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Showing 144 of 1,347 sailings
MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 17 – Sep 24, 2026 from Marseille, France
Marseille, France · Tarragona, Spain · … · Marseille, France7 ports
Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Private Roman TarracoOceanograficClimb the Leaning Tower of Pisa +2 more
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from $894
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 17 – Sep 24, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Valletta, Malta · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,305
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Naples, Italy · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalacePompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,810
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Tarragona, Spain
Tarragona, Spain · Valencia, Spain · … · Tarragona, Spain7 ports
Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain
★ Bucket-list Private Roman TarracoOceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $890
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 18 – Sep 25, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +2 more
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from $1,745
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Regent · Seven Seas MarinerOne-way
Mediterranean 11 nights Sep 18 – Sep 29, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Palma de Mallorca, Spain · … · Civitavecchia (Rome), Italy7 ports
Barcelona, Spain · Palma de Mallorca, Spain · Willis Island · Monte Carlo, Monaco · Willis Island · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaLa Seu Cathedral + Rooftop Terraces ClimbZodiac Circumnavigation of Willis IslandCasino de Monte-Carlo +2 more
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from $11,399
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 19 – Sep 26, 2026 from Naples, Italy
Naples, Italy · Livorno (Florence/Pisa), Italy · … · Naples, Italy7 ports
Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada Familia +2 more
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from $3,670
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 19 – Sep 26, 2026 from Valencia, Spain
Valencia, Spain · Livorno (Florence/Pisa), Italy · … · Valencia, Spain7 ports
Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain
★ Bucket-list OceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dock +2 more
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from $2,008
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Marseille, France · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M… +2 more
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from $2,390
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di Barumini +2 more
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from $2,026
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Norwegian · Norwegian EpicOne-way
Mediterranean 7 nights Sep 20 – Sep 27, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Villefranche, France · … · Civitavecchia (Rome), Italy7 ports
Barcelona, Spain · Villefranche, France · Marseille, France · Livorno (Florence/Pisa), Italy · Messina, Sicily, Italy · Salerno, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaPrivate Riviera Half-DayCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +3 more
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from $1,149
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Celebrity · Celebrity ConstellationOne-way
Mediterranean 11 nights Sep 21 – Oct 2, 2026 from Civitavecchia (Rome), Italy to Ravenna, Italy
Civitavecchia (Rome), Italy · Florence, Italy · … · Ravenna, Italy9 ports
Civitavecchia (Rome), Italy · Florence, Italy · Amalfi, Italy · Messina, Sicily, Italy · Dubrovnik, Croatia · Bar, Montenegro · Split, Croatia · Zadar, Croatia · Ravenna, Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayUffizi GalleryPrivate Speedboat TourTaormina's Ancient Greek Theatre, framed by Mount… +4 more
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from $2,171
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 21 – Sep 28, 2026 from Marseille, France
Marseille, France · Barcelona, Spain · … · Marseille, France7 ports
Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M…Cappella Palatina & the Norman Palace +2 more
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from $1,203
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 21 – Sep 28, 2026 from Marseille, France
Marseille, France · Livorno (Florence/Pisa), Italy · … · Marseille, France7 ports
Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman Palace +2 more
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from $1,277
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 22 – Sep 29, 2026 from Barcelona, Spain
Barcelona, Spain · La Goulette, Tunisia · … · Barcelona, Spain7 ports
Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain
★ Bucket-list Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M…Cappella Palatina & the Norman PalacePompeii with a Licensed Archaeologist +2 more
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from $2,549
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 22 – Sep 29, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Genoa, Italy · … · Civitavecchia (Rome), Italy7 ports
Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Private Roman Tarraco +2 more
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from $1,135
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 22 – Sep 29, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,153
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Viking Ocean · Viking SeaOne-way
Mediterranean 10 nights Sep 22 – Oct 2, 2026 from Tarragona, Spain to Piraeus (Athens), Greece
Tarragona, Spain · Marseille, France · … · Piraeus (Athens), Greece10 ports
Tarragona, Spain · Marseille, France · Villefranche, France · Florence, Italy · Civitavecchia (Rome), Italy · Naples, Italy · Messina, Sicily, Italy · Sail the Ionian Sea · Heraklion, Crete, Greece · Piraeus (Athens), Greece
★ Bucket-list Private Roman TarracoCalanques National Park Boat Cruise from the Old P…Private Riviera Half-DayUffizi Gallery +5 more
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from $6,599
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 23 – Sep 30, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy7 ports
Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Private Roman TarracoOceanografic +2 more
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from $1,147
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 23 – Sep 30, 2026 from Cagliari, Sardinia, Italy
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · … · Cagliari, Sardinia, Italy7 ports
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy
★ Bucket-list Su Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,363
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Viking Ocean · Viking SkyOne-way
Mediterranean 7 nights Sep 23 – Sep 30, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Sete, France · … · Civitavecchia (Rome), Italy6 ports
Barcelona, Spain · Sete, France · Marseille, France · Monte Carlo, Monaco · Florence, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaPrivate Gastronomic VoyageCalanques National Park Boat Cruise from the Old P…Casino de Monte-Carlo +2 more
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from $5,099
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 24 – Oct 1, 2026 from Marseille, France
Marseille, France · Tarragona, Spain · … · Marseille, France7 ports
Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Private Roman TarracoOceanograficClimb the Leaning Tower of Pisa +2 more
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from $958
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 24 – Oct 1, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Valletta, Malta · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $2,094
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Naples, Italy · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalacePompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P… +2 more
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from $2,697
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Tarragona, Spain
Tarragona, Spain · Valencia, Spain · … · Tarragona, Spain7 ports
Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain
★ Bucket-list Private Roman TarracoOceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $1,303
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 25 – Oct 2, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +2 more
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from $2,094
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 26 – Oct 3, 2026 from Naples, Italy
Naples, Italy · Livorno (Florence/Pisa), Italy · … · Naples, Italy7 ports
Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada Familia +2 more
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from $2,640
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 26 – Oct 3, 2026 from Valencia, Spain
Valencia, Spain · Livorno (Florence/Pisa), Italy · … · Valencia, Spain7 ports
Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain
★ Bucket-list OceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dock +2 more
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from $1,322
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Viking Ocean · Viking NeptuneOne-way
Mediterranean 7 nights Sep 26 – Oct 3, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Tarragona, Spain · … · Civitavecchia (Rome), Italy7 ports
Barcelona, Spain · Tarragona, Spain · Sete, France · Marseille, France · Monte Carlo, Monaco · Florence, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaPrivate Roman TarracoPrivate Gastronomic VoyageCalanques National Park Boat Cruise from the Old P… +3 more
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from $4,899
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 27 – Oct 4, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Marseille, France · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M… +2 more
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from $957
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 27 – Oct 4, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di Barumini +2 more
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from $1,118
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Norwegian · Norwegian EpicOne-way
Mediterranean 7 nights Sep 27 – Oct 4, 2026 from Civitavecchia (Rome), Italy to Barcelona, Spain
Civitavecchia (Rome), Italy · Salerno, Italy · … · Barcelona, Spain7 ports
Civitavecchia (Rome), Italy · Salerno, Italy · Catania, Sicily, Italy · Livorno (Florence/Pisa), Italy · Villefranche, France · Marseille, France · Barcelona, Spain
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayAmalfi Coast Private BoatMount Etna Private Jeep Summit Tour from Catania P…Climb the Leaning Tower of Pisa +3 more
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from $1,009
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 28 – Oct 5, 2026 from Marseille, France
Marseille, France · Barcelona, Spain · … · Marseille, France7 ports
Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M…Cappella Palatina & the Norman Palace +2 more
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from $710
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 28 – Oct 5, 2026 from Marseille, France
Marseille, France · Livorno (Florence/Pisa), Italy · … · Marseille, France7 ports
Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman Palace +2 more
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from $1,320
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Silversea · Silver SpiritOne-way
Mediterranean 10 nights Sep 28 – Oct 8, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Palamos, Spain · … · Civitavecchia (Rome), Italy9 ports
Barcelona, Spain · Palamos, Spain · Palma de Mallorca, Spain · Sete, France · Marseille, France · Monte Carlo, Monaco · Livorno (Florence/Pisa), Italy · Porto Santo Stefano, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaGironaLa Seu Cathedral + Rooftop Terraces ClimbPrivate Gastronomic Voyage +5 more
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from $9,050
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Sep 29 – Oct 6, 2026 from Barcelona, Spain
Barcelona, Spain · La Goulette, Tunisia · … · Barcelona, Spain7 ports
Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain
★ Bucket-list Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M…Cappella Palatina & the Norman PalacePompeii with a Licensed Archaeologist +2 more
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from $1,251
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 29 – Oct 6, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Genoa, Italy · … · Civitavecchia (Rome), Italy7 ports
Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Private Roman Tarraco +2 more
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from $1,720
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 29 – Oct 6, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,027
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Sep 30 – Oct 7, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy7 ports
Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Private Roman TarracoOceanografic +2 more
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from $839
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Sep 30 – Oct 7, 2026 from Cagliari, Sardinia, Italy
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · … · Cagliari, Sardinia, Italy7 ports
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy
★ Bucket-list Su Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,748
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Oct 1 – Oct 8, 2026 from Marseille, France
Marseille, France · Tarragona, Spain · … · Marseille, France7 ports
Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Private Roman TarracoOceanograficClimb the Leaning Tower of Pisa +2 more
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from $3,769
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 1 – Oct 8, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Valletta, Malta · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,146
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Oct 2 – Oct 9, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Naples, Italy · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalacePompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P… +2 more
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from $929
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Oct 2 – Oct 9, 2026 from Tarragona, Spain
Tarragona, Spain · Valencia, Spain · … · Tarragona, Spain7 ports
Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain
★ Bucket-list Private Roman TarracoOceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $787
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 2 – Oct 9, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +2 more
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from $1,476
