina, Sicily, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Barcelona, Spain
★ Bucket-list Sagrada FamiliaLa Seu Cathedral + Rooftop Terraces ClimbSt John's Co-Cathedral & the Caravaggio masterpiecesSemi-Private Caldera Catamaran with Hot Springs &… +6 more
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from $2,231
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Costa · Costa PacificaOne-way
Mediterranean 7 nights Sep 22 – Sep 29, 2026 from Palma de Mallorca, Spain to Palma de Mallorca, Spain
Palma bay · Palma de Mallorca, Spain · … · Palma de Mallorca, Spain10 ports
Palma bay · Palma de Mallorca, Spain · Valencia, Spain · Palma bay · Balearic sea darkest spot · Olbia, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Toulon, France · Palma de Mallorca, Spain
★ Bucket-list La Seu Cathedral + Rooftop Terraces ClimbOceanograficTavolara IslandVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $1,160
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 22 – Sep 29, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Genoa, Italy · … · Civitavecchia (Rome), Italy7 ports
Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Private Roman Tarraco +2 more
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from $1,135
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Viking Ocean · Viking SeaOne-way
Mediterranean 10 nights Sep 22 – Oct 2, 2026 from Tarragona, Spain to Piraeus (Athens), Greece
Tarragona, Spain · Marseille, France · … · Piraeus (Athens), Greece10 ports
Tarragona, Spain · Marseille, France · Villefranche, France · Florence, Italy · Civitavecchia (Rome), Italy · Naples, Italy · Messina, Sicily, Italy · Sail the Ionian Sea · Heraklion, Crete, Greece · Piraeus (Athens), Greece
★ Bucket-list Private Roman TarracoCalanques National Park Boat Cruise from the Old P…Private Riviera Half-DayUffizi Gallery +5 more
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from $6,599
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Viking Ocean · Viking VestaOne-way
Mediterranean 7 nights Sep 22 – Sep 29, 2026 from Civitavecchia (Rome), Italy to Fusina (Venice), Italy
Civitavecchia (Rome), Italy · Naples, Italy · … · Fusina (Venice), Italy7 ports
Civitavecchia (Rome), Italy · Naples, Italy · Messina, Sicily, Italy · Crotone · Bari, Italy · Sibenik, Croatia · Fusina (Venice), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistTaormina's Ancient Greek Theatre, framed by Mount…Capo Colonna & Santa Severina +3 more
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from $6,499
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Costa · Costa PacificaOne-way
Mediterranean 7 nights Sep 23 – Sep 30, 2026 from Valencia, Spain to Palma bay
Valencia, Spain · Balearic sea darkest spot · … · Palma bay10 ports
Valencia, Spain · Balearic sea darkest spot · Olbia, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Toulon, France · Palma de Mallorca, Spain · Palma bay · Valencia, Spain · Palma bay
★ Bucket-list OceanograficTavolara IslandVatican, Sistine Chapel & Colosseum in One DayPortofino & San Fruttuoso Abbey by the local ferry +2 more
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from $807
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MSC Cruises · MSC GrandiosaRound-trip
Mediterranean 7 nights Sep 23 – Sep 30, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Palma de Mallorca, Spain · … · Civitavecchia (Rome), Italy7 ports
Civitavecchia (Rome), Italy · Palma de Mallorca, Spain · Barcelona, Spain · Cannes, France · Genoa, Italy · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayLa Seu Cathedral + Rooftop Terraces ClimbSagrada FamiliaPrivate Boat to Îles de Lérins +2 more
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from $910
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 23 – Sep 30, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy7 ports
Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Private Roman TarracoOceanografic +2 more
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from $1,147
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Viking Ocean · Viking SkyOne-way
Mediterranean 7 nights Sep 23 – Sep 30, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Sete, France · … · Civitavecchia (Rome), Italy6 ports
Barcelona, Spain · Sete, France · Marseille, France · Monte Carlo, Monaco · Florence, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaPrivate Gastronomic VoyageCalanques National Park Boat Cruise from the Old P…Casino de Monte-Carlo +2 more
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from $5,099
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Costa · Costa SmeraldaRound-trip
Mediterranean 7 nights Sep 24 – Oct 1, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Civitavecchia (Rome), Italy · … · Palermo, Sicily, Italy9 ports
Palermo, Sicily, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Ibiza, Spain · Balearic sea darkest spot · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceVatican, Sistine Chapel & Colosseum in One DayPortofino & San Fruttuoso Abbey by the local ferryCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,063
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Sep 24 – Oct 1, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Genoa, Italy · … · Civitavecchia (Rome), Italy9 ports
Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Balearic sea darkest spot · Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Sagrada Familia +2 more
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from $775
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MSC Cruises · MSC DivinaRound-trip
Mediterranean 7 nights Sep 24 – Oct 1, 2026 from Naples, Italy
Naples, Italy · Civitavecchia (Rome), Italy · … · Naples, Italy6 ports
Naples, Italy · Civitavecchia (Rome), Italy · Mykonos, Greece · Kusadasi (Ephesus), Turkey · Marmaris, Turkey · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistVatican, Sistine Chapel & Colosseum in One DayDelosEphesus + the Terrace Houses with a licensed archa… +1 more
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from $1,845
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 24 – Oct 1, 2026 from Marseille, France
Marseille, France · Tarragona, Spain · … · Marseille, France7 ports
Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Private Roman TarracoOceanograficClimb the Leaning Tower of Pisa +2 more
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from $958
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MSC Cruises · MSC SeaviewRound-trip