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Oct 3 – Oct 10, 2026 from Naples, Italy
Naples, Italy · Livorno (Florence/Pisa), Italy · … · Naples, Italy7 ports
Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada Familia +2 more
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from $1,163
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Oct 3 – Oct 10, 2026 from Valencia, Spain
Valencia, Spain · Livorno (Florence/Pisa), Italy · … · Valencia, Spain7 ports
Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain
★ Bucket-list OceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dock +2 more
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from $1,005
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Oct 4 – Oct 11, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Marseille, France · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M… +2 more
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from $979
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 4 – Oct 11, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di Barumini +2 more
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from $1,170
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Norwegian · Norwegian EpicOne-way
Mediterranean 7 nights Oct 4 – Oct 11, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Marseille, France · … · Civitavecchia (Rome), Italy7 ports
Barcelona, Spain · Marseille, France · Villefranche, France · Livorno (Florence/Pisa), Italy · Messina, Sicily, Italy · Salerno, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Private Riviera Half-DayClimb the Leaning Tower of Pisa +3 more
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from $739
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Oct 5 – Oct 12, 2026 from Marseille, France
Marseille, France · Barcelona, Spain · … · Marseille, France7 ports
Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M…Cappella Palatina & the Norman Palace +2 more
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from $3,680
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 5 – Oct 12, 2026 from Marseille, France
Marseille, France · Livorno (Florence/Pisa), Italy · … · Marseille, France7 ports
Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman Palace +2 more
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from $1,216
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Oct 6 – Oct 13, 2026 from Barcelona, Spain
Barcelona, Spain · La Goulette, Tunisia · … · Barcelona, Spain7 ports
Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain
★ Bucket-list Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M…Cappella Palatina & the Norman PalacePompeii with a Licensed Archaeologist +2 more
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from $934
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Oct 6 – Oct 13, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Genoa, Italy · … · Civitavecchia (Rome), Italy7 ports
Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Private Roman Tarraco +2 more
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from $949
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 6 – Oct 13, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,788
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Oct 7 – Oct 14, 2026 from Genoa, Italy
Genoa, Italy · Marseille, France · … · Genoa, Italy7 ports
Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Private Roman TarracoOceanografic +2 more
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from $731
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 7 – Oct 14, 2026 from Cagliari, Sardinia, Italy
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · … · Cagliari, Sardinia, Italy7 ports
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy
★ Bucket-list Su Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,246
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Viking Ocean · Viking JupiterOne-way
Mediterranean 7 nights Oct 7 – Oct 14, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Sete, France · … · Civitavecchia (Rome), Italy6 ports
Barcelona, Spain · Sete, France · Marseille, France · Monte Carlo, Monaco · Florence, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaPrivate Gastronomic VoyageCalanques National Park Boat Cruise from the Old P…Casino de Monte-Carlo +2 more
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from $4,499
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Holland America · VolendamRound-trip
Mediterranean 45 nights Oct 8 – Nov 22, 2026 from New York, New York
New York, New York · Ponta Delgada, Azores, Portugal · … · New York, New York23 ports
New York, New York · Ponta Delgada, Azores, Portugal · Lisbon, Portugal · Cartagena, Spain · Barcelona, Spain · Villefranche, France · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Naples, Italy · Messina, Sicily, Italy · Kefalonia, Greece · Iraklion (Heraklion), Crete, Greece · Rhodes, Greece · Bodrum, Turkey · Kusadasi (Ephesus), Turkey · Istanbul, Turkey · Piraeus (Athens), Greece · Valletta, Malta · La Goulette, Tunisia · Malaga, Spain · Cadiz (Seville), Spain · Funchal, Madeira, Portugal · New York, New York
★ Bucket-list Manhattan Helicopter TourSete Cidades Twin LakesSintraThe Roman Theatre of Cartagena with the Rafael Mon… +18 more
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from $6,224
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Oct 8 – Oct 15, 2026 from Marseille, France
Marseille, France · Tarragona, Spain · … · Marseille, France7 ports
Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Private Roman TarracoOceanograficClimb the Leaning Tower of Pisa +2 more
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from $1,132
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 8 – Oct 15, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Valletta, Malta · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,150
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Silversea · Silver RayOne-way
Mediterranean 10 nights Oct 8 – Oct 18, 2026 from Monte Carlo, Monaco to Civitavecchia (Rome), Italy
Monte Carlo, Monaco · Toulon, France · … · Civitavecchia (Rome), Italy10 ports
Monte Carlo, Monaco · Toulon, France · Ajaccio, Corsica, France · Porto Santo Stefano, Italy · Portoferraio (Elba), Italy · Livorno (Florence/Pisa), Italy · Portofino, Italy · Trapani, Italy · Naples, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Casino de Monte-CarloMont FaronSanguinaires Islands & CalanquesPrivate Sailing Day Around Giglio Island & Secret… +6 more
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from $10,450
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Carnival · Carnival FreedomRound-trip
Mediterranean 8 nights Oct 9, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Naples, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $799
Book This Cruise@ Cruisebound
MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Oct 9 – Oct 16, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Naples, Italy · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalacePompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,466
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Oct 9 – Oct 16, 2026 from Tarragona, Spain
Tarragona, Spain · Valencia, Spain · … · Tarragona, Spain7 ports
Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain
★ Bucket-list Private Roman TarracoOceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $741
Book This Cruise@ Cruisebound
MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 9 – Oct 16, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +2 more
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from $1,016
Book This Cruise@ Cruisebound
MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Oct 10 – Oct 17, 2026 from Naples, Italy
Naples, Italy · Livorno (Florence/Pisa), Italy · … · Naples, Italy7 ports
Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy
★ Bucket-list Pompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada Familia +2 more
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from $874
Book This Cruise@ Cruisebound
MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Oct 10 – Oct 17, 2026 from Valencia, Spain
Valencia, Spain · Livorno (Florence/Pisa), Italy · … · Valencia, Spain7 ports
Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain
★ Bucket-list OceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dock +2 more
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from $1,253
Book This Cruise@ Cruisebound
MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 11 – Oct 18, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di Barumini +2 more
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from $1,281
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Norwegian · Norwegian EpicOne-way
Mediterranean 7 nights Oct 11 – Oct 18, 2026 from Civitavecchia (Rome), Italy to Barcelona, Spain
Civitavecchia (Rome), Italy · Salerno, Italy · … · Barcelona, Spain7 ports
Civitavecchia (Rome), Italy · Salerno, Italy · Catania, Sicily, Italy · Livorno (Florence/Pisa), Italy · Villefranche, France · Marseille, France · Barcelona, Spain
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayAmalfi Coast Private BoatMount Etna Private Jeep Summit Tour from Catania P…Climb the Leaning Tower of Pisa +3 more
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from $689
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Celebrity · Celebrity ConstellationOne-way
Mediterranean 11 nights Oct 12 – Oct 23, 2026 from Civitavecchia (Rome), Italy to Ravenna, Italy
Civitavecchia (Rome), Italy · Florence, Italy · … · Ravenna, Italy9 ports
Civitavecchia (Rome), Italy · Florence, Italy · Amalfi, Italy · Messina, Sicily, Italy · Kotor, Montenegro · Brindisi, Italy · Split, Croatia · Zadar, Croatia · Ravenna, Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayUffizi GalleryPrivate Speedboat TourTaormina's Ancient Greek Theatre, framed by Mount… +5 more
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from $1,741
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Oct 12 – Oct 19, 2026 from Marseille, France
Marseille, France · Barcelona, Spain · … · Marseille, France7 ports
Marseille, France · Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M…Cappella Palatina & the Norman Palace +2 more
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from $2,678
Book This Cruise@ Cruisebound
MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 12 – Oct 19, 2026 from Marseille, France
Marseille, France · Livorno (Florence/Pisa), Italy · … · Marseille, France7 ports
Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman Palace +2 more
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from $1,119
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Oceania · Oceania SirenaOne-way
Mediterranean 7 nights Oct 12 – Oct 19, 2026 from Civitavecchia (Rome), Italy to Monte Carlo, Monaco
Civitavecchia (Rome), Italy · Florence, Italy · … · Monte Carlo, Monaco8 ports
Civitavecchia (Rome), Italy · Florence, Italy · Porto Torres(sardinia),italy · Mahon, Minorca, Spain · Barcelona, Spain · Sete, France · Toulon, France · Monte Carlo, Monaco
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayUffizi GalleryAsinara National ParkPrivate Catamaran Sail +4 more
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from $7,099
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Viking Ocean · Viking StarOne-way
Mediterranean 12 nights Oct 12 – Oct 24, 2026 from Chioggia, Venice, Italy to Tarragona, Spain
Chioggia, Venice, Italy · Split, Croatia · … · Tarragona, Spain11 ports
Chioggia, Venice, Italy · Split, Croatia · Dubrovnik, Croatia · Corfu, Greece · Sail the Ionian Sea · Naples, Italy · Civitavecchia (Rome), Italy · Florence, Italy · Villefranche, France · Marseille, France · Tarragona, Spain
★ Bucket-list VeniceDiocletian's PalaceWalk Dubrovnik's Ancient City WallsPaleokastritsa Blue Caves & coves by speedboat +6 more
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from $9,199
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MSC Cruises · MSC MeravigliaRound-trip
Mediterranean 7 nights Oct 13 – Oct 20, 2026 from Barcelona, Spain
Barcelona, Spain · La Goulette, Tunisia · … · Barcelona, Spain7 ports
Barcelona, Spain · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain
★ Bucket-list Sagrada FamiliaPrivate Full-Day Carthage, Sidi Bou Said & Bardo M…Cappella Palatina & the Norman PalacePompeii with a Licensed Archaeologist +2 more
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from $1,061
Book This Cruise@ Cruisebound
MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Oct 13 – Oct 20, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Genoa, Italy · … · Civitavecchia (Rome), Italy7 ports
Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Private Roman Tarraco +2 more
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from $1,119
Book This Cruise@ Cruisebound
MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 13 – Oct 20, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,063
Book This Cruise@ Cruisebound
MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 14 – Oct 21, 2026 from Cagliari, Sardinia, Italy
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · … · Cagliari, Sardinia, Italy7 ports
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy
★ Bucket-list Su Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,772
Book This Cruise@ Cruisebound
Viking Ocean · Viking MiraOne-way
Mediterranean 7 nights Oct 14 – Oct 21, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Sete, France · … · Civitavecchia (Rome), Italy6 ports
Barcelona, Spain · Sete, France · Marseille, France · Monte Carlo, Monaco · Florence, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaPrivate Gastronomic VoyageCalanques National Park Boat Cruise from the Old P…Casino de Monte-Carlo +2 more
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from $4,099
Book This Cruise@ Cruisebound
MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Oct 15 – Oct 22, 2026 from Marseille, France
Marseille, France · Tarragona, Spain · … · Marseille, France7 ports
Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Private Roman TarracoOceanograficClimb the Leaning Tower of Pisa +2 more
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from $1,162
Book This Cruise@ Cruisebound
MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 15 – Oct 22, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Valletta, Malta · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,338
Book This Cruise@ Cruisebound
Viking Ocean · Viking VestaOne-way
Mediterranean 12 nights Oct 15 – Oct 27, 2026 from Fusina (Venice), Italy to Barcelona, Spain
Fusina (Venice), Italy · Split, Croatia · … · Barcelona, Spain11 ports
Fusina (Venice), Italy · Split, Croatia · Dubrovnik, Croatia · Corfu, Greece · Sail the Ionian Sea · Naples, Italy · Civitavecchia (Rome), Italy · Florence, Italy · Villefranche, France · Marseille, France · Barcelona, Spain
★ Bucket-list Private Gondola RideDiocletian's PalaceWalk Dubrovnik's Ancient City WallsPaleokastritsa Blue Caves & coves by speedboat +6 more
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from $8,999
Book This Cruise@ Cruisebound
MSC Cruises · MSC MeravigliaOne-way