Mediterranean 7 nights Sep 24 – Oct 1, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Genoa, Italy · Civitavecchia (Rome), Italy · Palermo, Sicily, Italy · Ibiza, Spain · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $1,006
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Royal Caribbean · Legend Of The SeasRound-trip
Mediterranean 7 nights Sep 24 – Oct 1, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Naples, Italy · … · Civitavecchia (Rome), Italy7 ports
Civitavecchia (Rome), Italy · Naples, Italy · Barcelona, Spain · Palma de Mallorca, Spain · Marseille, France · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPompeii with a Licensed ArchaeologistSagrada FamiliaLa Seu Cathedral + Rooftop Terraces Climb +2 more
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from $2,648
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Costa · Costa SmeraldaOne-way
Mediterranean 2 nights Sep 25 – Sep 27, 2026 from Civitavecchia (Rome), Italy to Marseille, France
Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Marseille, France
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPortofino & San Fruttuoso Abbey by the local ferryCalanques National Park Boat Cruise from the Old P…
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from $397
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy8 ports
Genoa, Italy · Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaSu Nuraxi di Barumini +2 more
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from $711
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MSC Cruises · MSC DivinaRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Mykonos, Greece · … · Civitavecchia (Rome), Italy6 ports
Civitavecchia (Rome), Italy · Mykonos, Greece · Kusadasi (Ephesus), Turkey · Marmaris, Turkey · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayDelosEphesus + the Terrace Houses with a licensed archa…Private Gulet Cruise +1 more
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from $1,115
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MSC Cruises · MSC GrandiosaRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Palma de Mallorca, Spain
Palma de Mallorca, Spain · Barcelona, Spain · … · Palma de Mallorca, Spain7 ports
Palma de Mallorca, Spain · Barcelona, Spain · Cannes, France · Genoa, Italy · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy · Palma de Mallorca, Spain
★ Bucket-list La Seu Cathedral + Rooftop Terraces ClimbSagrada FamiliaPrivate Boat to Îles de LérinsSail straight to Portofino from the cruise dock +2 more
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from $1,015
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Tarragona, Spain
Tarragona, Spain · Valencia, Spain · … · Tarragona, Spain7 ports
Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain
★ Bucket-list Private Roman TarracoOceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $1,303
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MSC Cruises · MSC SeaviewRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Marseille, France
Marseille, France · Genoa, Italy · … · Marseille, France7 ports
Marseille, France · Genoa, Italy · Civitavecchia (Rome), Italy · Palermo, Sicily, Italy · Ibiza, Spain · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockVatican, Sistine Chapel & Colosseum in One DayCappella Palatina & the Norman Palace +2 more
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from $977
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Princess · Enchanted PrincessOne-way
Mediterranean 11 nights Sep 25 – Oct 6, 2026 from Piraeus (Athens), Greece to Civitavecchia (Rome), Italy
Piraeus (Athens), Greece · Santorini (Thira), Greece · … · Civitavecchia (Rome), Italy8 ports
Piraeus (Athens), Greece · Santorini (Thira), Greece · Kusadasi (Ephesus), Turkey · Istanbul, Turkey · Rhodes, Greece · Messina, Sicily, Italy · Valletta, Malta · Civitavecchia (Rome), Italy
★ Bucket-list The Acropolis & Parthenon, Guided Skip-the-LineSemi-Private Caldera Catamaran with Hot Springs &…Ephesus + the Terrace Houses with a licensed archa…Hagia Sophia + the upper gallery mosaics with a li… +4 more
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from $2,711
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Costa · Costa PacificaRound-trip
Mediterranean 7 nights Sep 26 – Oct 3, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Savona (Genoa), Italy · … · Civitavecchia (Rome), Italy10 ports
Civitavecchia (Rome), Italy · Savona (Genoa), Italy · Toulon, France · Palma bay · Palma de Mallorca, Spain · Valencia, Spain · Palma bay · Balearic sea darkest spot · Olbia, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayPortofino & San Fruttuoso Abbey by the local ferryMont FaronLa Seu Cathedral + Rooftop Terraces Climb +2 more
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from $759
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Costa · Costa SmeraldaRound-trip
Mediterranean 7 nights Sep 26 – Oct 3, 2026 from Savona (Genoa), Italy
Savona (Genoa), Italy · Marseille, France · … · Savona (Genoa), Italy9 ports
Savona (Genoa), Italy · Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Ibiza, Spain · Balearic sea darkest spot · Palermo, Sicily, Italy · Civitavecchia (Rome), Italy · Savona (Genoa), Italy
★ Bucket-list Portofino & San Fruttuoso Abbey by the local ferryCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaFormentera Day Trip & Ses Illetes, the 'Spanish Ca… +2 more
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from $711
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Costa · Costa ToscanaRound-trip
Mediterranean 7 nights Sep 26 – Oct 3, 2026 from Marseille, France
Marseille, France · Barcelona, Spain · … · Marseille, France8 ports
Marseille, France · Barcelona, Spain · Balearic sea darkest spot · Cagliari, Sardinia, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaSu Nuraxi di BaruminiPompeii with a Licensed Archaeologist +2 more
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from $992
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MSC Cruises · MSC GrandiosaRound-trip
Mediterranean 7 nights Sep 26 – Oct 3, 2026 from Barcelona, Spain
Barcelona, Spain · Cannes, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Cannes, France · Genoa, Italy · La Spezia (Cinque Terre), Italy · Civitavecchia (Rome), Italy · Palma de Mallorca, Spain · Barcelona, Spain
★ Bucket-list Sagrada FamiliaPrivate Boat to Îles de LérinsSail straight to Portofino from the cruise dockPrivate Cinque Terre by Minivan & Ferryboat from L… +2 more
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from $933
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