Mediterranean 26 nights Oct 16 – Nov 11, 2026 from Palermo, Sicily, Italy to Miami, Florida
Palermo, Sicily, Italy · Naples, Italy · … · Miami, Florida15 ports
Palermo, Sicily, Italy · Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · Alicante, Spain · Gibraltar, British Territory · Cadiz (Seville), Spain · Casablanca, Morocco · Las Palmas, Gran Canaria, Canary Islands · Funchal, Madeira, Portugal · Ponta Delgada, Azores, Portugal · Boston, Massachusetts · Brooklyn, NY · Miami, Florida
★ Bucket-list Cappella Palatina & the Norman PalacePompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P… +11 more
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from $2,689
Book This Cruise@ Cruisebound
MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Oct 16 – Oct 23, 2026 from Tarragona, Spain
Tarragona, Spain · Valencia, Spain · … · Tarragona, Spain7 ports
Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain
★ Bucket-list Private Roman TarracoOceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $1,144
Book This Cruise@ Cruisebound
MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 16 – Oct 23, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +2 more
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from $1,006
Book This Cruise@ Cruisebound
Viking Ocean · Viking SeaRepositioning
Caribbean 20 nights Oct 16 – Nov 5, 2026 from Civitavecchia (Rome), Italy to San Juan, Puerto Rico
Civitavecchia (Rome), Italy · Florence, Italy · … · San Juan, Puerto Rico13 ports
Civitavecchia (Rome), Italy · Florence, Italy · Monte Carlo, Monaco · Marseille, France · Sete, France · Barcelona, Spain · Valencia, Spain · Sail the Alboran Sea · Sail the Atlantic Ocean · Funchal, Madeira, Portugal · Sail the Atlantic Ocean · Philipsburg, St. Maarten · San Juan, Puerto Rico
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayUffizi GalleryCasino de Monte-CarloCalanques National Park Boat Cruise from the Old P… +6 more
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from $7,398
Book This Cruise@ Cruisebound
MSC Cruises · MSC MeravigliaRepositioning
Mediterranean 25 nights Oct 17 – Nov 11, 2026 from Naples, Italy to Miami, Florida
Naples, Italy · Livorno (Florence/Pisa), Italy · … · Miami, Florida14 ports
Naples, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · Alicante, Spain · Gibraltar, British Territory · Cadiz (Seville), Spain · Casablanca, Morocco · Las Palmas, Gran Canaria, Canary Islands · Funchal, Madeira, Portugal · Ponta Delgada, Azores, Portugal · Boston, Massachusetts · Brooklyn, NY · Miami, Florida
★ Bucket-list Pompeii with a Licensed ArchaeologistClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada Familia +10 more
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from $2,044
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Oct 17 – Oct 24, 2026 from Valencia, Spain
Valencia, Spain · Livorno (Florence/Pisa), Italy · … · Valencia, Spain7 ports
Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain
★ Bucket-list OceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dock +2 more
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from $1,136
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Oceania · Oceania AlluraOne-way
Mediterranean 14 nights Oct 17 – Oct 31, 2026 from Istanbul, Turkey to Barcelona, Spain
Istanbul, Turkey · Mykonos, Greece · … · Barcelona, Spain14 ports
Istanbul, Turkey · Mykonos, Greece · Katakolon (Olympia), Greece · Corfu, Greece · Dubrovnik, Croatia · Kotor, Montenegro · Messina, Sicily, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Florence, Italy · Toulon, France · Marseille, France · Palma de Mallorca, Spain · Barcelona, Spain
★ Bucket-list Hagia Sophia + the upper gallery mosaics with a li…DelosAncient OlympiaPaleokastritsa Blue Caves & coves by speedboat +10 more
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from $9,599
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Viking Ocean · Viking SaturnOne-way
Mediterranean 7 nights Oct 17 – Oct 24, 2026 from Tarragona, Spain to Civitavecchia (Rome), Italy
Tarragona, Spain · Sete, France · … · Civitavecchia (Rome), Italy6 ports
Tarragona, Spain · Sete, France · Marseille, France · Monte Carlo, Monaco · Florence, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Private Roman TarracoPrivate Gastronomic VoyageCalanques National Park Boat Cruise from the Old P…Casino de Monte-Carlo +2 more
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from $3,999
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MSC Cruises · MSC MeravigliaRepositioning
Mediterranean 24 nights Oct 18 – Nov 11, 2026 from Livorno (Florence/Pisa), Italy to Miami, Florida
Livorno (Florence/Pisa), Italy · Marseille, France · … · Miami, Florida13 ports
Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · Alicante, Spain · Gibraltar, British Territory · Cadiz (Seville), Spain · Casablanca, Morocco · Las Palmas, Gran Canaria, Canary Islands · Funchal, Madeira, Portugal · Ponta Delgada, Azores, Portugal · Boston, Massachusetts · Brooklyn, NY · Miami, Florida
★ Bucket-list Climb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaCastillo de Santa Bárbara +9 more
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from $2,649
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 18 – Oct 25, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di Barumini +2 more
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from $1,356
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Norwegian · Norwegian EpicOne-way
Mediterranean 7 nights Oct 18 – Oct 25, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Marseille, France · … · Civitavecchia (Rome), Italy7 ports
Barcelona, Spain · Marseille, France · Villefranche, France · Livorno (Florence/Pisa), Italy · Messina, Sicily, Italy · Salerno, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Private Riviera Half-DayClimb the Leaning Tower of Pisa +3 more
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from $699
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 19 – Oct 26, 2026 from Marseille, France
Marseille, France · Livorno (Florence/Pisa), Italy · … · Marseille, France7 ports
Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman Palace +2 more
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from $1,223
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MSC Cruises · MSC OrchestraRound-trip
Mediterranean 7 nights Oct 20 – Oct 27, 2026 from Civitavecchia (Rome), Italy
Civitavecchia (Rome), Italy · Genoa, Italy · … · Civitavecchia (Rome), Italy7 ports
Civitavecchia (Rome), Italy · Genoa, Italy · Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dockCalanques National Park Boat Cruise from the Old P…Private Roman Tarraco +2 more
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from $3,603
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 20 – Oct 27, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,899
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Princess · Enchanted PrincessOne-way
Mediterranean 11 nights Oct 20 – Oct 31, 2026 from Civitavecchia (Rome), Italy to Piraeus (Athens), Greece
Civitavecchia (Rome), Italy · Sardinia, Italy · … · Piraeus (Athens), Greece10 ports
Civitavecchia (Rome), Italy · Sardinia, Italy · Genoa, Italy · Florence, Italy · Valletta, Malta · Messina, Sicily, Italy · Mykonos, Greece · Rhodes, Greece · Kusadasi (Ephesus), Turkey · Piraeus (Athens), Greece
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayLa Maddalena ArchipelagoSail straight to Portofino from the cruise dockUffizi Gallery +6 more
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from $1,514
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 21 – Oct 28, 2026 from Cagliari, Sardinia, Italy
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · … · Cagliari, Sardinia, Italy7 ports
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy
★ Bucket-list Su Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,323
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MSC Cruises · MSC OrchestraOne-way
Mediterranean 9 nights Oct 22 – Oct 31, 2026 from Marseille, France to Bari, Italy
Marseille, France · Tarragona, Spain · … · Bari, Italy9 ports
Marseille, France · Tarragona, Spain · Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Catania, Sicily, Italy · Corfu, Greece · Kotor, Montenegro · Bari, Italy
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Private Roman TarracoOceanograficClimb the Leaning Tower of Pisa +5 more
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from $1,282
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 22 – Oct 29, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Valletta, Malta · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,725
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 23 – Oct 30, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +2 more
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from $1,139
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MSC Cruises · MSC OrchestraOne-way
Mediterranean 3 nights Oct 24 – Oct 27, 2026 from Valencia, Spain to Civitavecchia (Rome), Italy
Valencia, Spain · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy
★ Bucket-list OceanograficClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One Day
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from $519
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Viking Ocean · Viking StarOne-way
Mediterranean 7 nights Oct 24 – Oct 31, 2026 from Tarragona, Spain to Civitavecchia (Rome), Italy
Tarragona, Spain · Sete, France · … · Civitavecchia (Rome), Italy6 ports
Tarragona, Spain · Sete, France · Marseille, France · Monte Carlo, Monaco · Florence, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Private Roman TarracoPrivate Gastronomic VoyageCalanques National Park Boat Cruise from the Old P…Casino de Monte-Carlo +2 more
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from $3,799
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 25 – Nov 1, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di Barumini +2 more
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from $1,022
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Norwegian · Norwegian EpicOne-way
Mediterranean 7 nights Oct 25 – Nov 1, 2026 from Civitavecchia (Rome), Italy to Barcelona, Spain
Civitavecchia (Rome), Italy · Salerno, Italy · … · Barcelona, Spain7 ports
Civitavecchia (Rome), Italy · Salerno, Italy · Catania, Sicily, Italy · Livorno (Florence/Pisa), Italy · Villefranche, France · Marseille, France · Barcelona, Spain
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayAmalfi Coast Private BoatMount Etna Private Jeep Summit Tour from Catania P…Climb the Leaning Tower of Pisa +3 more
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from $629
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 26 – Nov 2, 2026 from Marseille, France
Marseille, France · Livorno (Florence/Pisa), Italy · … · Marseille, France7 ports
Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman Palace +2 more
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from $1,116
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 27 – Nov 3, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $1,084
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Viking Ocean · Viking VelaOne-way
Mediterranean 7 nights Oct 27 – Nov 3, 2026 from Tarragona, Spain to Civitavecchia (Rome), Italy
Tarragona, Spain · Sete, France · … · Civitavecchia (Rome), Italy6 ports
Tarragona, Spain · Sete, France · Marseille, France · Monte Carlo, Monaco · Florence, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Private Roman TarracoPrivate Gastronomic VoyageCalanques National Park Boat Cruise from the Old P…Casino de Monte-Carlo +2 more
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from $3,749
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 28 – Nov 4, 2026 from Cagliari, Sardinia, Italy
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · … · Cagliari, Sardinia, Italy7 ports
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy
★ Bucket-list Su Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,155
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MSC Cruises · MSC OperaOne-way
Mediterranean 25 nights Oct 29 – Nov 23, 2026 from Civitavecchia (Rome), Italy to La Romana, Dominican Republic
Civitavecchia (Rome), Italy · Genoa, Italy · … · La Romana, Dominican Republic16 ports
Civitavecchia (Rome), Italy · Genoa, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · Tangier, Morocco · St. John's, Antigua · Philipsburg, St. Maarten · Port of Charlestown, Nevis, St. Kitts and Nevis · La Romana, Dominican Republic · Catalina Island, Dominican Republic · Bridgetown, Barbados · Fort-de-France, Martinique · Pointe-a-Pitre, Guadeloupe · Road Town, Tortola, B.V.I. · La Romana, Dominican Republic
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DaySail straight to Portofino from the cruise dockClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P… +10 more
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from $4,730
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 29 – Nov 5, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Valletta, Malta · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $1,920
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MSC Cruises · MSC OperaRepositioning
Mediterranean 17 nights Oct 30 – Nov 16, 2026 from Genoa, Italy to La Romana, Dominican Republic
Genoa, Italy · Livorno (Florence/Pisa), Italy · … · La Romana, Dominican Republic9 ports
Genoa, Italy · Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · Tangier, Morocco · St. John's, Antigua · Philipsburg, St. Maarten · Port of Charlestown, Nevis, St. Kitts and Nevis · La Romana, Dominican Republic
★ Bucket-list Sail straight to Portofino from the cruise dockClimb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada Familia +5 more
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from $629
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Oct 30 – Nov 6, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +2 more
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from $943
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Azamara · Azamara OnwardOne-way
Mediterranean 7 nights Oct 31 – Nov 7, 2026 from Civitavecchia (Rome), Italy to Barcelona, Spain
Civitavecchia (Rome), Italy · Florence, Italy · … · Barcelona, Spain7 ports
Civitavecchia (Rome), Italy · Florence, Italy · Monte Carlo, Monaco · Nice, France · Marseille, France · Palamos, Spain · Barcelona, Spain
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayUffizi GalleryCasino de Monte-CarloFrench Riviera by Private Yacht +3 more
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from $2,219
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MSC Cruises · MSC OperaOne-way
Mediterranean 16 nights Oct 31 – Nov 16, 2026 from Livorno (Florence/Pisa), Italy to La Romana, Dominican Republic
Livorno (Florence/Pisa), Italy · Marseille, France · … · La Romana, Dominican Republic8 ports
Livorno (Florence/Pisa), Italy · Marseille, France · Barcelona, Spain · Tangier, Morocco · St. John's, Antigua · Philipsburg, St. Maarten · Port of Charlestown, Nevis, St. Kitts and Nevis · La Romana, Dominican Republic
★ Bucket-list Climb the Leaning Tower of PisaCalanques National Park Boat Cruise from the Old P…Sagrada FamiliaTangier Kasbah, Medina & American Legation Private… +4 more
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from $1,729
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 6 nights Oct 31 – Nov 6, 2026 from Valencia, Spain
Valencia, Spain · Tarragona, Spain · … · Valencia, Spain6 ports
Valencia, Spain · Tarragona, Spain · Marseille, France · Genoa, Italy · Livorno (Florence/Pisa), Italy · Valencia, Spain
★ Bucket-list OceanograficPrivate Roman TarracoCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dock +1 more
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from $438
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Viking Ocean · Viking SaturnOne-way
Mediterranean 7 nights Oct 31 – Nov 7, 2026 from Tarragona, Spain to Civitavecchia (Rome), Italy
Tarragona, Spain · Sete, France · … · Civitavecchia (Rome), Italy6 ports
Tarragona, Spain · Sete, France · Marseille, France · Monte Carlo, Monaco · Florence, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Private Roman TarracoPrivate Gastronomic VoyageCalanques National Park Boat Cruise from the Old P…Casino de Monte-Carlo +2 more
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from $3,399
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MSC Cruises · MSC SinfoniaOne-way
Mediterranean 7 nights Nov 1 – Nov 8, 2026 from Tarragona, Spain to Barcelona, Spain
Tarragona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Tarragona, Spain · Marseille, France · Genoa, Italy · Livorno (Florence/Pisa), Italy · Valencia, Spain · Palma de Mallorca, Spain · Barcelona, Spain
★ Bucket-list Private Roman TarracoCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockClimb the Leaning Tower of Pisa +3 more
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from $519
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Nov 1 – Nov 8, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di Barumini +2 more
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from $1,038
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Regent · Seven Seas NavigatorOne-way
Mediterranean 10 nights Nov 1 – Nov 11, 2026 from Civitavecchia (Rome), Italy to Barcelona, Spain
Civitavecchia (Rome), Italy · Willis Island · … · Barcelona, Spain11 ports
Civitavecchia (Rome), Italy · Willis Island · Valletta, Malta · La Goulette, Tunisia · Palermo, Sicily, Italy · Naples, Italy · Willis Island · Livorno (Florence/Pisa), Italy · Toulon, France · Palamos, Spain · Barcelona, Spain
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayZodiac Circumnavigation of Willis IslandSt John's Co-Cathedral & the Caravaggio masterpiecesPrivate Full-Day Carthage, Sidi Bou Said & Bardo M… +6 more
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from $6,399
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 7 nights Nov 2 – Nov 9, 2026 from Marseille, France
Marseille, France · Genoa, Italy · … · Marseille, France7 ports
Marseille, France · Genoa, Italy · Livorno (Florence/Pisa), Italy · Valencia, Spain · Palma de Mallorca, Spain · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockClimb the Leaning Tower of PisaOceanografic +2 more
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from $627
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Nov 2 – Nov 9, 2026 from Marseille, France
Marseille, France · Livorno (Florence/Pisa), Italy · … · Marseille, France7 ports
Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman Palace +2 more
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from $762
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 7 nights Nov 3 – Nov 10, 2026 from Genoa, Italy
Genoa, Italy · Livorno (Florence/Pisa), Italy · … · Genoa, Italy7 ports
Genoa, Italy · Livorno (Florence/Pisa), Italy · Valencia, Spain · Palma de Mallorca, Spain · Barcelona, Spain · Marseille, France · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockClimb the Leaning Tower of PisaOceanograficLa Seu Cathedral + Rooftop Terraces Climb +2 more
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from $651
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Nov 3 – Nov 10, 2026 from Livorno (Florence/Pisa), Italy
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · … · Livorno (Florence/Pisa), Italy7 ports
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy
★ Bucket-list Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpieces +2 more
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from $711
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Nov 4 – Nov 11, 2026 from Cagliari, Sardinia, Italy
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · … · Cagliari, Sardinia, Italy7 ports
Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy
★ Bucket-list Su Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada Familia +2 more
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from $1,482
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Viking Ocean · Viking JupiterOne-way
Mediterranean 7 nights Nov 4 – Nov 11, 2026 from Civitavecchia (Rome), Italy to Barcelona, Spain
Civitavecchia (Rome), Italy · Florence, Italy · … · Barcelona, Spain6 ports
Civitavecchia (Rome), Italy · Florence, Italy · Monte Carlo, Monaco · Marseille, France · Sete, France · Barcelona, Spain
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayUffizi GalleryCasino de Monte-CarloCalanques National Park Boat Cruise from the Old P… +2 more
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from $4,499
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Nov 5 – Nov 12, 2026 from Palermo, Sicily, Italy
Palermo, Sicily, Italy · Valletta, Malta · … · Palermo, Sicily, Italy7 ports
Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy
★ Bucket-list Cappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +2 more
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from $727
Book This Cruise@ Cruisebound
Oceania · Oceania MarinaOne-way
Mediterranean 10 nights Nov 5 – Nov 15, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Alicante, Spain · … · Civitavecchia (Rome), Italy11 ports
Barcelona, Spain · Alicante, Spain · Ibiza, Spain · Palma de Mallorca, Spain · Sete, France · Toulon, France · St. Tropez, France · Monte Carlo, Monaco · Portofino, Italy · Florence, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaCastillo de Santa BárbaraFormentera Day Trip & Ses Illetes, the 'Spanish Ca…La Seu Cathedral + Rooftop Terraces Climb +7 more
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from $4,025
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 8 nights Nov 6 – Nov 14, 2026 from Valencia, Spain
Valencia, Spain · Palma de Mallorca, Spain · … · Valencia, Spain8 ports
Valencia, Spain · Palma de Mallorca, Spain · Barcelona, Spain · Marseille, France · Genoa, Italy · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Valencia, Spain
★ Bucket-list OceanograficLa Seu Cathedral + Rooftop Terraces ClimbSagrada FamiliaCalanques National Park Boat Cruise from the Old P… +3 more
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from $562
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Nov 6 – Nov 13, 2026 from Valletta, Malta
Valletta, Malta · Barcelona, Spain · … · Valletta, Malta7 ports
Valletta, Malta · Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta
★ Bucket-list St John's Co-Cathedral & the Caravaggio masterpiecesSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of Pisa +2 more
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from $873
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 7 nights Nov 8 – Nov 15, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Genoa, Italy · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Valencia, Spain · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockClimb the Leaning Tower of Pisa +2 more
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from $571
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MSC Cruises · MSC SplendidaRound-trip
Mediterranean 7 nights Nov 8 – Nov 15, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di Barumini +2 more
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from $1,218
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 7 nights Nov 9 – Nov 16, 2026 from Marseille, France
Marseille, France · Genoa, Italy · … · Marseille, France7 ports
Marseille, France · Genoa, Italy · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Valencia, Spain · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One Day +2 more
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from $585
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MSC Cruises · MSC SplendidaRepositioning
Mediterranean 24 nights Nov 9 – Dec 3, 2026 from Marseille, France to Buenos Aires, Argentina
Marseille, France · Livorno (Florence/Pisa), Italy · … · Buenos Aires, Argentina14 ports
Marseille, France · Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Gibraltar, British Territory · Casablanca, Morocco · Las Palmas, Gran Canaria, Canary Islands · Maceio, Brazil · Bahia de Salvador, Brazil · Rio de Janeiro, Brazil · Montevideo, Uruguay · Buenos Aires, Argentina
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman Palace +10 more
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from $4,829
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 7 nights Nov 10 – Nov 17, 2026 from Genoa, Italy
Genoa, Italy · Livorno (Florence/Pisa), Italy · … · Genoa, Italy7 ports
Genoa, Italy · Livorno (Florence/Pisa), Italy · Civitavecchia (Rome), Italy · Valencia, Spain · Barcelona, Spain · Marseille, France · Genoa, Italy
★ Bucket-list Sail straight to Portofino from the cruise dockClimb the Leaning Tower of PisaVatican, Sistine Chapel & Colosseum in One DayOceanografic +2 more
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from $538
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MSC Cruises · MSC SplendidaRepositioning
Mediterranean 23 nights Nov 10 – Dec 3, 2026 from Livorno (Florence/Pisa), Italy to Buenos Aires, Argentina
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · … · Buenos Aires, Argentina13 ports
Livorno (Florence/Pisa), Italy · Cagliari, Sardinia, Italy · Palermo, Sicily, Italy · Valletta, Malta · Barcelona, Spain · Gibraltar, British Territory · Casablanca, Morocco · Las Palmas, Gran Canaria, Canary Islands · Maceio, Brazil · Bahia de Salvador, Brazil · Rio de Janeiro, Brazil · Montevideo, Uruguay · Buenos Aires, Argentina
★ Bucket-list Climb the Leaning Tower of PisaSu Nuraxi di BaruminiCappella Palatina & the Norman PalaceSt John's Co-Cathedral & the Caravaggio masterpieces +9 more
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from $3,531
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Viking Ocean · Viking NeptuneOne-way
Mediterranean 7 nights Nov 10 – Nov 17, 2026 from Civitavecchia (Rome), Italy to Barcelona, Spain
Civitavecchia (Rome), Italy · Florence, Italy · … · Barcelona, Spain6 ports
Civitavecchia (Rome), Italy · Florence, Italy · Monte Carlo, Monaco · Marseille, France · Sete, France · Barcelona, Spain
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayUffizi GalleryCasino de Monte-CarloCalanques National Park Boat Cruise from the Old P… +2 more
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from $5,299
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Viking Ocean · Viking SkyOne-way
Mediterranean 7 nights Nov 11 – Nov 18, 2026 from Civitavecchia (Rome), Italy to Barcelona, Spain
Civitavecchia (Rome), Italy · Florence, Italy · … · Barcelona, Spain6 ports
Civitavecchia (Rome), Italy · Florence, Italy · Monte Carlo, Monaco · Marseille, France · Sete, France · Barcelona, Spain
★ Bucket-list Vatican, Sistine Chapel & Colosseum in One DayUffizi GalleryCasino de Monte-CarloCalanques National Park Boat Cruise from the Old P… +2 more
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from $3,499
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Viking Ocean · Viking VestaOne-way
Mediterranean 7 nights Nov 11 – Nov 18, 2026 from Barcelona, Spain to Civitavecchia (Rome), Italy
Barcelona, Spain · Sete, France · … · Civitavecchia (Rome), Italy6 ports
Barcelona, Spain · Sete, France · Marseille, France · Monte Carlo, Monaco · Florence, Italy · Civitavecchia (Rome), Italy
★ Bucket-list Sagrada FamiliaPrivate Gastronomic VoyageCalanques National Park Boat Cruise from the Old P…Casino de Monte-Carlo +2 more
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from $3,799
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Oceania · Oceania SirenaOne-way
Mediterranean 39 nights Nov 12 – Dec 21, 2026 from Istanbul, Turkey to Lisbon, Portugal
Istanbul, Turkey · Bozcaada, Turkey · … · Lisbon, Portugal39 ports
Istanbul, Turkey · Bozcaada, Turkey · Mykonos, Greece · Piraeus (Athens), Greece · Gythion, Greece · Katakolon (Olympia), Greece · Igoumenitsa, Greece · Kotor, Montenegro · Dubrovnik, Croatia · Zadar, Croatia · Venice, Italy · Koper, Slovenia · Rijeka, Croatia · Split, Croatia · Bari, Italy · Corfu, Greece · Crotone · Valletta, Malta · Messina, Sicily, Italy · Naples, Italy · Civitavecchia (Rome), Italy · Bastia, France · Florence, Italy · La Spezia (Cinque Terre), Italy · Toulon, France · Palamos, Spain · Palma de Mallorca, Spain · Barcelona, Spain · Alicante, Spain · Almeria, Spain · Gibraltar, British Territory · Casablanca, Morocco · Agadir, Morocco · Arrecife, Lanzarote, Canary Islands · Las Palmas, Gran Canaria, Canary Islands · Santa Cruz de Tenerife, Canary Islands · Santa Cruz de La Palma, Spain · Funchal, Madeira, Portugal · Lisbon, Portugal
★ Bucket-list Hagia Sophia + the upper gallery mosaics with a li…DelosThe Acropolis & Parthenon, Guided Skip-the-LineDiros Caves +34 more
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from $17,899
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 6 nights Nov 14 – Nov 20, 2026 from Valencia, Spain
Valencia, Spain · Barcelona, Spain · … · Valencia, Spain6 ports
Valencia, Spain · Barcelona, Spain · Marseille, France · Genoa, Italy · Livorno (Florence/Pisa), Italy · Valencia, Spain
★ Bucket-list OceanograficSagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dock +1 more
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from $517
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 7 nights Nov 15 – Nov 22, 2026 from Barcelona, Spain
Barcelona, Spain · Marseille, France · … · Barcelona, Spain7 ports
Barcelona, Spain · Marseille, France · Genoa, Italy · Livorno (Florence/Pisa), Italy · Valencia, Spain · Palma de Mallorca, Spain · Barcelona, Spain
★ Bucket-list Sagrada FamiliaCalanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockClimb the Leaning Tower of Pisa +2 more
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from $591
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MSC Cruises · MSC SinfoniaRound-trip
Mediterranean 7 nights Nov 16 – Nov 23, 2026 from Marseille, France
Marseille, France · Genoa, Italy · … · Marseille, France7 ports
Marseille, France · Genoa, Italy · Livorno (Florence/Pisa), Italy · Valencia, Spain · Palma de Mallorca, Spain · Barcelona, Spain · Marseille, France
★ Bucket-list Calanques National Park Boat Cruise from the Old P…Sail straight to Portofino from the cruise dockClimb the Leaning Tower of PisaOceanografic +2 more
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from $563
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